Results 101 to 110 of about 9,364,795 (319)

Granulomatous Cheilitis and Crohn's Disease

Canadian Journal of Gastroenterology, 2001
Granulomatous cheilitis is characterized by recurrent swelling of the labial tissues and granulomatous histology. Granulomatous cheilitis has been recognized as an early manifestation of Crohn's disease.
Ishfaq Ahmad, David Owens
doaj   +1 more source

Uveitis as first manifestation of probably Crohn's disease

Revista Brasileira de Oftalmologia, 2012
Extraintestinal manifestations of Crohn's disease are common. Although ocular complications of Crohn's disease are infrequent, most ocular manifestations include iritis, uveitis, episcleritis, scleritis and conjuntivitis.
Ieda Maria Alexandre Barreira, Ricardo Evangelista Marrocos de Aragão, Ariosto Bezerra Vale, Virgínia Apolônio Vieira, Luanna Biana Costa Bezerra   +4 more
doaj   +1 more source

A CD3-Specific Antibody Reduces Cytokine Production and Alters Phosphoprotein Profiles in Intestinal Tissues From Patients With Inflammatory Bowel Disease [PDF]

, 2014
NOTICE: this is the author’s version of a work that was accepted for publication in Gastroenterology. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms ...
Alegre, Andrew J. Stagg, André van Maurik, Anna Vossenkämper, Baumgart, Belmar, Capasso, Cardone, Chang, Christian Hundsrucker, Di Sabatino, Fedorak, Filipovich, Glocker, Herold, Hirsch, Kevin Page, Keymeulen, Keymeulen, Kotlarz, Lisa Das, Macdonald, Mehta, Monteleone, Monteleone, Monteleone, Pfaffl, Plevy, Prentice, Rovedatti, Sandborn, Schreiber, Theodore J. Sanders, Thomas T. MacDonald, Tran, van der Woude, Van Wauwe, Vossenkämper, Waldron-Lynch, Wiczling, Wu, Wu, Yu   +42 more
core   +1 more source

Dendrobium Officinale‐Derived Carbon Dots Nanozymes Alleviate Colitis by Orchestrating Intestinal Mucus‐Epithelium‐Immune Barriers

Advanced Science, EarlyView.
Dendrobium officinale‐derived carbon dots (DO‐CDs) exhibiting enzyme‐mimetic activities are synthesized via a hydrothermal approach. In the colitis model, DO‐CDs effectively facilitated the repair of mucosal, epithelial, and immune barriers by upregulating the expression of mucins and tight junction proteins, as well as re‐establishing intestinal ...
Chenxi Xu, Xiaoling Huang, Zhichao Deng, Ruiying Wang, Seyedalireza Ghazimirsaeid, Li Yao, Yuanyuan Zhu, Bowen Gao, Junlong Fu, Mingxin Zhang, Mei Yang, Mingzhen Zhang   +11 more
wiley   +1 more source

Non-invasive fluorescence sensing reveals changes in intestinal barrier function and gastric emptying rate in a first-in-human study of Crohn’s disease

Therapeutic Advances in Gastroenterology
Background: Crohn’s disease is characterised by multifaceted changes in gut function, involving not just inflammatory effects but also alterations in gut barrier function and gastric motility.
Jonathan Gan, Qian Chen, Elena Monfort Sanchez, Nilanjan Mandal, Jiacheng Xu, Zixin Wang, Arjun Agarwal, Emmanuel Oluwatunmise, Pratik Ramkumar, Ash Salam, Elena Chekmeneva, María Gómez-Romero, Lynn Maslen, Sharmili Balarajah, Robert Perry, Karl King Yong, Jonathan Hoare, Nick Powell, James Alexander, James Avery, Hutan Ashrafian, Ara Darzi, Alex J. Thompson   +22 more
doaj   +1 more source

Impact of fatigue in Crohn's disease is negatively related to resting state functional connectivity between the superior parietal lobule and parahippocampal gyrus/hippocampus

Frontiers in Human Neuroscience
IntroductionCrohn's disease is one phenotype of inflammatory bowel disease (IBD). Fatigue is a common and burdensome symptom for persons with Crohn's disease.
Theresa A. McIver, Theresa A. McIver, Theresa A. McIver, Charles N. Bernstein, Charles N. Bernstein, Ruth Ann Marrie, Ruth Ann Marrie, Chase R. Figley, Chase R. Figley, Md Nasir Uddin, Md Nasir Uddin, Md Nasir Uddin, John D. Fisk, Lesley A. Graff, Lesley A. Graff, Ronak Patel, Erin L. Mazerolle, Jennifer Kornelsen, Jennifer Kornelsen, Jennifer Kornelsen   +19 more
doaj   +1 more source

Anticipation in an Indo-Canadian Family with Crohn's Disease

Canadian Journal of Gastroenterology, 2001
Genetic anticipation, associated elsewhere with monogenic neurological disorders, has been hypothesized to be present in familial forms of Crohn's disease. Usually, with studies of parent-child pairs, the parent who is initially diagnosed is older at the
Hugh J Freeman, Noel B Hershfield
doaj   +1 more source

Intestinal Neutral Ceramidase Deficiency Triggers Regulatory T Cell Response via Gd3 to Protect the Host from Intestinal Inflammation

Advanced Science, EarlyView.
Deletion of ASAH2 in intestinal epithelial cells induces the accumulation of ganglioside GD3 via regulating ST8SIA1. GD3 is identified as the glycolipid ligand for the inhibitory receptor Siglec‐E on macrophages. GD3/Siglec‐E ligation polarizes macrophages and promotes the proliferation of colonic ST2+ T regulatory cells via the induction of IL‐33. The
Zhishan Xu, Chao Lei, Mukesh K Sriwastva, Ting Wang, Amanguli Tuohongerbieke, Xiaotong Song, Collin Noud, Shannon Derkson, Yi Tan, Gerald Dryden, Craig J McClain, Zhongbin Deng   +11 more
wiley   +1 more source

Improvement with Infliximab of a Disseminated Sarcoidosis in a Patient with Crohn’s Disease

Case Reports in Pulmonology, 2014
Sarcoidosis and Crohn’s disease are systemic granulomatous disorders affecting the lung and the intestine, respectively, with variable involvement of other organs and are seldom associated.
Nader Chebib, Fabrice Piégay, Julie Traclet, François Mion, Jean-François Mornex   +4 more
doaj   +1 more source

A microbial signature for Crohn's disease

Gut, 2017
Objective A decade of microbiome studies has linked IBD to an alteration in the gut microbial community of genetically predisposed subjects. However, existing profiles of gut microbiome dysbiosis in adult IBD patients are inconsistent among published ...
V. Pascal, M. Pozuelo, N. Borruel, F. Casellas, D. Campos, A. Santiago, Xavier Martinez, E. Varela, G. Sarrabayrouse, K. Machiels, S. Vermeire, H. Sokol, F. Guarner, C. Manichanh   +13 more
semanticscholar   +1 more source