Results 31 to 40 of about 5,332 (163)

The Effect of Eight Weeks Resistance Training with Two Doses of Crocin Consumption on Catalase and Glutathione Peroxidase in Kidney Tissue of Nandrolone Poisoned Rats [PDF]

Journal of Advanced Biomedical Sciences, 2019
Background & Objective: The use of anabolic steroids causes damage to various tissues, including the kidneys. Aim of present study was to investigate the effect of resistance training with consumption of crocin on catalase and glutathione peroxidase in ...
esfandiar heydari, ali hosseini, mohammad ali azarbayjani   +2 more
doaj  

Evaluation of the Effect of Crocin on Doxorubicin-Induced Cardiotoxicity

, 2021
Despite newer advances in cancer treatment, chemotherapy is still one of the most widely used treatment strategies in this field. However, this treatment strategy faces major challenges.
Hashem Khanbabaei, Alireza Farsinejad, Amirhossein Sahebkar, Pourghadamyari, Hossein, Arefeh Ghafari Novin, Nikzad, Amin, Khanbabaei, Hashem, Hossein Pourghadamyari, Farsinejad, Alireza, Mardani, Saba, Thozhukat Sathyapalan, Khoshandam, Mohadeseh, Sahebkar, Amirhossein, Sathyapalan, Thozhukat, Saba Mardani, Parisa Esmaili Motlagh, Fatemeh Ghahari, Motlagh, Parisa Esmaili, Mohadeseh Khoshandam, Novin, Arefeh Ghafari, Ghahari, Fatemeh, Amin Nikzad   +21 more
core   +1 more source

Antioxidant and anti-inflammatory potential of crocin on the doxorubicin mediated hepatotoxicity in Wistar rats

, 2023
Doxorubicin (DXR) is widely used in cancer treatment. However, it has not yet been possible to prevent the side effects of DXR. The aim of this study was to investigate the hepatoprotective effect of crocin against DXR used in cancer treatment.
H. Elbe, Y. Bicer, Onal, M. O., Bicer, Y., O. Koca, Koca, O., E. Altinoz, M. Demir, Elbe, H., M.O. Onal, Demir, M., Altinoz, E., M. Karayakali, Karayakali, M.   +13 more
core   +2 more sources

Orally Administered Crocin Protects Against Cerebral Ischemia/Reperfusion Injury Through the Metabolic Transformation of Crocetin by Gut Microbiota

Frontiers in Pharmacology, 2019
Our pilot study suggested that orally administered crocin was hardly absorbed into circulatory system, but it was effective against cerebral ischemic/reperfusion (I/R) injury.
Yue Zhang, Jianliang Geng, Yu Hong, Li Jiao, Shuning Li, Runbin Sun, Yuan Xie, Caixia Yan, Jiye Aa, Guangji Wang   +9 more
doaj   +1 more source

Role of Dietary Crocin in In Vivo Melanoma Tumor Remission [PDF]

, 2017
Background: Melanoma is a deadly form of malignancy. Early diagnosis might pave the way to cure but its aggressive nature leads to rapid dissemination and colonization of distant organs. Dietary herbs may play a significant role in prevention of cancer.
Bakshi, Hamid A., Bakshi, Hamid, Sam, Smitha, Javid, Farideh, Hakim, Faruck, Hakkim, Faruck   +5 more
core   +1 more source

Is Crocin a Potential Anti-tumor Candidate Targeting Microtubules? Computational Insights From Molecular Docking and Dynamics Simulations

Frontiers in Molecular Biosciences, 2020
Although it is known crocin, a hydrophilic compound from the herbal plant Crocus sativus L., has promising antitumor activity, the detailed mechanism of its antitumor activity was not well understood.
Ze Wang, Juan Ren, Nengzhi Jin, Xingyi Liu, Xiaofei Li   +4 more
doaj   +1 more source

Advances on the anti-tumor mechanisms of the carotenoid Crocin [PDF]

, 2023
Saffron is located in the upper part of the crocus stigma of iridaceae, which has a long history of medicinal use. Crocin (molecular formula C44H64O24) is a natural floral glycoside ester compound extracted from saffron, which is a type carotenoid ...
Yan Zhao, Hairong Zhang, Xingxun Bao, Lei Xia, Jinhua Hu, Ruixue Jia   +5 more
core   +1 more source

A preliminary study of the anti-inflammatory and anti-apoptotic effects of crocin against gastric ischemia-reperfusion injury in rats

Brazilian Journal of Pharmaceutical Sciences, 2015
The aim of the present study was to investigate the protective effect of crocin on gastric mucosal lesions caused by ischemia-reperfusion (I/R) injury in rats.
Seyyed Ali Mard, Zahra Nikraftar, Yaghoob Farbood, Esrafil Mansouri   +3 more
doaj   +1 more source

Crocin Inhibits Angiogenesis and Metastasis in Colon Cancer via TNF-?/NF-kB/VEGF Pathways.

, 2022
Angiogenesis and metastasis play pivotal roles in the progression of cancer. We recently discovered that crocin, a dietary carotenoid derived from the Himalayan crocus, inhibited the growth of colon cancer cells.
Gerry A Quinn (17249992), Vijay Mishra (4870402), Ángel Serrano-Aroca (4452994), Mohamed El-Tanani (419364), Murtaza Tambuwala (17168338), Hamid A Bakshi (13491235), Mohamed M Nasef (17249887), Alaa A A Aljabali (17249707), Mateus Webba Da Silva (17249995), Paul A McCarron (9694684)   +9 more
core   +4 more sources

Protective role of crocin against sepsis-induced injury in the liver, kidney and lungs via inhibition of p38 MAPK/NF-κB and Bax/Bcl-2 signalling pathways

Pharmaceutical Biology, 2022
Context Crocin has been reported to have multiple bioactivities. However, the effect of crocin administration on caecal ligation and puncture (CLP)-induced sepsis remains unknown.Objective We investigated the effects of crocin on CLP-induced sepsis in ...
Jun Gao, Feng Zhao, Shaona Yi, Shuhang Li, Aiqing Zhu, Yingxiu Tang, Aiqun Li   +6 more
doaj   +1 more source