Results 141 to 150 of about 18,104 (240)
PLoS Pathogens, 2016 Yersinia outer protein M (YopM) is a crucial immunosuppressive effector of the plaque agent Yersinia pestis and other pathogenic Yersinia species. YopM enters the nucleus of host cells but neither the mechanisms governing its nucleocytoplasmic shuttling ...
Laura Berneking +14 more
doaj +1 more source
Nucleocytoplasmic transport: taking an inventory [PDF]
, 2018 In eukaryotic cells, the enclosure of the genetic information in the nucleus allows the spatial and temporal separation of DNA replication and transcription from cytoplasmic protein synthesis.
Fried, H., Kutay, U.
core
Trans-chalcone increases p53 activity via DNAJB1/HSP40 induction and CRM1 inhibition
PLoS ONE, 2018 Naturally-occurring chalcones and synthetic chalcone analogues have been demonstrated to have many biological effects, including anti-inflammatory, anti-malarial, anti-fungal, and anti-oxidant/anti-cancerous activities. Compared to other chalcones, trans-
Gabriel Silva +13 more
semanticscholar +1 more source
TNF stimulates nuclear export and secretion of IL-15 by acting on CRM1 and ARF6.
PLoS ONE, 2013 Interleukin (IL)-15 is a ubiquitously expressed cytokine that in the basal state is mainly localized intracellularly, including the nucleus. Unexpectedly, tumor necrosis factor-α (TNF) time-dependently induced nuclear export of IL-15Rα and IL15.
Suidong Ouyang +3 more
doaj +1 more source
PLoS ONE, 2015 Molecular traffic between the nucleus and the cytoplasm is regulated by the nuclear pore complex (NPC), which acts as a highly selective channel perforating the nuclear envelope in eukaryotic cells.
Seyed Hanif Mahboobi +2 more
doaj +1 more source
BMC Cancer, 2011 Background In ovarian cancer, the reported rate of EGFR expression varies between 4-70% depending on assessment method and data on patient outcome are conflicting.
Braicu Elena I +9 more
doaj +1 more source
Voting and Nonlinear Taxes in a Stylized Representative Democracy [PDF]
, 2003 We derive median-voter results and study the shape of redistributional taxes when voters elect a candidate who imposes taxes to maximize own utility. Under general conditions, a median-productivity candidate is a Condorcet winner.
Bohn, Henning, Stuart, Charles
core
Inter-cellular transport of ran GTPase.
PLoS ONE, 2015 Ran, a member of the Ras-GTPase superfamily, has a well-established role in regulating the transport of macromolecules across the nuclear envelope (NE). Ran has also been implicated in mitosis, cell cycle progression, and NE formation. Over-expression of
Deepak Khuperkar +3 more
doaj +1 more source
Voting and Nonlinear Taxes in a Stylized Representative Democracy [PDF]
We derive median-voter results and study the shape of redistributional taxes when voters elect a candidate who imposes taxes to maximize own utility. Under general conditions, a median-productivity candidate is a Condorcet winner.
Charles Stuart, Henning Bohn
core
Using Protege for automatic ontology instantiation [PDF]
, 2004 This paper gives an overview on the use of Protégé in the Artequakt system, which integrated Protégé with a set of natural language tools to automatically extract knowledge about artists from web documents and instantiate a given ontology.
Alani, Harith +6 more
core