Results 11 to 20 of about 64,886 (293)

Genome mining approach reveals the CRISPR-Cas systems features and characteristics in Lactobacillus delbrueckii strains [PDF]

open access: yesHeliyon
This study employed a comprehensive genome-mining approach to characterize CRISPR-Cas systems in Lactobacillus delbrueckii strains. The analysis involved retrieving 105 genome sequences to explore the variety, occurrence, and evolution of CRISPR-Cas ...
Bahman Panahi   +3 more
doaj   +2 more sources

CASPredict: a web service for identifying Cas proteins [PDF]

open access: yesPeerJ, 2021
Clustered regularly interspaced short palindromic repeats (CRISPR) and their associated (Cas) proteins constitute the CRISPR-Cas systems, which play a key role in prokaryote adaptive immune system against invasive foreign elements.
Shanshan Yang, Jian Huang, Bifang He
doaj   +2 more sources

Comparison of CRISPR–Cas Immune Systems in Healthcare-Related Pathogens

open access: yesFrontiers in Microbiology, 2021
The ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species) and Clostridium difficile have been identified as the leading global cause of multidrug ...
Kate Mortensen, Tony J. Lam, Yuzhen Ye
doaj   +1 more source

Phylogenetic Distribution of CRISPR-Cas Systems in Staphylococcus lugdunensis

open access: yesMicrobiology Spectrum, 2021
Clustered regularly interspaced short palindromic repeats (CRISPRs) and CRISPR-associated (Cas) genes (CRISPR-Cas) are present in many bacterial genomes with functions beyond adaptive immunity.
Cheng-Yen Kao   +4 more
doaj   +1 more source

CRISPR-Cas systems feature and targeting phages diversity in Lacticaseibacillus rhamnosus strains

open access: yesFrontiers in Microbiology, 2023
One of the most important adaptive immune systems in bacteria against phages is clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (CAS) genes.
Bahman Panahi   +2 more
doaj   +1 more source

Das CRISPR/Cas‐System [PDF]

open access: yesBiologie in unserer Zeit, 2018
Pflanzen können von einer Vielzahl an Pathogenen befallen werden, die schwerwiegende Krankheiten auslösen und besonders bei Nutzpflanzen zu starken Ernteverlusten beitragen. CRISPR/Cas‐Systeme verändern die Angriffsstellen dieser Pathogene hochpräzise, sodass ein Befall nicht mehr stattfinden kann – eine Entwicklung, die als Revolution in der ...
Patrick Schindele   +2 more
openaire   +2 more sources

Adaptation in CRISPR-Cas Systems [PDF]

open access: yesMolecular Cell, 2016
Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) proteins constitute an adaptive immune system in prokaryotes. The system preserves memories of prior infections by integrating short segments of foreign DNA, termed spacers, into the CRISPR array in a process termed adaptation.
Samuel H. Sternberg   +3 more
openaire   +4 more sources

CRISPR-Cas Systems in Streptococci [PDF]

open access: yesCurrent Issues in Molecular Biology, 2019
Streptococci are one of the most important and common constituents of the host's microbiota and can colonize and live in the upper respiratory and urogenital tract of humans and animals. The CRISPR-Cas systems (i.e., clustered regularly interspaced short palindromic repeat, with CRISPR-associated proteins) found in bacteria and archaea provide sequence-
Tao, Gong   +7 more
openaire   +2 more sources

New CRISPR-Cas systems discovered [PDF]

open access: yesCell Research, 2017
In bacteria and archaea, CRISPR-Cas adaptive immune systems utilize RNA-guided endonucleases to defend against invasion by foreign nucleic acids of bacteriophage, virus and plasmid origin. In a recent paper published in Nature, Burstein et al. identified the first Cas9 protein in uncultivated archaea and two novel CRISPR-CasX and CRISPR-CasY systems in
Hui, Yang, Dinshaw J, Patel
openaire   +2 more sources

Nonviral Delivery of CRISPR/Cas Systems in mRNA Format

open access: yesAdvanced NanoBiomed Research, 2022
The clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR‐associated (Cas) genome editing system provides a powerful toolbox for genetic engineering.
Zhen Liu, Zhenghua Li, Bin Li
doaj   +1 more source

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