Results 221 to 230 of about 18,275,652 (330)

Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics

Sheng Li, Han Li, Bojie Chen, Ling Jiang, Keyu Long, Jiaqi Lang, Xingxiang Pu, Erhu Xiong   +7 more
openalex   +1 more source

Oxidative stress elicited by phage infection induces Staphylococcal type III-A CRISPR-Cas system. [PDF]

Nucleic Acids Res
Li Y, Zhao C, Cao Y, Chen X, Tang Y, Zhou X, Ingmer H, Jiao X, Li Q.   +8 more
europepmc   +1 more source

The Mitogen‐Activated Protein Kinase GhNTF3 Modulates the Arbuscular Mycorrhizal Symbiosis‐Immunity Trade‐Off in Cotton by Regulating Salicylic Acid Biosynthesis

Advanced Science, EarlyView.
AM symbiosis induces GhWAK13 to promote fungal colonization. GhNTF3 negatively regulates symbiosis by promoting SA biosynthesis. GhWAK13 sequesters GhNTF3 at the membrane, limiting its nuclear translocation and relieving SA‐mediated suppression. Under Verticillium stress, GhNTF3 enters the nucleus and interacts with GhJAZ6 to activate SA signaling ...
Shuangjie Jia, Jingshang Wen, Jihang Li, Meina Feng, Yiming He, Ruojun Liu, Qian Liu, Junli Zhang, Kai Cheng, Xiangyu Zhang, Xiao Zhang   +10 more
wiley   +1 more source

CRISPR-Cas systems as next-generation antimicrobials: a systemic review of mechanisms, delivery strategies, and translational challenges [PDF]

Maha S.I. Wizrah
openalex   +1 more source

Functional characterization of a type I-F1 CRISPR-cas system from the clinical isolate Shewanella xiamenensis Sh95 reveals constitutive activity and plasmid-curing capability. [PDF]

Sci Rep
Molina MC, Quiroga C.
europepmc   +1 more source

An Effector TaCRVP From Tuta Absoluta Oral Secretion Impairs H2O2‐Mediated Plant Defense by Targeting Tomato SlCAT2

Advanced Science, EarlyView.
The Tuta absoluta salivary effector TaCRVP subverts tomato immunity by hijacking host catalase SlCAT2. Through a sophisticated dual mechanism, TaCRVP simultaneously promotes SlCAT2 tetramerization for activation and blocks its SlAdBiL‐mediated degradation for stabilization.
Jianquan Yan, Youdan Zhang, Zhujun Wang, Huatao Tang, Huiping Liu, Zi Chen, Shuai Liu, Jiayi Shi, Lu Peng, Youming Hou   +9 more
wiley   +1 more source

Mre11-Rad50 enhances spacer acquisition in a haloarchaeal Type I-B CRISPR-Cas system [PDF]

Alice K Cassell, Héloïse Carion, Luciano A. Marraffini   +2 more
openalex   +1 more source

Unveiling the endogenous CRISPR-Cas system in Pseudomonas aeruginosa PAO1. [PDF]

PLoS One
Delgado-Nungaray JA, Figueroa-Yáñez LJ, Reynaga-Delgado E, Corona-España AM, Gonzalez-Reynoso O.   +4 more
europepmc   +1 more source

Corynoxine Inhibits Tumor Growth via Targeting NQO1 and Modulating the PTPA–NQO1/PP2A Switch to Activate PP2A

Advanced Science, EarlyView.
Corynoxine exerts potent broad‐spectrum anticancer activity by directly targeting NQO1. This interaction dissociates the oncogenic NQO1‐PTPA complex, releasing PTPA to robustly activate the tumor suppressor PP2A. Consequently, downstream Raf/MEK/ERK and PI3K/AKT signaling pathways are suppressed, downregulating c‐Myc and driving tumor regression ...
Guoqing Hou, Li Lin, Mengjie Xia, Ruohan Liang, Yueyue Zhang, Linna Du, Xuan Cao   +6 more
wiley   +1 more source

Expanding the Microbial Genomic Landscape and Biotechnological Applications of CRISPR-Cas Systems [PDF]

Swati Singh, Harshita Tiwari, Mamta Singh, Vibhav Gautam, Anju Gautam, Hemant K. Gautam   +5 more
openalex   +1 more source