Results 81 to 90 of about 129,036 (402)

Immunomodulation With Local, Sustained Delivery of Pituitary Adenylate Cyclase Activating Polypeptide Results in Improved Functional Recovery in Stroke‐Injured Mice

Advanced Healthcare Materials, EarlyView.
The tissue and functional benefits are demonstrated with local, sustained delivery of an anti‐inflammatory peptide, pituitary adenylate cyclase‐activating polypeptide (PACAP), for stroke treatment in a mouse model. Prolonged PACAP treatment modulated astrocyte and microglia toward pro‐reparative phenotypes, enhanced neuroprotection and preservation of ...
Eric Ho, David Xinzheyang Li, Hong Cui, Dania Akbar, Ricky Siu, Cindi M. Morshead, David Chatenet, Molly S. Shoichet   +7 more
wiley   +1 more source

Involvement of leukotriene pathway in the pathogenesis of ischemia-reperfusion injury and septic and non-septic shock. [PDF]

, 2009
The 5-lipoxygenase (5-LO) pathway is responsible for the production of leukotrienes (LTs), inflammatory lipid mediators which play a role in innate immunity. More recently, a pivotal role of LTs in ischemia-reperfusion and shock injury has been suggested.
CUZZOCREA S, ROSSI, ANTONIETTA, SAUTEBIN, LIDIA   +2 more
core   +1 more source

Roll‐To‐Roll Production of Smart Dressings for Wound Monitoring

Advanced Healthcare Materials, EarlyView.
This study presents a roll‐to‐roll manufactured smart wound dressing capable of visually monitoring key wound biomarkers, including pH, humidity, and temperature. By integrating colorimetric sensors into flexible dressing substrates, the device offers real‐time, equipment‐free insights for infection detection and wound management, representing a ...
Ziheng Wang, Yujin Ahn, Semin Kwon, Tianhao Yu, Yumin Dai, Julia Walsh, Joo Hun Lee, Sang Mok Park, Seul Ah Lee, Murtuza Peerbhai, Chandan K. Sen, Hyowon Lee, Young L. Kim, Hyunjoon Kong, Chi Hwan Lee   +14 more
wiley   +1 more source

E-Selectin/AAV2/2 Gene Therapy Alters Angiogenesis and Inflammatory Gene Profiles in Mouse Gangrene Model

Frontiers in Cardiovascular Medicine, 2022
For patients with chronic limb-threatening ischemia and limited revascularization options, alternate means for therapeutic angiogenesis and limb salvage are needed.
Antoine J. Ribieras, Yulexi Y. Ortiz, Yan Li, Carlos T. Huerta, Nga Le, Hongwei Shao, Roberto I. Vazquez-Padron, Roberto I. Vazquez-Padron, Zhao-Jun Liu, Zhao-Jun Liu, Omaida C. Velazquez, Omaida C. Velazquez   +11 more
doaj   +1 more source

Spatiotemporal release of VEGF from biodegradable polylactic-co-glycolic acid microspheres induces angiogenesis in chick chorionic allantoic membrane assay [PDF]

, 2019
The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.While vascular endothelial growth factor (VEGF) is an acknowledged potent pro-angiogenic agent there is a ...
Bullock, Anthony J., Gigliobianco, Giulia, MacNeil, Sheila, Qutachi, Omar   +3 more
core   +1 more source

Microscopically Adaptable Bioink Guide Cell Compartmentalization toward Morphogenesis of a Functional Vasculature‐Like System

Advanced Healthcare Materials, EarlyView.
Contractile vasculatures are fabricated through a one‐step bioprinting strategy. The adaptable microenvironment provided by ECM‐mimicking bioink triggers cell sorting and compartmentalization of endothelial cells and vascular smooth muscle cells toward a histological configuration by focal adhesion kinase‐mediated upregulation of cell adhesion and ...
Jun Chen, Yuqiong Wu, Jiarong Huang, Junjin Jie, Chan Huang, Di Zhang, Yuxin Huang, Rui Mao, Ming Zhao, Lin‐Ping Wu   +9 more
wiley   +1 more source

Endovascular Treatment of Acute Tibioperoneal Trunk Thrombosis. A Clinical Case Report

Креативная хирургия и онкология, 2019
Introduction. Acute limb ischemia is a severe disorder caused by a sharp drop in the arterial perfusion of the limb. It carries a threat to the limb’s function and viability.
D. S. Chigidinova, B. A. Rudenko, A. S. Shanoyan, V. P. Mazaev, F. B. Shukurov   +4 more
doaj   +1 more source

Duplex and Angiographic-Assisted Evaluation of Outcomes of Endovascular Embolization after Surgical Deep Vein Arterialization for the Treatment No-Option Critical Limb Ischemia Patients

Diagnostics, 2022
Objective: To report early and mid-term outcomes of the arterialization of the deep venous system in no-option critical limb-threatening ischemia (CLTI) using duplex ultrasound and angiographic evaluation to improve limb perfusion.
Nunzio Montelione, Vincenzo Catanese, Teresa Gabellini, Francesco Alberto Codispoti, Antonio Nenna, Francesco Spinelli, Francesco Stilo   +6 more
doaj   +1 more source

Functional outcome of critical limb ischemia [PDF]

Journal of Vascular Surgery, 2007
Results of treatment for critical limb ischemia have traditionally focused on physician-oriented end points related to limb salvage surgery. Although numerous studies have demonstrated excellent patency and limb salvage after surgical revascularization procedures, survival in this patient population is poor, comorbidities reducing quality of life are ...
openaire   +3 more sources

Choroid Plexus Fibroblast–ILC2 Niche Promotes Adult Hippocampal Neurogenesis after Traumatic Brain Injury

Advanced Science, EarlyView.
This study investigates the role of group 2 innate lymphoid cells (ILC2) in the choroid plexus (ChP) following traumatic brain injury (TBI). ILC2 accumulation alleviates immune infiltration, preserves hippocampal integrity, and improves sensory‐motor and memory functions.
Shiqi Gao, Xiaoming Guo, Sixuan Tian, Huaping Huang, Caidi Ying, Junjie Wang, Jiahao Zhang, Jun Lin, Anwen Shao, Jingyu Wang, Yuan Hong   +10 more
wiley   +1 more source