Results 1 to 10 of about 6,265,278 (433)
Nature Medicine, 2022 Research and practice in critical care medicine have long been defined by syndromes, which, despite being clinically recognizable entities, are, in fact, loose amalgams of heterogeneous states that may respond differently to therapy. Mounting translational evidence-supported by research on respiratory failure due to severe acute respiratory syndrome ...
D. Maslove +38 more
semanticscholar +9 more sources
Unique lymphocyte transcriptomic profiles in septic patients with chronic critical illness [PDF]
Frontiers in ImmunologyIntroductionDespite continued improvement in post-sepsis survival, long term morbidity and mortality remain high. Chronic critical illness (CCI), defined as persistent inflammation and organ injury requiring prolonged intensive care, is a harbinger of ...
Evan L. Barrios +27 more
doaj +2 more sources
Antioxidants in Critical Illness [PDF]
Archives of Surgery, 2001 Oxidative stress has been implicated in the manifestations of critical illnesses, including ischemia and reperfusion injury and systemic inflammatory states. This review describes the evidence for increased oxidative stress in critically ill patients and explores the data regarding antioxidant therapy for these conditions.
Eileen M. Bulger, Ronald V. Maier
openalex +3 more sources
Transformations of self: a phenomenological investigation into the lived experience of survivors of critical illness [PDF]
, 2003 Based on the hermeneutical, phenomenological perspective, this study explored the lived experience of individuals with a past hospitalization in an intensive care unit, with focus on their dreams.
Papathanassoglou, Elizabeth +1 more
core +4 more sources
Procalcitonin in Critical Illness
Critical Care and Resuscitation, 2001 To detail the biology and diagnostic usefulness of serum procalcitonin in critical illness.A review of articles published in peer reviewed journals from 1990 to 2001 and identified through a MEDLINE search on procalcitonin.Procalcitonin (PCT) is a prohormone of calcitonin.
Enda O’Connor +4 more
openalex +3 more sources
Statins in the critically ill [PDF]
Annals of Intensive Care, 2012 The use or misuse of statins in critically ill patients recently attracted the attention of intensive care clinicians. Indeed, statins are probably the most common chronic treatment before critical illness and some recent experimental and clinical data demonstrated their beneficial effects during sepsis, acute lung injury (ALI)/acute respiratory ...
De Loecker, Isabelle +1 more
openaire +4 more sources
Critical Care Explorations, 2022 OBJECTIVE:. To conduct a systematic review to summarize cognitive instruments being used in long-term outcome studies of survivors of adult critical illness, as well as evaluate whether these measures are reported as using patient demographic norms ...
Rameela Raman, PhD +9 more
doaj +1 more source
A neutrophil activation signature predicts critical illness and mortality in COVID-19
Blood Advances, 2021 Pathologic immune hyperactivation is emerging as a key feature of critical illness in COVID-19, but the mechanisms involved remain poorly understood.
Matthew L. Meizlish +29 more
semanticscholar +1 more source
Critical Care, 2023 Objective To evaluate the safety, feasibility, and efficacy of combined adrenergic blockade with propranolol and clonidine in patients with severe traumatic brain injury (TBI).
Mina F. Nordness +16 more
doaj +1 more source
Towards definitions of critical illness and critical care using concept analysis
BMJ Open, 2022 Objective As ‘critical illness’ and ‘critical care’ lack consensus definitions, this study aimed to explore how the concepts’ are used, describe their defining attributes, and propose potential definitions. Design and methods We used the Walker and Avant
R. Kayambankadzanja, +7 more
semanticscholar +1 more source