Results 251 to 260 of about 248,807 (309)

Liposomal CRISPR/Cas9-Mediated Local Genome Editing for Joint Disease in Mucopolysaccharidosis Type I. [PDF]

Pharmaceutics
Santos HS, Poletto E, Vera LNP, Farinon M, Kubaski F, Carneiro PB, Carniel WDS, Giugliani R, Matte U, Teixeira HF, Schuh RS, Baldo G.   +11 more
europepmc   +1 more source

Decoding Undesirable Inflammatory Responses of Nucleic Acid‐Delivering Lipid Nanoparticles

Advanced Science, EarlyView.
Lipid nanoparticles (LNPs) enable efficient nucleic acid delivery, but their immunogenicity is a double‐edged sword. This review explores LNP‐driven innate and adaptive immunity, covering lipid components, endosomal escape, and nucleic acid sensing.
Ruimin Hu, Yin Dou, Chenwen Li, Yuying Mu, Huiying Ouyang, Wenhao Shen, Jianxiang Zhang   +6 more
wiley   +1 more source

Quantitative Proteomics and CRISPR/Cas9 Editing Reveal UPR-Mediated Control of Immunoglobulin Homeostasis in Hybridomas. [PDF]

Adv Sci (Weinh)
Zou R, Lu X, Liu Y, Yang P, Sun S, Liu Y, Mo Y, Zhu G, Lee JS, Guo Y.   +9 more
europepmc   +1 more source

Discovering CRISPR/Cas9

, 2016
Prieto Pascual, Cristina, Universitat Autònoma de Barcelona. Facultat de Biociències   +1 more
openaire   +1 more source

Influence of gRNA efficiency and inversion size on the frequency of CRISPR/Cas9-induced chromosomal inversions in tomato protoplasts. [PDF]

BMC Plant Biol
Grubben J, Bijsterbosch G, Visser RGF, Schouten HJ.   +3 more
europepmc   +1 more source

CRISPR-Cas9 Screening Identifies Resistance Mechanisms to KRAS Inhibition in Pancreatic Cancer. [PDF]

Cancer Res
Long SA, Todd H, Goodhart G, Chang WH, Amparo AM, Bridgens R, Dilly J, Park SJ, Beal RM, Shehadeh SM, Satyadi MA, Trivedi VK, Ackermann SE, Mukherjee R, Goodwin CM, Edwards AC, Stalnecker CA, Greis KD, Aguirre AJ, Hobbs GA, Bryant KL, Ahmad SA, Cox AD, Der CJ, Waters AM.   +24 more
europepmc   +1 more source

Anatomically Guided Non-Viral CRISPR/Cas9 Delivery in the Eye: Overcoming Barriers for Precision Gene Therapy. [PDF]

Pharmaceutics
Hua Z, Shen Y, Zhou X.
europepmc   +1 more source