Results 61 to 70 of about 129,036 (402)

Noncoding RNAs in Critical Limb Ischemia

Arteriosclerosis, Thrombosis and Vascular Biology, 2020
Peripheral artery disease, caused by chronic arterial occlusion of the lower extremities, affects over 200 million people worldwide. Peripheral artery disease can progress into critical limb ischemia (CLI), its more severe manifestation, which is ...
D. Pérez-Cremades, Henry S. Cheng, M. W. Feinberg   +2 more
semanticscholar   +1 more source

Management of Critical Limb Ischemia [PDF]

Circulation: Cardiovascular Interventions, 2016
Critical limb ischemia (CLI) is a clinical syndrome of ischemic pain at rest or tissue loss, such as nonhealing ulcers or gangrene, related to peripheral artery disease. CLI has a high short-term risk of limb loss and cardiovascular events. Noninvasive or invasive angiography help determine the feasibility and approach to arterial revascularization. An
openaire   +2 more sources

Long term efficacy and safety of rivaroxaban plus cilostazol in the treatment of critical ischemia of the lower limbs in a frail, elderly patient with non valvular atrial fibrillation

Journal of Pharmaceutical Health Care and Sciences, 2020
Background Many patients with critical lower limb ischemia are not eligible for revascularization procedures. Still, given the emerging role of both platelet and coagulation activation in the formation of arterial thrombi, they may benefit from the novel
Antonio Trani, Pietro Benedetto, Ferdinando Di Leo, Angela Baiano, Andrea Esposito, Danilo Menna, Arianna Allegretti, Pierluigi Antonino Cappiello, Domenico Dell’Edera   +8 more
doaj   +1 more source

Trends in Hospitalization, Management, and Clinical Outcomes Among Veterans With Critical Limb Ischemia

Circulation. Cardiovascular Interventions, 2020
Supplemental Digital Content is available in the text. Background: Contemporary patterns in management and outcomes of critical limb ischemia among United States veterans are unknown.
A. Mentias, A. Qazi, Kimberly D. McCoy, R. Wallace, M. Vaughan-Sarrazin, S. Girotra   +5 more
semanticscholar   +1 more source

Critical Upper Limb Ischemia Due to Brachial Tourniquet in Misdiagnosed Thoracic Outlet Syndrome after Carpal Tunnel Decompression: A Case Report [PDF]

, 2017
We present the case of a 68-year-old woman, referred to our department for critical upper limb ischemia, which had occurred a few days after homolateral surgical ligamentotomy for carpal tunnel syndrome, diagnosed and confirmed by electromyography, and ...
Bassetto, Franco, Bonvini, Stefano, Monticelli, Andrea, Tiengo, Cesare, Venezia, Erica Dalla, Wassermann, Valentina   +5 more
core  

Reconstituted high-density lipoproteins promote wound repair and blood flow recovery in response to ischemia in aged mice [PDF]

, 2016
Background: The average population age is increasing and the incidence of age-related vascular complications is rising in parallel. Impaired wound healing and disordered ischemia-mediated angiogenesis are key contributors to age-impaired vascular ...
Bursill, Christina A., Lam, Yuen Ting, Ng, Martin K. C., Ridiandries, Anisyah, Robertson, Stacy, Tan, Joanne T. M., Tsatralis, Tania, Vanags, Laura Z.   +7 more
core   +2 more sources

Perfusion Assessment in Critical Limb Ischemia: Principles for Understanding and the Development of Evidence and Evaluation of Devices: A Scientific Statement From the American Heart Association.

Circulation, 2019
There are >12 million patients with peripheral artery disease in the United States. The most severe form of peripheral artery disease is critical limb ischemia (CLI). The diagnosis and management of CLI is often challenging.
S. Misra, M. Shishehbor, E. Takahashi, H. Aronow, L. Brewster, M. Bunte, E. Kim, J. Lindner, K. Rich   +8 more
semanticscholar   +1 more source

Being BOLD in Critical Limb Ischemia ∗

Journal of the American College of Cardiology, 2016
“Begin, be bold, and venture to be wise.”— Horace [(1)][1] The management of peripheral arterial disease (PAD) still heavily relies on clinical judgment and the use of the ankle-brachial pressure index (ABPI), originally described in 1950 for the noninvasive diagnosis of lower ...
Taehoon Shin, Sanjay Rajagopalan
openaire   +3 more sources

Central Dysmyelination in SSADH‐Deficient Humans and Mice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Succinic semialdehyde dehydrogenase deficiency (SSADHD) is an inherited metabolic disorder characterized by an accumulation of γ‐aminobutyric (GABA). In addition to its synaptic role as an inhibitory neurotransmitter, GABA also plays an important role in myelination.
Itay Tokatly Latzer, Henry H. C. Lee, Edward Yang, Cesar Alves, Mariarita Bertoldi, Caitlyn Fung, Spencer V. Steele, Eren Kule, Zijie Jin, Alexander Rotenberg, Jean‐Baptiste Roullet, Phillip L. Pearl   +11 more
wiley   +1 more source

Transducer Materials Mediated Deep Brain Stimulation in Neurological Disorders

Advanced Functional Materials, EarlyView.
This review discusses advanced transducer materials for improving deep brain stimulation (DBS) in neurological disorders. These materials respond to light, ultrasound, or magnetic fields, enabling precise, less invasive neuromodulation. Their stimulus‐responsive properties enhance neural control and adaptive therapy, paving the way for next‐generation ...
Di Zhao, Zhengyang Cao, Guangjun Zhong, Limin Shi, Junxia Xie, Jianhua Hao   +5 more
wiley   +1 more source