Results 1 to 10 of about 59,081 (323)

Applications of CRISPR–Cas systems in neuroscience [PDF]

open access: greenNature Reviews Neuroscience, 2015
Genome-editing tools, and in particular those based on CRISPR-Cas (clustered regularly interspaced short palindromic repeat (CRISPR)-CRISPR-associated protein) systems, are accelerating the pace of biological research and enabling targeted genetic ...
Matthias Heidenreich, Feng Zhang
core   +9 more sources

Mechanisms regulating the CRISPR-Cas systems [PDF]

open access: yesFrontiers in Microbiology, 2023
The CRISPR-Cas (Clustered Regularly Interspaced Short Palindromic Repeats- CRISPR associated proteins) is a prokaryotic system that enables sequence specific recognition and cleavage of nucleic acids.
Marta Zakrzewska   +3 more
doaj   +4 more sources

Viral Diversity Threshold for Adaptive Immunity in Prokaryotes [PDF]

open access: yesmBio, 2012
Bacteria and archaea face continual onslaughts of rapidly diversifying viruses and plasmids. Many prokaryotes maintain adaptive immune systems known as clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated genes (Cas ...
Ariel D. Weinberger   +4 more
doaj   +3 more sources

Occurrence and Diversity of CRISPR-Cas Systems in the Genus Bifidobacterium. [PDF]

open access: yesPLoS ONE, 2015
CRISPR-Cas systems constitute adaptive immune systems for antiviral defense in bacteria. We investigated the occurrence and diversity of CRISPR-Cas systems in 48 Bifidobacterium genomes to gain insights into the diversity and co-evolution of CRISPR-Cas ...
Alexandra E Briner   +9 more
doaj   +3 more sources

CRISPR-Cas systems feature and targeting phages diversity in Lacticaseibacillus rhamnosus strains [PDF]

open access: yesFrontiers in Microbiology, 2023
One of the most important adaptive immune systems in bacteria against phages is clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (CAS) genes.
Bahman Panahi   +2 more
doaj   +2 more sources

Distribution of Genetic Determinants Associated with CRISPR-Cas Systems and Resistance to Antibiotics in the Genomes of Archaea and Bacteria [PDF]

open access: yesMicroorganisms
The CRISPR-Cas system represents an adaptive immune mechanism found across diverse Archaea and Bacteria, allowing them to defend against invading genetic elements such as viruses and plasmids. Despite its broad distribution, the prevalence and complexity
Laura Antequera-Zambrano   +4 more
doaj   +2 more sources

Comprehensive Analysis of CRISPR-Cas Systems and Their Influence on Antibiotic Resistance in Strains [PDF]

open access: yesBioinformatics and Biology Insights
Salmonella enterica is a gram-negative bacterium that demonstrates a remarkable ability to acquire antibiotic resistance genes (ARGs). The role of the CRISPR-Cas system in influencing antibiotic resistance in S.
Tina Fallah, Morvarid Shafiei
doaj   +2 more sources

Characterization of Ligilactobacillus salivarius CRISPR-Cas systems [PDF]

open access: yesmSphere
Ligilactobacillus is a diverse genus among lactobacilli with phenotypes that reflect adaptation to various hosts. CRISPR-Cas systems are highly prevalent within lactobacilli, and Ligilactobacillus salivarius, the most abundant species of ...
Avery Roberts   +4 more
doaj   +2 more sources

Physical model of the immune response of bacteria against bacteriophage through the adaptive CRISPR-Cas immune system [PDF]

open access: green, 2013
Bacteria and archaea have evolved an adaptive, heritable immune system that recognizes and protects against viruses or plasmids. This system, known as the CRISPR-Cas system, allows the host to recognize and incorporate short foreign DNA or RNA sequences,
Pu Han   +3 more
openalex   +4 more sources

Cold Cas: reevaluating the occurrence of CRISPR/Cas systems in Mycobacteriaceae [PDF]

open access: yesFrontiers in Microbiology, 2023
Bacterial CRISPR/Cas systems target foreign genetic elements such as phages and regulate gene expression by some pathogens, even in the host. The system is a marker for evolutionary history and has been used for inferences in Mycobacterium tuberculosis ...
Evan Brenner, Srinand Sreevatsan
doaj   +2 more sources

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