Results 41 to 50 of about 98,922 (352)

Application of autologous hemopoietic stem cells in inoperable patients with chronic critical lower limb ischemia

Вестник хирургии имени И.И. Грекова, 2022
The OBJECTIVE was to study the efficiency of transplantation of autologous hematopoietic stem cells in patients with chronic critical lower limb ischemia and compare the results of treatment depending on the number of their transplantations.METHODS AND ...
I. P. Mikhaylov, N. V. Borovkova, N. E. Kudrjashova, B. V. Kozlovskij, I. N. Ponomarjov, O. V. Leshсhinskaja   +5 more
doaj   +1 more source

Using the epidemiology of critical limb ischemia to estimate the number of patients amenable to endovascular therapy

Vascular Medicine, 2020
Critical limb ischemia represents the advanced stage of peripheral artery disease, a health problem with increasing prevalence. Critical limb ischemia is associated with significant mortality, limb loss, pain, and diminished health-related quality of ...
A. Fereydooni, J. Gorecka, A. Dardik
semanticscholar   +1 more source

Gangrene, revascularization, and limb function improved with E-selectin/adeno-associated virus gene therapy

JVS - Vascular Science, 2021
Objective: Novel therapeutic angiogenic concepts for critical limb ischemia are still needed for limb salvage. E-selectin, a cell-adhesion molecule, is vital for recruitment of the stem/progenitor cells necessary for neovascularization in ischemic ...
Hallie J. Quiroz, MD, Punam P. Parikh, MD, Roberta M. Lassance-Soares, PhD, Manuela M. Regueiro, PhD, Yan Li, PhD, Hongwei Shao, PhD, Roberto Vazquez-Padron, PhD, Justin Percival, PhD, Zhao-Jun Liu, MD, PhD, Omaida C. Velazquez, MD   +9 more
doaj   +1 more source

Current Status of Cell-Based Therapy in Patients with Critical Limb Ischemia

International Journal of Molecular Sciences, 2020
(1) Background: The treatment of peripheral arterial disease (PAD) is focused on improving perfusion and oxygenation in the affected limb. Standard revascularization methods include bypass surgery, endovascular interventional procedures, or hybrid ...
F. Jalůvka, P. Ihnát, J. Madaric, A. Vrtková, J. Janošek, V. Procházka   +5 more
semanticscholar   +1 more source

Perfusion Assessment in Critical Limb Ischemia: Principles for Understanding and the Development of Evidence and Evaluation of Devices: A Scientific Statement From the American Heart Association.

Circulation, 2019
There are >12 million patients with peripheral artery disease in the United States. The most severe form of peripheral artery disease is critical limb ischemia (CLI). The diagnosis and management of CLI is often challenging.
S. Misra, M. Shishehbor, E. Takahashi, H. Aronow, L. Brewster, M. Bunte, E. Kim, J. Lindner, K. Rich   +8 more
semanticscholar   +1 more source

Characteristics and Outcome for Persons with Diabetic Foot Ulcer and No-Option Critical Limb Ischemia

Journal of Clinical Medicine, 2020
The study aimed to evaluate clinical and vascular characteristics, as well as outcomes, for diabetic persons with foot ulceration and no-option critical limb ischemia (CLI). The study group included a sample of patients admitted to our diabetic foot unit
M. Meloni, V. Izzo, V. Da Ros, D. Morosetti, M. Stefanini, E. Brocco, L. Giurato, R. Gandini, L. Uccioli   +8 more
semanticscholar   +1 more source

Noncoding RNAs in Critical Limb Ischemia

Arteriosclerosis, Thrombosis and Vascular Biology, 2020
Peripheral artery disease, caused by chronic arterial occlusion of the lower extremities, affects over 200 million people worldwide. Peripheral artery disease can progress into critical limb ischemia (CLI), its more severe manifestation, which is ...
D. Pérez-Cremades, Henry S. Cheng, M. W. Feinberg   +2 more
semanticscholar   +1 more source

Hypertensive extracorporeal limb perfusion for critical limb ischemia [PDF]

Journal of Vascular Surgery, 2013
This article reports the early results in humans of hypertensive extracorporeal limb perfusion (HELP) technology in the prevention of major limb amputation due to ischemia. The short-term aim was to dilate pre-existing collateral channels, and the long-term aim was to stimulate remodeling and new collateral development by increasing endothelial shear ...
Khin, Nyan Y., Dijkstra, Martijn L., Huckson, Matt, Phillips, Mark, McMillan, Darryl, Itoh, Seiji, Roger, Greg, Lane, Rodney J.   +7 more
openaire   +2 more sources

Post‐COVID Fatigue Is Associated With Reduced Cortical Thickness After Hospitalization

