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Stem-cell therapies in critical limb ischemia [PDF]

open access: yesThe Moldovan Medical Journal, 2021
Background: Due to stimulation of muscular regeneration in ischemic extremities and increasing blood flow, stem cells are considered a promising new strategy for patients with critical limb ischemia (CLI).
Sergiu Visnevschi   +3 more
doaj   +1 more source

Patients with critical limb ischemia (CLI) not suitable for revascularization: the “dark side” of CLI

open access: yesVascular Investigation and Therapy, 2021
Critical limb ischemia (CLI) is the most advanced stage of peripheral arterial disease (PAD). Its prognosis is poor, with high rates of limb amputation and cardiovascular mortality.
Romeo Martini, Francesca Ghirardini
doaj   +1 more source

Free Flap Salvage in the Ischemic Foot: A Case Report

open access: yesArchives of Plastic Surgery, 2022
We performed distal bypass and free flap transfer in a single-stage operation to repair an extensive soft tissue defect in an ischemic foot of an 84-year-old woman.
Dongkyung Seo   +6 more
doaj   +1 more source

Upper limb ischemia in a newborn following difficult delivery

open access: yesJournal of Pediatric Surgery Case Reports, 2020
Neonatal limb ischemia is a very rare condition. The lower limb ischemia is more common than upper limb ischemia in incidence. The limb ischemia in such an age group urges for top urgent proper management.
Drkamal alzoghby   +3 more
doaj   +1 more source

Modern methods of stimulation of angiogenesis in patients with critical limb ischemia (review)

open access: yesJournal of Education, Health and Sport, 2017
The term "critical ischemia of extremities" (critical limb ischemia) was first introduced by P.R.F. Bell in 1982 to refer to a group of diseases accompanied by pain in the legs at rest, trophic ulcers and distal necroses of the lower limbs.
I. A. Kryvoruchko   +6 more
doaj   +3 more sources

Crossing complex infrapopliteal lesions utilizing a front-end cutting technique: A report of two cases with a novel rotational atherectomy device

open access: yesSAGE Open Medical Case Reports, 2023
Critical limb ischemia represents the most severe stage of peripheral vascular disease and patients often present with complex, calcified infrapopliteal lesions.
Siddhartha Rao   +4 more
doaj   +1 more source

Combination of Antioxidant Enzyme Overexpression and N‐Acetylcysteine Treatment Enhances the Survival of Bone Marrow Mesenchymal Stromal Cells in Ischemic Limb in Mice With Type 2 Diabetes

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Therapy with mesenchymal stem cells remains a promising but challenging approach to critical limb ischemia in diabetes because of the dismal cell survival.
Qiang Zhu   +13 more
doaj   +1 more source

Endothelial Progenitor Cells May Be Related to Major Amputation after Angioplasty in Patients with Critical Limb Ischemia

open access: yesCells, 2023
Background: Critical limb ischemia represents an advanced stage of peripheral arterial disease. Angioplasty improves blood flow to the limb; however, some patients progress irreversibly to lower limb amputation.
Daniel Santillán-Cortez   +15 more
doaj   +1 more source

Limb salvage following below-the-ankle angioplasty in critical limb ischemia

open access: yesIndian Journal of Vascular and Endovascular Surgery, 2020
Aim: The aim was to report limb salvage following below-the-ankle (BTA) angioplasty as an adjunct to proximal angioplasty in patients with critical limb ischemia (CLI).
B Nishan   +4 more
doaj   +1 more source

Endovascular treatment of critical lower limb ischemia caused by giant cell arteritis

open access: yesJournal of Vascular Surgery Cases and Innovative Techniques, 2019
Giant cell arteritis (GCA) is a well-known cause of cranial vasculitis often presenting with headache and jaw claudication. Here we report the case of a woman suffering GCA who presented with critical lower limb ischemia.
Rohan H.P. McLachlan, MD, BMS   +3 more
doaj   +1 more source

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