Bioconversion of carotenoids into high-value crocins using a marine sponge carotenoid cleavage dioxygenase. [PDF]
Summary Carotenoids and apocarotenoids are widespread specialized metabolites, yet animals, including sponges, lack the ability to synthesize carotenoids de novo and must obtain them from dietary or microbial sources. The roles of carotenoid cleavage dioxygenases (CCDs) in marine animals remain largely unexplored. A CCD from the marine sponge Suberites
Moreno-Giménez E +11 more
europepmc +2 more sources
Crocin Improves Damage Induced by Nicotine on A Number of Reproductive Parameters in Male Mice [PDF]
Background Crocin, a carotenoid isolated from Crocus sativus L. (saffron), is a pharmacologically active component of saffron. Nicotine consumption can decrease fertility in males through induction of oxidative stress and DNA damage.
Mohammad Reza Salahshoor +3 more
doaj +1 more source
Crocin (saffron bioactive) loaded protein nanoparticles were prepared from three underutilised cereal varieties viz., sorghum (SPCN), foxtail millet (FPCN) and pearl millet (PPCN) using ultrasonication technique.
Faiza Jhan +4 more
doaj +1 more source
In vivo and in vitro efficacy of crocin against Echinococcus multilocularis
Background Alveolar echinococcosis (AE) is a fatal zoonosis caused by the larvae of Echinococcus multilocularis. However, current chemotherapy treatment options are based on benzimidazoles [albendazole (ABZ) and mebendazole], which have limited efficacy.
Chuanchuan Liu +4 more
doaj +1 more source
Crocin’s effect on phenotype switching of J774A.1 macrophages depends on their polarization state during exposure [PDF]
Objective(s): Macrophages exhibit versatile phenotypes, with M1 macrophages releasing inflammatory cytokines and possessing microbicidal activities, while M2 macrophages release anti-inflammatory cytokines and contribute to tissue repair.
Hakimeh Abdi +4 more
doaj +1 more source
Short-Term, Cycle-Synchronized Adjunctive Therapy With Crocus Total Glucosides Tablets for Cardiac Protection Against Cancer Therapy-Related Cardiac Dysfunction in Breast Cancer Patients: A Randomized, Double-Blind, Placebo-Controlled Trial. [PDF]
Cycle‐synchronized CTGT therapy attenuates LVGLS decline and reduces CTRCD in breast cancer patients. This randomized, double‐blind, placebo‐controlled trial assessed whether cycle‐synchronized CTGT prevent CTRCD in 120 breast cancer patients receiving chemotherapy.
Liu X +11 more
europepmc +2 more sources
Renoprotective effect of crocin following liver ischemia/ reperfusion injury in Wistar rats [PDF]
Objective(s): The objectives of the current study were to evaluate the effects of hepatic ischemia/reperfusion (IR) injury on the activity of antioxidant enzymes, biochemical factors, and histopathological changes in rat kidney, and to investigate the ...
Seyyed Ali Mard +3 more
doaj +1 more source
Background: Stress affects brain functions and induces psychological disorders. Previous studies have indicated different effects of crocin and exercise on the improvement of memory in some types of stress.
Hajaralsadat Hosseini Dastgerdi +3 more
doaj +1 more source
Protective Effect of Crocin on Ovarian Ischemia-Reperfusion Injury in Rats [PDF]
Background & Aims: Ischemia-reperfusion (I-R) injury of the ovary may lead to ovarian injury. In this study, we investigated the protective effect of the crocin on ovarian I-R injury.
Masumeh Mohammadpour +1 more
doaj
The Effect of Eight Weeks Resistance Training with Two Doses of Crocin Consumption on Catalase and Glutathione Peroxidase in Kidney Tissue of Nandrolone Poisoned Rats [PDF]
Background & Objective: The use of anabolic steroids causes damage to various tissues, including the kidneys. Aim of present study was to investigate the effect of resistance training with consumption of crocin on catalase and glutathione peroxidase in ...
esfandiar heydari +2 more
doaj