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuropsychiatric symptoms are among the most prevalent sequelae of COVID‐19, particularly among hospitalized patients. Recent research has identified volumetric brain changes associated with COVID‐19. However, it currently remains poorly understood how brain changes relate to post‐COVID fatigue and cognitive deficits.
Tim J. Hartung, Florentin Steigerwald, Amy Romanello, Cathrin Kodde, Matthias Endres, Sandra Frank, Peter Heuschmann, Philipp Koehler, Stephan Krohn, Daniel Pape, Jens Schaller, Sophia Stöcklein, Istvan Vadasz, Janne Vehreschild, Martin Witzenrath, Thomas Zoller, Carsten Finke, on behalf of the NAPKON Study Group, Y. Ahlgrimm, C. Finke, J. Fricke, T. Keil, L. Krist, N. Lisewsky, M. Mittermaier, M. Mueller‐Plathe, C. Pley, S. Schmidt, A. Stege, F. Steinbeis, S. Steinbrecher, C. Wildberg, M. Witzenrath, E. Zessin, T. Zoller, C. Arendt, C. Bellinghausen, S. Cremer, A. Groh, A. Gruenewaldt, Y. Khodamoradi, S. Klinsing, G. Rohde, M. Vehreschild, T. Vogl, S. Frank, J. C. Hellmuth, M. Huber, S. Kaeaeb, O. T. Keppler, E. Khatamzas, C. Mandel, S. Mueller, M. Muenchhoff, L. Reeh, C. Scherer, H. Stubbe, M. von Bergwelt, L. Weiss, B. Zwissler, S. Cleef, M. E. Figuera Basso, J. Franzenburg, K. Franzpoetter, A. Friedrichs, A. Hermes, J. Heyckendorf, C. Kujat, I. Lehmann, C. Maetzler, S. Meier, D. Pape, S. Poick, L. Reinke, A. K. Russ, A. M. Scheer, D. Schunk, T. Tamminga, S. Bohnet, D. Droemann, K. F. Franzen, R. Hoerster, N. Kaeding, M. Nissen, P. Parschke, J. Rupp, S. Caesar, H. Einsele, S. Frantz, A. Frey, A. Grau, K. Haas, C. Haertel, K. G. Haeusler, G. Hein, J. Herrmann, A. Horn, R. Jahns, P. Meybohm, F. A. Montellano, C. Morbach, J. Schmidt, P. Schulze, S. Stoerk, J. Volkmann, T. Bahmer, A. Hermes, M. Krawczak, W. Lieb, S. Schreiber, T. Tamminga, B. Balzuweit, S. Berger, J. Fricke, M. Hummel, A. Krannich, L. Krist, F. Kurth, J. Lienau, R. Lorbeer, C. Pley, J. Schaller, S. Schmidt, C. Thibeault, M. Witzenrath, T. Zoller, I. Bernemann, T. Illig, M. Kersting, N. Klopp, V. Kopfnagel, S. Muecke, M. Kraus, B. Lorenz‐Depiereux, G. Anton, A. Kuehn‐Steven, S. Kunze, M. K. Tauchert, K. Appel, M. Brechtel, I. Broehl, K. Fiedler, R. Geisler, S. M. Hopff, K. Knaub, C. Lee, S. Nunes de Miranda, S. Raquib, G. Sauer, M. Scherer, J. J. Vehreschild, P. Wagner, L. Wolf, J. C. Hellmuth, K. Guenther, F. Haug, J. Haug, A. Horn, M. Kohls, C. Fiessler, P. U. Heuschmann, O. Miljukov, C. Nuernberger, J. P. Reese, L. Schmidbauer, I. Chaplinskaya, S. Hanss, D. Krefting, C. Pape, M. Rainers, A. Schoneberg, N. Weinert, T. Bahls, W. Hoffmann, M. Nauck, C. Schaefer, M. Schattschneider, D. Stahl, H. Valentin, P. Heuschmann, A. L. Hofmann, S. Jiru‐Hillmann, J. P. Reese, S. Herold, P. Heuschmann, R. Heyder, W. Hoffmann, T. Illig, S. Schreiber, J. J. Vehreschild, M. Witzenrath   +190 more
wiley   +1 more source

Role of duplex-guided infragenicular angioplasty in saving limbs

Journal of the Arab Society for Medical Research, 2022
Background/aim Critical limb ischemia (CLI) is known as ischemic rest pain at rest or tissue loss with peripheral arterial disease. Endovascular intervention has many advantages than surgical bypasses and it is used frequently with fragile patients, at ...
Sameh E Elimam, Hala M Shereif
doaj   +1 more source