Results 131 to 140 of about 2,853,090 (311)

Alienation - a long-overlooked concept of relevance to social work?

open access: yesSocial Work and Society, 2019
Alienation is seemingly a relevant concept in social work in so far as this concerns marginalized and vulnerable groups of people. Nevertheless, the interest in alienation theory has declined within social science as a whole, partly due to postmodern ...
Henrik Skovlund
doaj   +2 more sources

Multiplicity of solutions for gradient systems

open access: yesElectronic Journal of Differential Equations, 2010
We establish the existence of nontrivial solutions for an elliptic system which is resonant both at the origin and at infinity. The resonance is given by an eigenvalue problem with indefinite weight, and the nonlinear term is permitted to be unbounded.
Edcarlos D. Da Silva
doaj  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Are Groups more Rational than Individuals? A Review of Interactive Decision Making in Groups [PDF]

open access: yes
Many decisions are interactive; the outcome of one party depends not only on its decisions or on acts of nature but also on the decisions of others. In the present article, we review the literature on decision making made by groups of the past 25 years ...
Tamar Kugler   +2 more
core  

Critical Pedagogy in English Teacher Professional Development: The Experience of a Study Group

open access: yesIkala: Revista de Lenguaje y Cultura, 2015
In this article, we present the findings of a case study, which aimed to explore the experience of a study group, which was comprised of English teachers from different contexts.
Paula Andrea Echeverri-Sucerquia   +2 more
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Critical care dependency tool: Monitoring the changes

open access: yes, 2001
The critical care patient dependency system (CCPD) is a factorial patient acuity system developed in 1993 by Ferguson and Harris-Ingall1 for use in adult critical care areas. It was developed specifically to help determine Australian nursing cost weights
Donoghue, J   +7 more
core   +1 more source

Between experience and structure: Social suffering, collective identities and justice in Iris Marion Young

open access: yesDigithum, 2019
This paper analyzes the role of phenomenology in Iris Marion Young´s model of critical theory through a discussion of the different strategies she mobilizes in articulating the notions of identity and social collectivities in Justice and the Politics of
Gustavo Lima e Silva   +1 more
doaj   +2 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

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