Results 51 to 60 of about 216,867 (346)
Hot and crispy : CRISPR-Cas systems in the hyperthermophile Sulfolobus solfataricus [PDF]
, 2013 The CRISPR (clustered regularly interspaced short palindromic repeats) and Cas (CRISPR-associated) genes are widely spread in bacteria and archaea, representing an intracellular defence system against invading viruses and plasmids.
White, Malcolm F., Zhang, Jing
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Drug Inducible CRISPR/Cas Systems
Computational and Structural Biotechnology Journal, 2019 Clustered, regularly interspaced, short palindromic repeats (CRISPR)/CRISPR-associated protein (Cas) systems have been employed as a powerful versatile technology for programmable gene editing, transcriptional modulation, epigenetic modulation, and genome labeling, etc.
Jingfang Zhang +3 more
openaire +3 more sources
Determination of Acr-mediated immunosuppression in Pseudomonas aeruginosa
MethodsX, 2023 Bacteria have a broad array of defence mechanisms to fight bacteria-specific viruses (bacteriophages, phages) and other invading mobile genetic elements. Among those mechanisms, the ‘CRISPR-Cas’ (Clustered Regularly Interspaced Short Palindromic Repeats –
Benoit J. Pons +2 more
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Role of CRISPR-Cas system on antibiotic resistance patterns of Enterococcus faecalis
Annals of Clinical Microbiology and Antimicrobials, 2021 Clustered regularly interspaced short palindromic repeat (CRISPR)-Cas systems are one of the factors which can contribute to limiting the development and evolution of antibiotic resistance in bacteria.
P. Gholizadeh +9 more
semanticscholar +1 more source
Efficient genome editing in zebrafish using a CRISPR-Cas system [PDF]
, 2013 In bacteria, foreign nucleic acids are silenced by clustered, regularly interspaced, short palindromic repeats (CRISPR)--CRISPR-associated (Cas) systems.
Fu, Yanfang +8 more
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How CRISPR-Cas System Could Be Used to Combat Antimicrobial Resistance
Infection and Drug Resistance, 2020 Rapid emergence of antibiotic-resistant bacteria has made it harder for us to combat infectious diseases and to develop new antibiotics. The clustered regularly interspaced short palindromic repeats – CRISPR-associated (CRISPR-Cas) system, as a bacterial
P. Gholizadeh +10 more
semanticscholar +1 more source
Therapeutic Applications of the CRISPR-Cas System
Bioengineering, 2022 The clustered regularly interspaced palindromic repeat (CRISPR)-Cas system has revolutionized genetic engineering due to its simplicity, stability, and precision since its discovery. This technology is utilized in a variety of fields, from basic research in medicine and biology to medical diagnosis and treatment, and its potential is unbounded as new ...
Kyungmin Kang +3 more
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Frontiers in Microbiology, 2018 Prokaryotic CRISPR-Cas systems limit the acquisition of genetic elements and provide immunity against invasive bacteriophage. The characteristics of CRISPR-Cas systems in clinical Klebsiella pneumoniae isolates are still unknown. Here, 97 K.
Hsin-Yu Li +8 more
doaj +1 more source
Development and Application of CRISPR/Cas in Microbial Biotechnology
Frontiers in Bioengineering and Biotechnology, 2020 The clustered regularly interspaced short palindromic repeats (CRISPR)-associated (Cas) system has been rapidly developed as versatile genomic engineering tools with high efficiency, accuracy and flexibility, and has revolutionized traditional methods ...
Wentao Ding +3 more
doaj +1 more source
CRISPR-spacer integration reporter plasmids reveal distinct genuine acquisition specificities among CRISPR-Cas I-E variants of Escherichia coli [PDF]
, 2013 Prokaryotes immunize themselves against transmissible genetic elements by the integration (acquisition) in clustered regularly interspaced short palindromic repeats (CRISPR) loci of spacers homologous to invader nucleic acids, defined as protospacers ...
Almendros, Cristóbal +4 more
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