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Functional Coupling and Evolutionary Relationships Between Toxin–Antitoxin Systems and CRISPR-Cas Systems [PDF]

open access: yesToxins
Bacteria encode a broad range of survival and defence systems, including CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)-Cas systems, restriction-modification systems, and toxin–antitoxin (TA) systems, which are involved in bacterial ...
Yibo Meng, Jiyun Chen, Liang Liu
doaj   +2 more sources

CRISPR-Cas systems in enterococci. [PDF]

open access: yesBraz J Microbiol
Enterococci are members of the microbiota of humans and other animals. They can also be found in the environment, associated with food, healthcare infections, and hospital settings. Due to their wide distribution, they are inserted in the One Health context.
Cabral AS   +8 more
europepmc   +3 more sources

Distribution of Genetic Determinants Associated with CRISPR-Cas Systems and Resistance to Antibiotics in the Genomes of Archaea and Bacteria [PDF]

open access: yesMicroorganisms
The CRISPR-Cas system represents an adaptive immune mechanism found across diverse Archaea and Bacteria, allowing them to defend against invading genetic elements such as viruses and plasmids. Despite its broad distribution, the prevalence and complexity
Laura Antequera-Zambrano   +4 more
doaj   +2 more sources

Mechanisms regulating the CRISPR-Cas systems

open access: yesFrontiers in Microbiology, 2023
The CRISPR-Cas (Clustered Regularly Interspaced Short Palindromic Repeats- CRISPR associated proteins) is a prokaryotic system that enables sequence specific recognition and cleavage of nucleic acids.
Marta Zakrzewska   +3 more
doaj   +3 more sources

Characterization of Ligilactobacillus salivarius CRISPR-Cas systems [PDF]

open access: yesmSphere
Ligilactobacillus is a diverse genus among lactobacilli with phenotypes that reflect adaptation to various hosts. CRISPR-Cas systems are highly prevalent within lactobacilli, and Ligilactobacillus salivarius, the most abundant species of ...
Avery Roberts   +4 more
doaj   +2 more sources

Comprehensive Analysis of CRISPR-Cas Systems and Their Influence on Antibiotic Resistance in Strains [PDF]

open access: yesBioinformatics and Biology Insights
Salmonella enterica is a gram-negative bacterium that demonstrates a remarkable ability to acquire antibiotic resistance genes (ARGs). The role of the CRISPR-Cas system in influencing antibiotic resistance in S.
Tina Fallah, Morvarid Shafiei
doaj   +2 more sources

Genome mining approach reveals the CRISPR-Cas systems features and characteristics in Lactobacillus delbrueckii strains [PDF]

open access: yesHeliyon
This study employed a comprehensive genome-mining approach to characterize CRISPR-Cas systems in Lactobacillus delbrueckii strains. The analysis involved retrieving 105 genome sequences to explore the variety, occurrence, and evolution of CRISPR-Cas ...
Bahman Panahi   +3 more
doaj   +2 more sources

CASPredict: a web service for identifying Cas proteins [PDF]

open access: yesPeerJ, 2021
Clustered regularly interspaced short palindromic repeats (CRISPR) and their associated (Cas) proteins constitute the CRISPR-Cas systems, which play a key role in prokaryote adaptive immune system against invasive foreign elements.
Shanshan Yang, Jian Huang, Bifang He
doaj   +2 more sources

Comparison of CRISPR–Cas Immune Systems in Healthcare-Related Pathogens

open access: yesFrontiers in Microbiology, 2021
The ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species) and Clostridium difficile have been identified as the leading global cause of multidrug ...
Kate Mortensen, Tony J. Lam, Yuzhen Ye
doaj   +1 more source

Phylogenetic Distribution of CRISPR-Cas Systems in Staphylococcus lugdunensis

open access: yesMicrobiology Spectrum, 2021
Clustered regularly interspaced short palindromic repeats (CRISPRs) and CRISPR-associated (Cas) genes (CRISPR-Cas) are present in many bacterial genomes with functions beyond adaptive immunity.
Cheng-Yen Kao   +4 more
doaj   +1 more source

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