, 2018 Crocetin, the major carotenoid in saffron, exhibits potent anticancer effects. However, the antileukemic effects of crocetin are still unclear, especially in primary acute promyelocytic leukemia (APL) cells.
Ghorbani, A. +10 more
core
Trans-crocetin improves amyloid-beta degradation in monocytes from Alzheimer's Disease patients
, 2017 Herbal medicines have been recently employed in research and clinical studies for the potential treatment of behavioral and psychological symptoms associated with Alzheimer's Disease (AD) and other types of dementia.
Del Pino AM +10 more
core +1 more source
Inhibition of tumor promotion in benzo a pyrene-initiated CD-1 mouse skin by crocetin
, 2009 The effects of topical application of crocetin on 12-O-tetradecanoylphorbol-13-acetate (TPA)- induced promotion of skin tumors, hyperplasia, hydrogen peroxide, ornithine decarboxylase (ODC ) and inflammation were evaluated in female CD-1 mice.
WANG, CHAU-JONG;LEE, MIAN-JANE;CHANG, MING-CHENG;LIN, JEN-KUN +1 more
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Crocetin reduces TNBS-induced experimental colitis in mice by downregulation of NFkB
The Saudi Journal of Gastroenterology, 2009 Background/Aim: Ulcerative colitis (UC) is characterized by oxidative and nitrosative stress, leukocyte infiltration and upregulation of proinflammatory cytokines. In this study, we aim to investigate the effects of crocetin and its protective mechanism
Kazi Hamid, Qian Zhiyu
doaj
Enhancing bioavailability of crocetin via encapsulation in nano-emulsion
, 2018 前人研究藏紅花酸 (crocetin) 具有多種生物活性例如：增強氧擴散速率、抗氧化、抗發炎、抗高血壓、抗血栓、抗動脈粥狀硬化、抑制視網膜損傷和改善睡眠質量。雖然藏紅花酸具有許多生物活性，但藏紅花酸難溶於水造成口服藏紅花低的生物可利用率。因此開發適合藏紅花酸包埋的方法來提高生物可利用率。 根據張銘聰博士所建立的包埋薑黃素和油體固定化的技術將此加以改良成適合藏紅花酸包埋的方法。形成水包油的 (O/W) 奈米乳液包埋 (encapsulation) 藏紅花酸，先將藏紅花酸分散於 Span ...
盧安祺, An-Chi Lu
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Crocetin Halts Tumorigenesis in Metastatic Breast Cancer via Disrupting CYP2J2/EET Axis. [PDF]
ACS OmegaManhas D +10 more
europepmc +1 more source
Evolutionary adaptation of CCD4 enzymes in <i>Buddleja alternifolia</i> for crocetin biosynthesis. [PDF]
Front Plant SciParreño E +6 more
europepmc +1 more source
Saffron as a Retinal Neuroprotectant: A Narrative Review of Preclinical Studies and Clinical Results. [PDF]
Antioxidants (Basel)Maggi MA +7 more
europepmc +1 more source
Dietary Carotenoid Intake and Sleep: A Narrative Review of Evidence from Human and In Vivo Animal Studies. [PDF]
NutrientsDudzik J, Weaver L, Jelic S, St-Onge MP.
europepmc +1 more source
The Therapeutic Use of Natural Products in Myopia Prevention: Recent Applications. [PDF]
Mol Nutr Food ResWang G, Ren C, Dong X, Zhao L, Guo B.
europepmc +1 more source