Results 61 to 70 of about 3,702 (135)

Effects of chronic crocin treatment on desoxycorticosterone acetate (doca)-salt hypertensive rats [PDF]

Iranian Journal of Basic Medical Sciences, 2014
Objective(s): In this study, the effects of chronic administration of crocin, an active constituent of saffron, on blood pressures of normotensive and desoxycorticosterone acetate (DOCA) - salt induced hypertensive rats, were investigated.
Mohsen Imenshahidi, Bibi Marjan Razavi, Ayyoob Faal, Ali Gholampoor, Seyed Mehran Mousavi, Hossein Hosseinzadeh   +5 more
doaj  

Hydrogen bonding network dynamics of crocin–water binary solutions by Raman spectroscopy [PDF]

AIP Advances
Crocin is a natural pigment with diverse physiological activities and finds extensive applications in the pharmaceutical, food, and cosmetics industries.
Minglei Qu, Wenhui Fang, Zhiwei Men
doaj   +1 more source

Antioxidant effect of crocin on scopolamine-induced memory deficits and oxidative stress in experimental animal model [PDF]

Aswan University Journal of Environmental Studies
Alzheimer's disease (AD), a term of neurodegenerative diseases that has characteristic clinical and pathological symptoms. Numerous studies have found that using natural products as expected treatments for neurodegeneration has health-promoting ...
Safinaz El-Baga, Eatemad Awadalla, ‪Mohammed Hassan‬, Abdelkader Abdelkader   +3 more
doaj   +1 more source

Complete microbial synthesis of crocetin and crocins from glycerol in Escherichia coli

Microbial Cell Factories
Background Crocin, a glycosylated apocarotenoid pigment predominantly found in saffron, has garnered significant interest in the field of biotechnology for its bioactive properties.
Jun Ho Lee, Seong-Rae Lee, Sang Yup Lee, Pyung Cheon Lee   +3 more
doaj   +1 more source

Crocin Restores Hypotensive Effect of Subchronic Administration of Diazinon in Rats [PDF]

Iranian Journal of Basic Medical Sciences, 2013
Objective(s): In this study, the effects of crocin against subchronic toxicity of diazinon (DZN) on systolic blood pressure (SBP) and heart rate (HR) were evaluated in rats.
Marjan Razavi, Hossein Hosseinzadeh, Khalil Abnous, Vahideh Sadat Motamedshariaty, Mohsen Imenshahidi   +4 more
doaj  

Crocin promotes ferroptosis in gastric cancer via the Nrf2/GGTLC2 pathway

Frontiers in Pharmacology
Introduction: Gastric cancer (GC) is characterized by high incidence and poor survival rates. Crocin, a natural carotenoid from saffron, exhibits antioxidant, anti-inflammatory, and anti-tumor properties.
Nan Yan, Gaofu Li, Linglin Zhao, Qijing Guo, Jie Yang, Jianhong Liu, Wei Zhou, Yue Gao, Yue Gao, Yushuang Luo, Yushuang Luo   +10 more
doaj   +1 more source

Inhibitory Effect of Crocin(s) on Lens α-Crystallin Glycation and Aggregation, Results in the Decrease of the Risk of Diabetic Cataract

Molecules, 2016
The current study investigates the inhibitory effect of crocin(s), also known as saffron apocarotenoids, on protein glycation and aggregation in diabetic rats, and α-crystallin glycation.
Fereshteh Bahmani, Seyedeh Zahra Bathaie, Seyed Javid Aldavood, Arezou Ghahghaei   +3 more
doaj   +1 more source

Comparative Evaluation of Antidepressant and Anxiolytic Effects of Escitalopram, Crocin, and their Combination in Rats

Advanced Biomedical Research
Background: Chronic stress can lead to anxiety and depression. Escitalopram is a selective serotonin reuptake inhibitor (SSRI), and crocin is a natural compound derived from saffron.
Mehran Joodaki, Maryam Radahmadi, Hojjatallah Alaei   +2 more
doaj   +1 more source

Toxic Effects of Methotrexate on Rat Kidney Recovered by Crocin as a Consequence of Antioxidant Activity and Lipid Peroxidation Prevention

Iranian Biomedical Journal, 2020
Background: The application of methotrexate (MTX) as a chemotherapy agent and immune system suppressant has various side effects. Crocin, a xanthine derivative plant, has many therapeutic benefits. This study was planned to assess the effect of crocin on
Cyrus Jalili, Ali Ghanbari, Shiva Roshankhah, Mohammad Reza Salahshoor   +3 more
doaj  

Integration of Network Pharmacology, Molecular Docking, and Molecular Dynamics to Decipher the Multi-Target Mechanisms of Crocin I in Parkinson's Disease with In Vivo Validation. [PDF]

ACS Omega
Wang J, Lv M, Yu J, Xu Y, Lin Y, Pei J, Zhou M.   +6 more
europepmc   +1 more source