The effects of crocin nanoparticle on trace elements levels in paraquat-induced oxidative stress in rat [PDF]
Paraquat, a non-spesific herbicide, induces toxicity primarily through oxidative stress, with no specific antidote available. Evidence suggests paraquat disrupts ion homeostasis, affecting essential trace elements involved in antioxidant defense. Crocin,
Anahita Abbasifard +6 more
doaj +3 more sources
Background: Stress affects brain functions and induces psychological disorders. Previous studies have indicated different effects of crocin and exercise on the improvement of memory in some types of stress.
Hajaralsadat Hosseini Dastgerdi +3 more
doaj +3 more sources
Indirect Electrochemical Analysis of Crocin in Phytochemical Sample [PDF]
A new electroanalytical method has been developed for the quantitative determination of crocin in a sample of stigmas of saffron (Crocus sativus L.). Crocin is polarographically inactive.
Riyaz Ahmad Dar +3 more
doaj +2 more sources
The Therapeutic Effects of Crocus sativus L. and Its Constituents on the Improving Treatment of Azoospermia: A Narrative Review [PDF]
ABSTRACT Background and Aims Azoospermia, defined as the complete absence of sperm in the ejaculate, is a major cause of male infertility and is classified into obstructive and non‐obstructive forms. While obstructive azoospermia is primarily mechanical in origin, non‐obstructive azoospermia (NOA) is characterized by impaired spermatogenesis and is ...
Faraz Khakshour +4 more
wiley +2 more sources
Renoprotective effect of crocin following liver ischemia/ reperfusion injury in Wistar rats [PDF]
Objective(s): The objectives of the current study were to evaluate the effects of hepatic ischemia/reperfusion (IR) injury on the activity of antioxidant enzymes, biochemical factors, and histopathological changes in rat kidney, and to investigate the ...
Seyyed Ali Mard +3 more
doaj +2 more sources
The assembly of tetrameric human L‐lactate dehydrogenase is regulated by ionic strength, β‐NADH binding, cyclic peptides, and long‐chain dicarboxylates [PDF]
Abstract Lactate dehydrogenases catalyze the reduction of pyruvate to lactate, the generation of which is of importance for the energetic metabolism of malignant cells. In particular, human cancer cells overexpress lactate dehydrogenase A (hLDH‐A), whose catalytic activity depends on its assembly into the corresponding homotetramer (denoted as hLDH‐5),
Alessandra Stefan +7 more
wiley +2 more sources
RETRACTED: Crocin Inhibits Angiogenesis and Metastasis in Colon Cancer via TNF-α/NF-kB/VEGF Pathways [PDF]
Angiogenesis and metastasis play pivotal roles in the progression of cancer. We recently discovered that crocin, a dietary carotenoid derived from the Himalayan crocus, inhibited the growth of colon cancer cells.
Hamid A. Bakshi +9 more
doaj +2 more sources
Protective Effect of Crocin on Ovarian Ischemia-Reperfusion Injury in Rats [PDF]
Background & Aims: Ischemia-reperfusion (I-R) injury of the ovary may lead to ovarian injury. In this study, we investigated the protective effect of the crocin on ovarian I-R injury.
Masumeh Mohammadpour +1 more
doaj +2 more sources
Objective: The purpose of this study was to investigate the effects of Crocin on brain neuroterophins, cognition, sensory and motor dysfunction and compare to fingolimod effects in toxic-induced demyelination with Ethidium Bromide (EB) in female Wistar ...
Rouholah Fatemi +3 more
doaj +2 more sources
Evaluating the effect of crocin on contrast-induced nephropathy in rats [PDF]
Objective: Contrast-induced nephropathy (CIN) raises the risk of renal injury, but crocin, a saffron component, may improve kidney function. This study investigated crocin's protective effects against CIN in rats.Materials and Methods: Male Wistar rats ...
Mahnaz Zolfaghari Farajerdi +6 more
doaj +3 more sources

