Results 131 to 140 of about 3,056 (192)

GSK3/CRMP2 signaling confers PTEN knockout mediated axonal regeneration

Acta Ophthalmologica, 2019
AbstractKnockout of phosphatase and tensin homolog (PTEN‐/‐) is neuroprotective and promotes axon regeneration in mature neurons. Elevation and maintenance of mTOR activity in injured neurons have been proposed as the main underlying mechanism. Here we demonstrate that PTEN‐/‐ also abrogates the inhibitory activity of GSK3 on collapsin response ...
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前腹側脳室周囲核における性差発現タンパク質の探索と機能解析 [PDF]

, 2014
筑波大学 (University of Tsukuba ...
Iwakura Takashi, 岩倉 聖
core  

TNiK Is Required for Postsynaptic and Nuclear Signaling Pathways and Cognitive Function [PDF]

, 2012
Afinowi, Nurudeen O., Bussey, Timothy J., Coba, Marcelo P., Elsegood, Kathryn A., Fricker, David G., Grant, Seth G. N., Indersmitten, Tim, Komiyama, Noboru H., Kopanitsa, Maksym V., Nithianantharajah, Jess, O'Dell, Thomas J., Saksida, Lisa M., Skene, Nathan G., Stanford, Lianne E., Tuck, Ellie J.   +14 more
core   +1 more source

Structural basis for CRMP2-induced axonal microtubule formation

Structural basis for CRMP2-induced axonal microtubule formation
Microtubule associated protein Collapsin response mediator protein 2 (CRMP2) regulates neuronal polarity in developing neurons through interactions with tubulins or microtubules. However, how CRMP2 promotes axonal formation by affecting microtubule behavior remains unknown.
openaire  

Suppression of Glial Activation in Tau Transgenic Mice Through Inhibition of CRMP2 Phosphorylation: a Morphometric Analysis. [PDF]

Neuromolecular Med
Li W, Kubota T, Guevara VA, Goshima Y, Saido TC, Ohshima T.   +5 more
europepmc   +1 more source

Baishaoluoshi Decoction Mitigates Post-Stroke Spasticity by Targeting Synaptic Plasticity Through the Nogo-A/NgR Signaling Pathway. [PDF]

Brain Behav
Sun X, Zeng S, Lin S, Wu L, Tang X, Zhu J, Zhang Y, Li L, Chen Z, Deng X, Wu D, Xie L.   +11 more
europepmc   +1 more source

Cortical transcriptome analysis after spinal cord injury in Crmp2 ki/ki mice and mitochondrial behavior regulated by CRMP2

Cortical transcriptome analysis after spinal cord injury in Crmp2 ki/ki mice and mitochondrial behavior regulated by CRMP2
早大学位記番号 ...
openaire  

Lacosamide Is a Novel Drug That Improves AGTPBP1 Knockout-Mediated Impairment of Neuronal and Dopaminergic Function. [PDF]

Mol Neurobiol
Wang HP, Singh S, Wong LC, Hsu CJ, Li SC, Lee SJ, Lee CH, Lee WT.   +7 more
europepmc   +1 more source

CRMP2 phosphorylation regulates polarization and spinal infiltration of CD4 + T lymphocytes, inhibits spinal glial activation, and arthritic pain. [PDF]

Pain
Jiang YP, Wen JJ, Ma X, Yuan CR, Zhou F, Zheng MJ, Tang X, Yu XK, Lai WD, Zhou YH, Yu WH, You WT, Jin Y, Park KD, Khanna R, Wen CP, Yu J.   +16 more
europepmc   +1 more source

Pathogenic mechanisms of amyotrophic lateral sclerosis-linked VAPB P56S mutation in the degeneration of corticospinal motor neurons. [PDF]

Ageing Neurodegener Dis
Yang X, Zheng J, Wang X, Cai H, Yu J.
europepmc   +1 more source