Results 81 to 90 of about 9,364,795 (319)

Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5.

Journal of Immunology, 1996
In this study, we investigate whether human inflammatory bowel disease (IBD) (ulcerative colitis and Crohn's disease) is associated with altered lymphokine secretion profiles, as recently found in various animal models of chronic intestinal inflammation.
I. Fuss, M. Neurath, M. Neurath, M. Boirivant, J. Klein, C. Motte, S. Strong, C. Fiocchi, C. Fiocchi, W. Strober   +9 more
semanticscholar   +1 more source

Dynamic Profiling of Lipoteichoic Acid (LTA) and/or Lipopolysaccharide (LPS) Positive Extracellular Vesicles in Plasma as Diagnostic and Prognostic Biomarkers for Bacterial Infection

Advanced Science, EarlyView.
Using nano‐flow cytometry, this study analyzes the dynamic characteristics of lipoteichoic acid (LTA) and/or lipopolysaccharide (LPS) positive extracellular vesicles in the bloodstream of patients with bacterial infections, providing promising biomarkers for rapid and accurate diagnosis.
Qianqian Gao, Wenwu Zhou, Nadira Nurxat, Ke Xu, Yunyun Xu, Wei Li, Tianchi Chen, Cong Hu, Liang Dong, Qian Liu, Min Li   +10 more
wiley   +1 more source

Adalimumab - an effective and promising treatment for patients with fistulizing Crohn's disease: a case series

Journal of Medical Case Reports, 2011
Introduction Crohn's disease is a chronic inflammatory bowel disease of unknown etiology which may affect any part of the bowel. Fistulas are a common and often serious complication of Crohn's disease. The treatment for fistulizing Crohn's disease can be
Simopoulos Konstantinos, Gatopoulou Anthia, Souftas Vassilios D, Liratzopoulos Nikolaos, Zezos Peter, Efremidou Eleni I, Kouklakis George, Manolas Konstantinos J   +7 more
doaj   +1 more source

Affect and Metaphor Sensing in Virtual Drama [PDF]

, 2010
We report our developments on metaphor and affect sensing for several metaphorical language phenomena including affects as external entities metaphor, food metaphor, animal metaphor, size metaphor, and anger metaphor.
Barnden, John, Zhang, Li
core   +3 more sources

Inclusion of the Mesentery in Ileocolic Resection for Crohn’s Disease is Associated With Reduced Surgical Recurrence

Journal of Crohn's & Colitis, 2018
Background and Aims Inclusion of the mesentery during resection for colorectal cancer is associated with improved outcomes but has yet to be evaluated in Crohn’s disease.
C. Coffey, M. Kiernan, S. Sahebally, A. Jarrar, J. Burke, P. Kiely, B. Shen, D. Waldron, C. Peirce, M. Moloney, M. Skelly, P. Tibbitts, H. Hidayat, P. Faul, V. Healy, P. O'leary, L. Walsh, P. Dockery, R. O'Connell, Sean T. Martin, F. Shanahan, C. Fiocchi, C. Dunne   +22 more
semanticscholar   +1 more source

Diagnosis, Prognosis, and Drug Target Discovery for Chronic Widespread Pain: A Large Proteogenomic Study

Advanced Science, EarlyView.
Plasma proteomics is leveraged to decode the biological underpinnings of chronic widespread pain. A nested machine learning framework integrates proteomic signatures, prospective outcomes, and Mendelian randomization to uncover 18 causal proteins.
Li Chen, Eoin Kelleher, Ruogu Meng, Duanke Liu, Yuchen Guo, Yunhe Wang, Yaqing Gao, Zhe Huang, Zhu Liang, Shuai Yuan, Chao Zeng, Jun Ma, Yanhui Dong, Anushka Irani, Guanghua Lei, Junqing Xie, Daniel Prieto‐Alhambra   +16 more
wiley   +1 more source

A shared mucosal gut microbiota signature in primary sclerosing cholangitis before and after liver transplantation

Hepatology, EarlyView., 2022
In this study of the gut mucosal microbiota in primary sclerosing cholangitis (PSC), we found consistent microbiota features associated with PSC and recurrent PSC, PSC with inflammatory bowel disease and a persistent gut dysbiosis after liver transplantation Abstract Background and Aims Several characteristic features of the fecal microbiota have been ...
Mikal Jacob Hole, Kristin Kaasen Jørgensen, Kristian Holm, Peder R. Braadland, Malin Holm Meyer‐Myklestad, Asle Wilhelm Medhus, Dag Henrik Reikvam, Alexandra Götz, Krzysztof Grzyb, Kirsten Muri Boberg, Tom Hemming Karlsen, Martin Kummen, Johannes R. Hov   +12 more
wiley   +1 more source

Relevance of monitoring transmural disease activity in patients with Crohn’s disease: current status and future perspectives [PDF]

, 2021
Rune Wilkens, Kerri L. Novak, Christian Maaser, Remo Panaccione, Torsten Kucharzik   +4 more
openalex   +1 more source

Pathophysiology of Crohn’s disease inflammation and recurrence

Biology Direct, 2020
Chron’s Disease is a chronic inflammatory intestinal disease, first described at the beginning of the last century. The disease is characterized by the alternation of periods of flares and remissions influenced by a complex pathogenesis in which ...
L. Petagna, A. Antonelli, C. Ganini, V. Bellato, M. Campanelli, A. Divizia, C. Efrati, M. Franceschilli, A. Guida, S. Ingallinella, F. Montagnese, B. Sensi, L. Siragusa, Giuseppe S. Sica   +13 more
semanticscholar   +1 more source

Polydopamine Nanodots Ameliorate Inflammatory Bowel Disease by Restoring Redox Homeostasis and Intestinal Microenvironment

Advanced Science, EarlyView.
A novel melanin‐based therapeutic composed of ultrasmall polydopamine nanodots is employed as an efficient oral formulation for the targeted treatment of inflammatory bowel disease. The potential therapeutic mechanism of polydopamine nanodots mainly involves the elimination of excessive oxidative stress, the reduction of ROS‐mediated proinflammatory ...
Zhen Ding, Xingfu Bao, Ying Zhao, Lin Bai, Jinming Zhang, Chengjing Xu, Tianyan Chen, Shuang Dai, Yufu Liu, Min Hu, Meng Qin, Zhen Liu   +11 more
wiley   +1 more source