Strategies for High-Efficiency Mutation Using the CRISPR/Cas System
Frontiers in Cell and Developmental Biology, 2022 Clustered regularly interspaced short palindromic repeats (CRISPR)-associated systems have revolutionized traditional gene-editing tools and are a significant tool for ameliorating gene defects.
Shuying Feng +10 more
semanticscholar +1 more source
Aplicación de la nanobiotecnología con el sistema CRISPR-cas [PDF]
, 2017 Introduction: Nanobiotechnology and synthetic biology are sciences that impact today with the launching of innovative and beneficial applications for the human being. These sciences have been amalgamated to manufacture new components for the construction
Angarita-Merchán, Maritza +2 more
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Genome editing using the endogenous type I CRISPR-Cas system in Lactobacillus crispatus
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance Lactobacillus crispatus primarily inhabits 2 ecological niches: the human vagina and the poultry intestine. The predominance of this commensal species is indicative of a healthy status, and this species has become intriguing as an emerging ...
C. Hidalgo-Cantabrana +4 more
semanticscholar +1 more source
Production and analysis of synthetic Cascade variants [PDF]
, 2020 CRISPR (clustered regularly interspaced short palindromic repeats)-Cas (CRISPR assoziiert) ist ein adaptives Immunsystem in Archaeen und Bakterien, das fremdes genetisches Material mit Hilfe von Ribonukleoprotein-Komplexen erkennt und zerstört.
Gleditzsch, Daniel
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CRISPR-associated sequence diversity within Xanthomonas albilineans, the causal agent of leaf scald disease of sugarcane. [PDF]
, 2012 Xanthomonas albilineans is a xylem-invading pathogen that causes leaf scald, a lethal disease of sugarcane. Unlike other xanthomonads, X. albilineans exhibits a large intra-species variability which was previously observed with different genetic markers (
Bolot, Stéphanie +7 more
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CRISPR/Cas: A powerful tool for gene function study and crop improvement
Journal of Advanced Research, 2021 Background: It is a long-standing goal of scientists and breeders to precisely control a gene for studying its function as well as improving crop yield, quality, and tolerance to various environmental stresses.
Dangquan Zhang +3 more
doaj +1 more source
CRISPR/Cas System: Recent Advances and Future Prospects for Genome Editing.
Trends in Plant Science, 2019 Genome editing (GE) has revolutionized biological research through the new ability to precisely edit the genomes of living organisms. In recent years, various GE tools have been explored for editing simple and complex genomes.
Hakim Manghwar +3 more
semanticscholar +1 more source
Diversity of CRISPR-Cas type II-A systems in Streptococcus anginosus
Frontiers in Microbiology, 2023 Streptococcus anginosus is a commensal Streptococcal species that is often associated with invasive bacterial infections. However, little is known about its molecular genetic background. Many Streptococcal species, including S.
Richard Bauer +5 more
doaj +1 more source
How the other half lives: CRISPR-Cas's influence on bacteriophages
, 2017 CRISPR-Cas is a genetic adaptive immune system unique to prokaryotic cells used to combat phage and plasmid threats. The host cell adapts by incorporating DNA sequences from invading phages or plasmids into its CRISPR locus as spacers.
AE Briner +35 more
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Hutchinson Gilford Progeria Syndrome: A Therapeutic Approach via Adenoviral Delivery of CRISPR/cas Genome Editing System [PDF]
, 2014 Hutchinson-Gilford Progeria Syndrome (HGPS) is a rare human genetic disease caused by mutations in the LMNA gene. LMNA codes for structural components of the nuclear lamina. Alterations of nuclear lamina lead to a very variable class of diseases known as
ARANCIO, Walter +3 more
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