Results 111 to 120 of about 9,364,795 (319)

Bone Marrow Mesenchymal Stem Cell Hydrogel‐Mediated Fibroblast Reprogramming Restores Intestinal Function in Adhesive Small Bowel Obstruction

Advanced Science, EarlyView.
Conceptual diagram and schematic illustration of microenvironmental changes in individuals with ASBO before and after treatment. BMSC@Gel therapy transforms the ASBO microenvironment from an inflammatory, fibrotic state with aberrant matrix deposition and barrier dysfunction to a regenerative state with reduced inflammation and improved structural ...
Lihong Zheng *, Junrong Zhang *, Zhengyuan Huang *, Zhenliang Lin, Jin Zhang, Da Zhang, Ping Hou, Xianqiang Chen   +7 more
wiley   +1 more source

A Rare Manifestation of Crohn's Disease: Sinonasal Granulomatosis. Report of a Case and Review of Literature

European Journal of Case Reports in Internal Medicine, 2014
Crohn’s disease is a granulomatous inflammatory bowel disease. Its pathologic findings include non-contiguous chronic inflammation and non-caseating granulomas, sometimes with extra-intestinal localizations.
Lilia Baili, Imène Rachdi, Fatma Daoud, Zohra Aydi, Basma Ben Dhaou, Samir Kochbati, Fatma Boussema   +6 more
doaj   +1 more source

Macrophage‐Targeted Magnesium Ion‐Nourisher for NLRP3 Inflammasome Inhibition to Enhance Liver Inflammatory Disease Treatment

Advanced Science, EarlyView.
This report describes a nano magnesium nourisher, named MgC@PS, capable of targeted Mg2⁺ delivery to macrophages, effectively suppressing The nuclear factor kappa B (NF‐κB) activation and mitigating NLRP3 inflammasome‐driven pyroptosis in liver inflammation.
Li Wang, Zhuo Yan, Sindhu Yalavarthi, Yusif Abdul‐Rashid, Kiki Parker, Kyle Nowlin, Ethan Li, Jordan Mack, Josephine Wei, Hunter Vu, Zhenquan Jia, Jianjun Wei, Jilong Wang, Kerui Wu   +13 more
wiley   +1 more source

Crohn’s Disease: a Role of Gut Microbiota and Nod2 Gene Polymorphisms in Disease Pathogenesis

Acta Medica, 2014
Crohn’s disease is a chronic immune-mediated intestinal inflammation targeted against a yet incompletely defined subset of commensal gut microbiota and occurs on the background of a genetic predisposition under the influence of environmental factors ...
Lucia Hrnčířová, Jan Krejsek, Igor Šplíchal, Tomáš Hrnčíř   +3 more
doaj   +1 more source

Switching from reference infliximab to CT-P13 in patients with inflammatory bowel disease: 12 months results [PDF]

, 2017
Background: Biological agents, such as infliximab, have transformed the outcomes of patients with immune-mediated inflammatory diseases. The advent of biosimilar treatment options such as CT-P13 promises to improve the availability of biological therapy,
Argüelles Arias, Federico, Castro Laria, Luisa, Guerra Veloz, María Fernanda, Maldonado Pérez, Belén, Merino Bohórquez, Vicente, Perea Amarillo, Raúl, Romero Gómez, Manuel, Vilches Arenas, Ángel   +7 more
core  

Extended haplotype association study in Crohn’s disease identifies a novel, Ashkenazi Jewish-specific missense mutation in the NF-κB pathway gene, HEATR3 [PDF]

, 2014
The Ashkenazi Jewish population has a several-fold higher prevalence of Crohn’s disease compared to non-Jewish European ancestry populations and has a unique genetic history.
Abraham, Clara, Brant, Steven R., Burberry, Aaron, Cardinale, Christopher J., Cho, Judy H., Choi, Murim, Chowers, Yehuda, Desnick, Robert J., Evelyn Ng, Sok Meng, Ferguson, John, Gregersen, Peter K., Gusev, Alexander, Hakonarson, Hakon, Hui, Ken Y., Karban, Amir, Katz, Seymour, Lifton, Richard P., Mayer, Lloyd, Nuñez, Gabriel, Peter, Inga, Pe’er, Itsik, Silverberg, Mark S., Warner, Neil, Waterman, Matti, Zhang, Wei, Zhao, Hongyu   +25 more
core   +1 more source

Gastrointestinal Histoplasmosis Mimicking Crohn’s Disease [PDF]

, 2021
Esfandiar Shojaei, Joanna C. Walsh, Nikhil Sangle, Brian Yan, Michael Silverman, Seyed M. Hosseini‐Moghaddam   +5 more
openalex   +1 more source

Nanozymes for Non‐Neoplastic Diseases: Catalytic Therapy Redefined

Aggregate, EarlyView.
Non‐neoplastic diseases pose a significant health burden. Nanozymes, enzyme‐like nanomaterials, offer promising strategies for regulating oxidative stress and inflammation. This review explores their development, structure–function relationships, and therapeutic potential, with a focus on precision medicine through targeted delivery and multimodal ...
Ling Mei, Xikai Wang, Zhuang Hu, Jierui Yan, Xiaobo Wang, Haoran Wang, Ya Hou, Pengfei Zhang, Qihang Ding   +8 more
wiley   +1 more source

A case of chronic recurrent multifocal osteomyelitis associated with Crohn's disease [PDF]

, 2015
Chronic recurrent multifocal osteomyelitis (CRMO) is an auto-inflammatory bone disease of unknown etiology, most commonly affecting the metaphysis of long bones, especially the tibia, femur and clavicle. The clinical spectrum varies from self-limited uni-
De Baets, Frans, Dehoorne, Jo, Van Biervliet, Stephanie, van Ommen, Christi, Van Winckel, Myriam, Vande Velde, Saskia   +5 more
core  

Screw‐Based Pill for Intelligent Robotic Extraction of Viscous Fluids in Medical Applications

Advanced Intelligent Systems, EarlyView.
Screw‐based pill for intelligent robotic extraction (S‐PIRE) is a magnetically actuated smart capsule with a motorized screw, 3‐axis sensor, and Bluetooth control for site‐specific and minimally invasive remote sampling of viscous fluids, overcoming passive diffusion limitations.
Prima Dewi Sinawang, Victor Garcia‐Gradilla, Fernando Soto, Demir Akin, Margaret Braunreuther, Gerald G. Fuller, Utkan Demirci   +6 more
wiley   +1 more source