Results 1 to 10 of about 5,763,057 (244)
Nature Medicine, 2022 Research and practice in critical care medicine have long been defined by syndromes, which, despite being clinically recognizable entities, are, in fact, loose amalgams of heterogeneous states that may respond differently to therapy. Mounting translational evidence-supported by research on respiratory failure due to severe acute respiratory syndrome ...
Maslove, David M +38 more
openaire +9 more sources
Chrononutrition in Critical Illness. [PDF]
Nutr RevAbstract Circadian rhythms in humans are biological rhythms that regulate various physiological processes within a 24-hour time frame. Critical illness can disrupt the circadian rhythm, as can environmental and clinical factors, including altered light exposure, organ replacement therapies, disrupted sleep–wake cycles, noise, continuous ...
Sagun E, Akyol A, Kaymak C.
europepmc +3 more sources
Procalcitonin in Critical Illness
Critical Care and Resuscitation, 2001 To detail the biology and diagnostic usefulness of serum procalcitonin in critical illness.A review of articles published in peer reviewed journals from 1990 to 2001 and identified through a MEDLINE search on procalcitonin.Procalcitonin (PCT) is a prohormone of calcitonin.
Enda O’Connor +4 more
openalex +3 more sources
Antioxidants in Critical Illness [PDF]
Archives of Surgery, 2001 Oxidative stress has been implicated in the manifestations of critical illnesses, including ischemia and reperfusion injury and systemic inflammatory states. This review describes the evidence for increased oxidative stress in critically ill patients and explores the data regarding antioxidant therapy for these conditions.
Eileen M. Bulger, Ronald V. Maier
openalex +3 more sources
Critical Care, 2023 Background Patients with critical illness can lose more than 15% of muscle mass in one week, and this can have long-term detrimental effects. However, there is currently no synthesis of the data of intensive care unit (ICU) muscle wasting studies, so the
Brigitta Fazzini +7 more
semanticscholar +1 more source
Pharmacokinetic Alterations Associated with Critical Illness
Clinical Pharmacokinetics, 2023 Haemodynamic, metabolic, and biochemical derangements in critically ill patients affect drug pharmacokinetics and pharmacodynamics making dose optimisation particularly challenging.
D. Morales Castro +3 more
semanticscholar +1 more source
Statins in the critically ill [PDF]
Annals of Intensive Care, 2012 The use or misuse of statins in critically ill patients recently attracted the attention of intensive care clinicians. Indeed, statins are probably the most common chronic treatment before critical illness and some recent experimental and clinical data demonstrated their beneficial effects during sepsis, acute lung injury (ALI)/acute respiratory ...
De Loecker, Isabelle +1 more
openaire +4 more sources
A neutrophil activation signature predicts critical illness and mortality in COVID-19
Blood Advances, 2021 Pathologic immune hyperactivation is emerging as a key feature of critical illness in COVID-19, but the mechanisms involved remain poorly understood.
Matthew L. Meizlish +29 more
semanticscholar +1 more source
Critical Care, 2023 Objective To evaluate the safety, feasibility, and efficacy of combined adrenergic blockade with propranolol and clonidine in patients with severe traumatic brain injury (TBI).
Mina F. Nordness +16 more
doaj +1 more source
British medical journal, 2020 Objective To describe outcomes of people admitted to hospital with coronavirus disease 2019 (covid-19) in the United States, and the clinical and laboratory characteristics associated with severity of illness. Design Prospective cohort study.
C. Petrilli +9 more
semanticscholar +1 more source