Results 91 to 100 of about 97,874 (310)

Clinical variables related to small bowel obstruction: comparison of patients with and without Crohn’s disease

Gastroenterology Insights, 2012
Small bowel obstruction is a known complication of Crohn’s disease. Determining need for operation is a demanding task. The aim of this study was to fine tune the decision-making process by evaluating standard clinical and laboratory parameters in small ...
Awad Al Qahtani, Christina Holcroft, Philip Gordon, Andrew Szilagyi   +3 more
doaj   +1 more source

MOESM1 of Vitamin D deficiency associated with Crohnâ s disease and ulcerative colitis: a meta-analysis of 55 observational studies

, 2019
Additional file 1: Method S1. Search strategy.
Li, Xi-Xi, Liu, Yang, Luo, Jie, Huang, Zhen-Dong, Zhang, Chao, Fu, Yan   +5 more
openaire   +1 more source

Emerging patterns of genetic overlap across autoimmune disorders. [PDF]

, 2012
Most of the recently identified autoimmunity loci are shared among multiple autoimmune diseases. The pattern of genetic association with autoimmune phenotypes varies, suggesting that certain subgroups of autoimmune diseases are likely to share ...
Criswell, Lindsey A, Richard-Miceli, Corinne   +1 more
core   +1 more source

Zinc Alleviates Gut Barrier Dysfunction by Promoting the Methylation of AKT

Advanced Science, EarlyView.
Zinc activates the ZNG1‐METAP1 complex to elevate intracellular SAM levels, which promotes PRMT5‐mediated symmetrical dimethylation of AKT at R391 and R15. This epigenetic modification facilitates AKT membrane translocation and mTORC2 activation, thereby enhancing epithelial proliferation and gut barrier integrity.
Chuanjiang Cai, Yining Zheng, Bo Sun, Guoyan Wang, Pengfei Li, Huijun Geng, Rongnuo Li, Miaomiao Zhu, Yuanyuan Zhu, Dingping Feng, Lei Chen, Guiyan Chu, Lu Deng, Shiyan Qiao   +13 more
wiley   +1 more source

Additional file 3: Table S2. of Systematic review with meta-analysis: the efficacy and safety of stem cell therapy for Crohnâ s disease

, 2017
Assessment of quality of observational studies using Newcastle Ottawa Quality Assessment Scale (NOS) (DOCX 14Â kb)
Qiu, Yun, Man-Ying Li, Feng, Ting, Feng, Rui, Mao, Ren, Bai-Li Chen, He, Yao, Zeng, Zhi-Rong, Zhang, Sheng-Hong, Min-Hu Chen   +9 more
openaire   +1 more source

Efficacy of adalimumab as second-line therapy in a pediatric cohort of crohn’s disease patients who failed infliximab therapy: The Italian society of pediatric gastroenterology, hepatology, and nutrition experience [PDF]

, 2019
Background: Adalimumab (Ada) treatment is an available option for pediatric Crohn’s disease (CD) and the published experience as rescue therapy is limited.
Accomando S., Aloi M., Alvisi P., Arrigo S., Balzani L., Cucchiara S., De Giacomo C., Gennari M., Guariso G., Knafelz D., Lionetti P., Martelossi S., Miele E., Ravelli A., Romano C., Zuin G.   +15 more
core   +1 more source

Artificial Intelligence‐Driven Proteomics Identifies Plasma Protein Signatures for Diagnosis and Stratification of Behçet's Disease

Advanced Science, EarlyView.
Molecular and functional landscape of BD progression and severity based on in‐depth proteomics. Tree boosting machine learning models with favorable performance in BD diagnosis and stratification. Efficient biomarker panels for BD diagnosis and stratification. .
Linlin Cheng, Mansheng Li, Zhou Bai, Xiaobo Yu, Wenjie Zheng, Yongzhe Li, Yudong Liu   +6 more
wiley   +1 more source

Additional file 3: of Circulating cathelicidin levels correlate with mucosal disease activity in ulcerative colitis, risk of intestinal stricture in Crohnâ s disease, and clinical prognosis in inflammatory bowel disease

, 2017
Figure S3. Data analysis of UC endoscopic activity. Prevalence, sensitivity, specificity, PPV, NPV, and AUC values of ROC curves of LL-37 test alone, CRP test alone, and both in indicating (A) endoscopic remission and (B) severe UC endoscopic activity.
Tran, Diana, Jiani Wang, Ha, Christina, Ho, Wendy, S. Mattai, Oikonomopoulos, Angelos, Weiss, Guy, Lacey, Precious, Cheng, Michelle, Shieh, Christine, Mussatto, Caroline, Ho, Samantha, Hommes, Daniel, Hon Koon   +13 more
openaire   +1 more source

Is the abundance of Faecalibacterium prausnitzii relevant to Crohn's disease? [PDF]

, 2010
Reports that bacteria within the Firmicutes phylum, especially the species Faecalibacterium prausnitzii, are less abundant in Crohn’s disease (CD) patients and supernatants from cultures of this bacterium are anti-inflammatory prompted the investigation ...
Aminov, Benus, Chapman, Claire Dawson, Costello, David B. Ramsden, Duncan, Fite, Hamer, Harvey, Hunter, Jeffrey A. Cole, John O. Hunter, Johnson, King, Lane, Lesley Griffiths, Levine, Loubinoux, Louis, Louis, Macpherson, Mai, Marquet, Pitcher, Rebekah N. Whitehead, Roediger, Rosemary H. Waring, Sartor, Sartor, Schofield, Smith, Sokol, Tazoe, Van Der Waiij, Wenjing Jia, Whelan, Willis, Yin   +38 more
core   +2 more sources

Reoperative pouch surgery for suspected Crohn's‐related complications aided by biologic coverage: Early experience from an inflammatory bowel disease center

Annals of Gastroenterological Surgery, EarlyView.
This paper demonstrates that revisional/redo ileal pouch anal anastomosis (IPAA) surgery with concurrent biologic therapy provides a viable, stoma‐free alternative for patients with Crohn's disease‐like complications, showing a high functioning pouch rate and expanding options for managing pouch failure.
Mehmet Gulmez, Daniel J. Wong, Ariela K. Holmer, Eren Esen, Shannon Chang, Arman Erkan, David Hudesman, Andre da Luz Moreira, Feza H. Remzi   +8 more
wiley   +1 more source