Results 11 to 20 of about 39,519 (255)

Mechanisms regulating the CRISPR-Cas systems

Frontiers in Microbiology, 2023
The CRISPR-Cas (Clustered Regularly Interspaced Short Palindromic Repeats- CRISPR associated proteins) is a prokaryotic system that enables sequence specific recognition and cleavage of nucleic acids.
Marta Zakrzewska, Marta Zakrzewska, Michal Burmistrz, Michal Burmistrz   +3 more
doaj   +3 more sources

CRISPR-Cas systems in enterococci. [PDF]

Braz J Microbiol
Enterococci are members of the microbiota of humans and other animals. They can also be found in the environment, associated with food, healthcare infections, and hospital settings. Due to their wide distribution, they are inserted in the One Health context.
Cabral AS, Lacerda FF, Leite VLM, de Miranda FM, da Silva AB, Dos Santos BA, Lima JLDC, Teixeira LM, Neves FPG.   +8 more
europepmc   +3 more sources

CRISPR-Cas Systems in Prokaryotes [PDF]

Polish Journal of Microbiology, 2015
Prokaryotic organisms possess numerous strategies that enable survival in hostile conditions. Among others, these conditions include the invasion of foreign nucleic acids such as bacteriophages and plasmids. The clustered regularly interspaced palindromic repeats-CRISPR-associated proteins (CRISPR-Cas) system provides the majority of bacteria and ...
Burmistrz, Michał, Pyrć, Krzysztof
openaire   +3 more sources

Adaptation in CRISPR-Cas Systems [PDF]

Molecular Cell, 2016
Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) proteins constitute an adaptive immune system in prokaryotes. The system preserves memories of prior infections by integrating short segments of foreign DNA, termed spacers, into the CRISPR array in a process termed adaptation.
Samuel H. Sternberg, Hagen Richter, Emmanuelle Charpentier, Udi Qimron   +3 more
openaire   +4 more sources

CRISPR-Cas Systems in Streptococci [PDF]

Current Issues in Molecular Biology, 2019
Streptococci are one of the most important and common constituents of the host's microbiota and can colonize and live in the upper respiratory and urogenital tract of humans and animals. The CRISPR-Cas systems (i.e., clustered regularly interspaced short palindromic repeat, with CRISPR-associated proteins) found in bacteria and archaea provide sequence-
Tao, Gong, Miao, Lu, Xuedong, Zhou, Anqi, Zhang, Boyu, Tang, Jiamin, Chen, Meiling, Jing, Yuqing, Li   +7 more
openaire   +2 more sources

The CRISPR-Cas system in Enterobacteriaceae [PDF]

Pathogens and Disease, 2018
In nature, microorganisms are constantly exposed to multiple viral infections and thus have developed many strategies to survive phage attack and invasion by foreign DNA. One of such strategies is the clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated proteins (Cas) bacterial immunological system.
Liliana, Medina-Aparicio, Sonia, Dávila, Javier E, Rebollar-Flores, Edmundo, Calva, Ismael, Hernández-Lucas   +4 more
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CRISPR-Cas systems in multicellular cyanobacteria [PDF]

RNA Biology, 2018
Novel CRISPR-Cas systems possess substantial potential for genome editing and manipulation of gene expression. The types and numbers of CRISPR-Cas systems vary substantially between different organisms. Some filamentous cyanobacteria harbor > 40 different putative CRISPR repeat-spacer cassettes, while the number of cas gene instances is much lower ...
Shengwei Hou, Manuel Brenes-Álvarez, Viktoria Reimann, Omer S. Alkhnbashi, Rolf Backofen, Alicia M. Muro-Pastor, Wolfgang R. Hess   +6 more
openaire   +4 more sources

Occurrence and Diversity of CRISPR-Cas Systems in the Genus Bifidobacterium. [PDF]

PLoS ONE, 2015
CRISPR-Cas systems constitute adaptive immune systems for antiviral defense in bacteria. We investigated the occurrence and diversity of CRISPR-Cas systems in 48 Bifidobacterium genomes to gain insights into the diversity and co-evolution of CRISPR-Cas ...
Alexandra E Briner, Gabriele Andrea Lugli, Christian Milani, Sabrina Duranti, Francesca Turroni, Miguel Gueimonde, Abelardo Margolles, Douwe van Sinderen, Marco Ventura, Rodolphe Barrangou   +9 more
doaj   +1 more source

Nonviral Delivery of CRISPR/Cas Systems in mRNA Format

Advanced NanoBiomed Research, 2022
The clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR‐associated (Cas) genome editing system provides a powerful toolbox for genetic engineering.
Zhen Liu, Zhenghua Li, Bin Li
doaj   +1 more source

An Endogenous Staphylococcus aureus CRISPR-Cas System Limits Phage Proliferation and Is Efficiently Excised from the Genome as Part of the SCCmec Cassette

Microbiology Spectrum, 2023
CRISPR-Cas is an adaptive immune system that allows bacteria to inactivate mobile genetic elements. Approximately 50% of bacteria harbor CRISPR-Cas; however, in the human pathogen Staphylococcus aureus, CRISPR-Cas loci are less common and often studied ...
Kasper Mikkelsen, Janine Zara Bowring, Yong Kai Ng, Frida Svanberg Frisinger, Julie Kjærsgaard Maglegaard, Qiuchun Li, Raphael N. Sieber, Andreas Petersen, Paal Skytt Andersen, Jakob T. Rostøl, Nina Molin Høyland-Kroghsbo, Hanne Ingmer   +11 more
doaj   +1 more source