Results 21 to 30 of about 6,957,076 (388)

Endothelial Glycocalyx Degradation in Critical Illness and Injury

open access: yesFrontiers in Medicine, 2022
The endothelial glycocalyx is a gel-like layer on the luminal side of blood vessels that is composed of glycosaminoglycans and the proteins that tether them to the plasma membrane.
E. Patterson, G. Cepinskas, D. Fraser
semanticscholar   +1 more source

Chronic Critical Illness [PDF]

open access: yesAmerican Journal of Respiratory and Critical Care Medicine, 2010
Although advances in intensive care have enabled more patients to survive an acute critical illness, they also have created a large and growing population of chronically critically ill patients with prolonged dependence on mechanical ventilation and other intensive care therapies.
Judith E, Nelson   +3 more
openaire   +2 more sources

Voluntary running exercise protects against sepsis-induced early inflammatory and pro-coagulant responses in aged mice

open access: yesCritical Care, 2017
Background Despite many animal studies and clinical trials, mortality in sepsis remains high. This may be due to the fact that most experimental studies of sepsis employ young animals, whereas the majority of septic patients are elderly (60 − 70 years ...
Karel Tyml   +7 more
doaj   +1 more source

Influence of Limonin on Malignant Biological Behavior of Non-small Cell Lung Cancer Cells by Regulating JAK2/STAT3 Signaling Pathway

open access: yesZhongliu Fangzhi Yanjiu, 2023
Objective To investigate the influence of limonin on the malignant biological behavior of non-small cell lung cancer (NSCLC) cells by regulating the protein tyrosine kinase 2 (JAK2)/signal transducer and activator of transcription 3 (STAT3) signaling ...
HU Huijie, ZHENG Xiaolu, LEI Lifeng
doaj   +1 more source

Factors associated with hospitalization and critical illness among 4,103 patients with COVID-19 disease in New York City

open access: yesmedRxiv, 2020
Background: Little is known about factors associated with hospitalization and critical illness in Covid-19 positive patients. Methods: We conducted a cross-sectional analysis of all patients with laboratory-confirmed Covid-19 treated at a single academic
C. Petrilli   +9 more
semanticscholar   +1 more source

Long-term outcomes after critical illness: recent insights

open access: yesCritical Care, 2021
Intensive care survivors often experience post-intensive care sequelae, which are frequently gathered together under the term “post-intensive care syndrome” (PICS).
A. Rousseau   +10 more
semanticscholar   +1 more source

Critical illness polyneuromyopathy [PDF]

open access: yesCanadian Medical Association Journal, 2016
Flaccid weakness develops in the limbs or respiratory muscles; the latter may present as difficulty in weaning from ventilation. Sensation may be reduced to pinprick. Reflexes may be present in the acute phase of the illness but are generally reduced or absent.
Cameron, Cunningham, Heather, Finlayson
openaire   +2 more sources

Antimicrobial exposure and the risk of delirium in critically ill patients

open access: yesCritical Care, 2018
Background Prior retrospective cross-sectional work has associated antimicrobials with a non-specific phrase: encephalopathy without seizures. The purpose of this study is to determine whether different classes of antimicrobials have differential ...
Jessica J. Grahl   +8 more
doaj   +1 more source

AKI patients have worse long-term outcomes, especially in the immediate post-ICU period [PDF]

open access: yes, 2012
Acute kidney injury (AKI) is associated with worse outcome in the acute phase of acute illness but also in the chronic phase. In a large Danish study in this issue of Critical Care, 1-year mortality was higher in patients with AKI than in patients ...
De Corte, Wouter, Hoste, Eric
core   +2 more sources

Glucocorticoids and the Brain after Critical Illness

open access: yesEndocrinology, 2021
Treatment for critical illness typically focuses on a patient’s short-term physical recovery; however, recent work has broadened our understanding of the long-term implications of illness and treatment strategies.
Alice R Hill, Joanna L. Spencer-Segal
semanticscholar   +1 more source

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