Results 231 to 240 of about 6,560,806 (389)

Prospective evaluation of a modified Early Warning Score to aid earlier detection of patients developing critical illness on a general surgical ward

, 2000
C. W. Stenhouse, Shirley Coates, M. Tivey, P. Allsop, Thomas H. Parker   +4 more
openalex   +1 more source

Tead1a Initiates Transcriptional Priming Through the TEAD1a/YAP‐Notch1‐Spi1/Cebpα Axis to Promote Neutrophil Fate

Advanced Science, EarlyView.
This study discovered that the protein TEAD1a is crucial for neutrophil development. In zebrafish models, disrupting TEAD1a or its interaction with partner protein YAP1 caused severe neutrophil deficiency. TEAD1a functions during the early HSC stage, activates Notch1 signaling in the GMP stage, and triggers Spi1 and Cebpα to drive neutrophil terminal ...
Wang Yiqin, Yang Ruimeng, Wang Peihong, Liu Xiaohui, Yuan Hao, Huang Hongli, Zhou Yongjian, Xie Baoshu   +7 more
wiley   +1 more source

The characteristics of patients given antidepressants while recovering from critical illness

, 2000
Christina Jones, Paul Skirrow, Richard Griffiths, Gerry Humphris, Shay Dawson, Jane Eddleston   +5 more
openalex   +1 more source

Critical illness polyneuropathy: clinical findings and cell culture assay of neurotoxicity assessed by a prospective study [PDF]

, 2001
A. Druschky, Matthias Herkert, Martin Radespiel‐Tröger, Katrin Druschky, Ernst Hund, Cord‐Michael Becker, Max J. Hilz, Frank Erbguth, B. Neundörfer   +8 more
openalex   +1 more source

ADAR1 as a Placental Innate Immune Rheostat Sustaining the Homeostatic Balance of Intrinsic Interferon Response at the Maternal‐Fetal Interface

Advanced Science, EarlyView.
This study reveals that ADAR1, an RNA‐editing enzyme, fine‐tunes immune responses in the placenta by preventing the accumulation of immunogenic double‐stranded RNAs (dsRNAs) from interferon‐stimulated genes. The loss of ADAR1 in the placenta leads to excessive interferon signaling restricted to the junctional zone, disrupting placental development and ...
Xiaogang Chen, Xiangchao Xu, Jiahao Chen, Huiru Zhang, Wanshan Zheng, Wenzhe Yu, Xiaoqian Hu, Bin Cao   +7 more
wiley   +1 more source

Advocating for the recognition of underlying immunosuppression in critical illness. [PDF]

EClinicalMedicine
Martin-Loeches I, David S, Pène F, Kreitmann L, Russel L, Puxty K, Silva JS, Mata AV, Creagh-Brown B, Castro P, Salluh J, Vidaur-Tello L, Nseir S, Azoulay E.   +13 more
europepmc   +1 more source

Heart rate variability displays 1/ f noise in critical illness and correlates with severity of multiple organ dysfunction

, 2000
SM Tibby, Helena Frndova, P. Cox
openalex   +1 more source

Reduced Red Cell 2,3-Diphosphoglycerate Concentrations in Critical Illness without Decreased in Vivo P50 [PDF]

, 2001
T. J. Morgan, David Koch, Danna K. Morris, Alan Clague, David M. Purdie   +4 more
openalex   +1 more source

Plasma Metabolic Profile with Machine Learning Reveals Distinct Diagnostic and Biological Signatures for Pathologic Myopia

Advanced Science, EarlyView.
Plasma metabolic detection combined with machine learning offers a precise (area under the curve of 0.874) and high‐throughput (<30 s) diagnosis for pathologic myopia (serious myopic macular degeneration). The biomarkers indicate the pathologic myopia‐associated systemic metabolic reprogramming, which exhibits specificity for myopic macular ...
Ziheng Qi, Jiao Qi, Ye Zhang, Yanhui Wang, Yuchen Feng, Zifan Yang, Yating Wang, Weikang Shu, Dongling Guo, Ching Kang, Keke Zhang, Yi Lu, Jingjing Wan, Xiangjia Zhu   +13 more
wiley   +1 more source

Post-resuscitation Critical Illness Dysphagia: A Case Report. [PDF]

Cureus
Hassan AMM, Shah S, Bustamante N, Solano J.   +3 more
europepmc   +1 more source