Results 1 to 10 of about 6,957,076 (388)
Nature Medicine, 2022 Research and practice in critical care medicine have long been defined by syndromes, which, despite being clinically recognizable entities, are, in fact, loose amalgams of heterogeneous states that may respond differently to therapy. Mounting translational evidence-supported by research on respiratory failure due to severe acute respiratory syndrome ...
D. Maslove +38 more
semanticscholar +11 more sources
Rehabilitation after critical illness [PDF]
BMJ, 2021 Essential for all intensive care patients, not just people recovering from covid ...
Catherine White +2 more
semanticscholar +4 more sources
Chrononutrition in Critical Illness. [PDF]
Nutr RevAbstract Circadian rhythms in humans are biological rhythms that regulate various physiological processes within a 24-hour time frame. Critical illness can disrupt the circadian rhythm, as can environmental and clinical factors, including altered light exposure, organ replacement therapies, disrupted sleep–wake cycles, noise, continuous ...
Sagun E, Akyol A, Kaymak C.
europepmc +3 more sources
Critical Care, 2023 Background Patients with critical illness can lose more than 15% of muscle mass in one week, and this can have long-term detrimental effects. However, there is currently no synthesis of the data of intensive care unit (ICU) muscle wasting studies, so the
Brigitta Fazzini +7 more
semanticscholar +1 more source
Pharmacokinetic Alterations Associated with Critical Illness
Clinical Pharmacokinetics, 2023 Haemodynamic, metabolic, and biochemical derangements in critically ill patients affect drug pharmacokinetics and pharmacodynamics making dose optimisation particularly challenging.
D. Morales Castro +3 more
semanticscholar +1 more source
Do critical illness survivors with multimorbidity need a different model of care?
Critical Care, 2023 There is currently a lack of evidence on the optimal strategy to support patient recovery after critical illness. Previous research has largely focussed on rehabilitation interventions which aimed to address physical, psychological, and cognitive ...
Jonathan Stewart +8 more
semanticscholar +1 more source
A neutrophil activation signature predicts critical illness and mortality in COVID-19
Blood Advances, 2021 Pathologic immune hyperactivation is emerging as a key feature of critical illness in COVID-19, but the mechanisms involved remain poorly understood.
Matthew L. Meizlish +29 more
semanticscholar +1 more source
Critical Care, 2023 Objective To evaluate the safety, feasibility, and efficacy of combined adrenergic blockade with propranolol and clonidine in patients with severe traumatic brain injury (TBI).
Mina F. Nordness +16 more
doaj +1 more source
British medical journal, 2020 Objective To describe outcomes of people admitted to hospital with coronavirus disease 2019 (covid-19) in the United States, and the clinical and laboratory characteristics associated with severity of illness. Design Prospective cohort study.
C. Petrilli +9 more
semanticscholar +1 more source
Genetic mechanisms of critical illness in COVID-19
Nature, 2020 Host-mediated lung inflammation is present1, and drives mortality2, in the critical illness caused by coronavirus disease 2019 (COVID-19). Host genetic variants associated with critical illness may identify mechanistic targets for therapeutic ...
E. Pairo-Castineira +65 more
semanticscholar +1 more source