Results 91 to 100 of about 181,689 (337)

Reoperative pouch surgery for suspected Crohn's‐related complications aided by biologic coverage: Early experience from an inflammatory bowel disease center

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This paper demonstrates that revisional/redo ileal pouch anal anastomosis (IPAA) surgery with concurrent biologic therapy provides a viable, stoma‐free alternative for patients with Crohn's disease‐like complications, showing a high functioning pouch rate and expanding options for managing pouch failure.
Mehmet Gulmez   +8 more
wiley   +1 more source

Time series analysis of Parkinson's disease, Huntington's disease and Amyotrophic Lateral Sclerosis [PDF]

open access: yesarXiv, 2013
The aim of this paper is to study the (clinical) time-series data of three diseases with complex dynamics: Parkinson's disease, Huntington's disease and Amyotrophic Lateral Sclerosis. For this purpose, first all of the time series data are embedded in a vector space of suitable dimension and then the correlation dimension of the above mentioned ...
arxiv  

Analysis of the human diseasome reveals phenotype modules across common, genetic, and infectious diseases [PDF]

open access: yes, 2014
Phenotypes are the observable characteristics of an organism arising from its response to the environment. Phenotypes associated with engineered and natural genetic variation are widely recorded using phenotype ontologies in model organisms, as are signs and symptoms of human Mendelian diseases in databases such as OMIM and Orphanet.
arxiv   +1 more source

Environmental toxicity influences disease spread in consumer population [PDF]

open access: yesarXiv, 2022
The study of infectious disease has been of interest to ecologists since long. The initiation of epidemic and the long term disease dynamics are largely influenced by the nature of the underlying consumer (host)-resource dynamics. Ecological traits of such systems may be often modulated by toxins released in the environment due to ongoing anthropogenic
arxiv  

Mechanisms of Intestinal Epithelial Barrier Dysfunction by Adherent-Invasive Escherichia coli. [PDF]

open access: yes, 2016
Pathobiont expansion, such as that of adherent-invasive Escherichia coli (AIEC), is an emerging factor associated with inflammatory bowel disease. The intestinal epithelial barrier is the first line of defense against these pathogens.
McCole, Declan F, Shawki, Ali
core   +1 more source

Clinical and Economic Insights Into Surgery for Colonic Diverticular Perforation: A Long‐Term Observational Cohort Study

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
The sigmoid colon was the most common perforation site among patients with colonic diverticular perforation. The patients' conditions, length of hospital stay, and hospitalization cost were significantly worse in left‐sided colon diverticular perforation than in right‐sided colon diverticular perforation. The clinical characteristics differed according
Minoru Fujita   +29 more
wiley   +1 more source

Activity of species-specific antibiotics against Crohnʼs disease–associated adherent-invasive Escherichia coli [PDF]

open access: yes, 2015
Background: Crohn's disease (CD) is associated with bacterial dysbiosis that frequently includes colonization by adherent-invasive Escherichia coli (AIEC).
Brown, Carla L.   +3 more
core   +1 more source

Prognostic Value of Serum Insulin‐Like Growth Factor‐1 in Patients With Anal Fistula Treated by Incision‐Thread‐Drawing Surgery

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
IGF‐1 levels above 174.9 ng/mL were associated with better wound healing and lower postoperative inflammation. Higher IGF‐1 levels correlated with improved anal function at 7 and 14 days post‐surgery. ABSTRACT Background Anal fistula is a chronic condition characterized by an abnormal tract between the anal canal and perianal skin, often leading to ...
Zhijun Wu, Xuexue Yin, Jing Li
wiley   +1 more source

Increasing the Discovery Power and Confidence Levels of Disease Association Studies: A Survey [PDF]

open access: yesarXiv, 2017
The majority of common diseases are influenced by multiple genetic and environmental factors such as Cancer. Even though uncovering the main causes of disease is deemed difficult due to the complexity of gene-gene and gene-environment interactions, major research efforts aim at identifying disease risk factors, especially genetic ones.
arxiv  

Non-Invasive monitoring of Inflammatory Bowel Disease : time to use newer tools? [PDF]

open access: yes, 2013
Introduction: In inflammatory bowel disease (IBD), commonly used biomarkers employed for non-invasive monitoring of disease activity are the C-reactive Protein (CRP) and Erythrocyte Sedimentation Rate (ESR). Ulcerative colitis (UC) has a modest to absent
Azzopardi, Neville
core  

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