Improved arteriogenesis with simultaneous skeletal muscle repair in ischemic tissue by SCL plus multipotent adult progenitor cell clones from peripheral blood [PDF]
Background: The CD34- murine stem cell line RM26 cloned from peripheral blood mononuclear cells has been shown to generate hematopoietic progeny in lethally irradiated animals.
Gottgens, Berthold +7 more
core +1 more source
Background Elderly populations are susceptible to critical limb ischemia (CLI), but conventional treatments cannot significantly decrease amputation and mortality. Although exercise is an effective “non-pharmacological medicine” targeting mitochondria to
Wuyang He +3 more
semanticscholar +1 more source
Therapeutic Angiogenesis for Severely Ischemic Limbs — from Bench to Bedside in Acute Vascular Care
Severe limb ischemia represents a critical condition, being associated with high morbidity and mortality rates. Patients with critical limb ischemia (CLI) require urgent initiation of interventional or surgical treatment, as restoration of the blood flow
Benedek Theodora +2 more
doaj +1 more source
Review: Quality of Life in Lower Limb Peripheral Vascular Surgery [PDF]
PURPOSE: Vascular intervention studies generally consider patency and limb salvage as primary outcomes. However, quality of life is increasingly considered an important patient-oriented outcome measurement of vascular interventions.
Basto Gonçalves, F +6 more
core +1 more source
The effect of different positions on lower limbs skin perfusion pressure
We have encountered situations of patients with critical limb ischemia accompanied by pain at rest and necrosis, who hang their legs down from the bed during sleep.
Tota Kawasaki +6 more
doaj +1 more source
Arteriogenesis versus angiogenesis: similarities and differences [PDF]
Cardiovascular diseases account for more than half of total mortality before the age of 75 in industrialized countries. To develop therapies promoting the compensatory growth of blood vessels could be superior to palliative surgical surgical ...
Eitenmüller, Inka +3 more
core +1 more source
S-allylcysteine Improves Blood Flow Recovery and Prevents Ischemic Injury by Augmenting Neovasculogenesis. [PDF]
Studies suggest that a low level of circulating human endothelial progenitor cells (EPCs) is a risk factor for ischemic injury and coronary artery disease (CAD). Consumption of S-allylcysteine (SAC) is known to prevent CAD.
Chao, Che-Yi +7 more
core +1 more source
Sex Differences in Management and Outcomes of Critical Limb Ischemia in the Medicare Population
Supplemental Digital Content is available in the text. Background: Evidence about sex differences in management and outcomes of critical limb ischemia (CLI) is conflicting.
A. Mentias +3 more
semanticscholar +1 more source
Hypertensive extracorporeal limb perfusion for critical limb ischemia [PDF]
This article reports the early results in humans of hypertensive extracorporeal limb perfusion (HELP) technology in the prevention of major limb amputation due to ischemia. The short-term aim was to dilate pre-existing collateral channels, and the long-term aim was to stimulate remodeling and new collateral development by increasing endothelial shear ...
Darryl McMillan +7 more
openaire +3 more sources
Retrograde access is an alternative approach to endovascular intervention for critical limb ischemia but may be challenging in patients with poor below-knee vessel runoff.
Weifeng Lu, MD +3 more
doaj +1 more source

