Results 51 to 60 of about 62,187 (355)

Diagnosis, Prognosis, and Drug Target Discovery for Chronic Widespread Pain: A Large Proteogenomic Study

Advanced Science, EarlyView.
Plasma proteomics is leveraged to decode the biological underpinnings of chronic widespread pain. A nested machine learning framework integrates proteomic signatures, prospective outcomes, and Mendelian randomization to uncover 18 causal proteins.
Li Chen, Eoin Kelleher, Ruogu Meng, Duanke Liu, Yuchen Guo, Yunhe Wang, Yaqing Gao, Zhe Huang, Zhu Liang, Shuai Yuan, Chao Zeng, Jun Ma, Yanhui Dong, Anushka Irani, Guanghua Lei, Junqing Xie, Daniel Prieto‐Alhambra   +16 more
wiley   +1 more source

Oropharyngeal Crohn’s disease

Clinical and Experimental Gastroenterology, 2008
Rachid Mohamed, Robert Schultz, Richard N FedorakDivision of Gastroenterology, University of Alberta, Edmonton, AlbertaAbstract: Crohn’s disease is a chronic inflammatory disease that can affect any part of the gastrointestinal tract ...
Rachid Mohamed, Robert Schultz, Richard N Fedorak   +2 more
doaj  

Computed tomography enterography and magnetic resonance enterography in small intestine of Crohn's disease

Journal of Coloproctology, 2017
Crohn disease is defined as a chronic inflammatory and idiopathic process that can affect any portion of the gastrointestinal tract. The small intestine is the most frequently affected place, so small bowel morphology investigation is often mandatory.For
Aida Cristina Correia Oliveira Azevedo, Sandra Fátima Fernandes Martins   +1 more
doaj   +1 more source

Inflammatory Bowel Disease-Experience of a pediatric gastroenterology unit [PDF]

, 2013
Inflammatory bowel disease, especially Crohn disease, had increased in the last five decades. We analyzed all the patients of our unit diagnosed with the disease between 2001-2012 but we just considered the patients who respected the Porto criteria to ...
Antunes, Henedina, Nascimento, João
core   +1 more source

Polydopamine Nanodots Ameliorate Inflammatory Bowel Disease by Restoring Redox Homeostasis and Intestinal Microenvironment

Advanced Science, EarlyView.
A novel melanin‐based therapeutic composed of ultrasmall polydopamine nanodots is employed as an efficient oral formulation for the targeted treatment of inflammatory bowel disease. The potential therapeutic mechanism of polydopamine nanodots mainly involves the elimination of excessive oxidative stress, the reduction of ROS‐mediated proinflammatory ...
Zhen Ding, Xingfu Bao, Ying Zhao, Lin Bai, Jinming Zhang, Chengjing Xu, Tianyan Chen, Shuang Dai, Yufu Liu, Min Hu, Meng Qin, Zhen Liu   +11 more
wiley   +1 more source

Mild Clinical Behaviour of Crohn Disease in Elderly Patients in a Latin American Country: A Case-Control Study

Canadian Journal of Gastroenterology and Hepatology, 2015
BACKGROUND: Crohn disease is characterized by fluctuating clinical behaviour, which is influenced by various factors. There are no data from Latin America that evaluate the clinical behaviour of Crohn disease in elderly patients.
Jesús K Yamamoto-Furusho, Andrea Sarmiento-Aguilar   +1 more
doaj   +1 more source

The human gastrointestinal microbiota and prostate cancer development and treatment [PDF]

, 2020
The human gastrointestinal microbiome contains commensal bacteria and other microbiota that have been gaining increasing attention in the context of cancer development and response to treatment.
Alanee, Alexander, Althuis, Amirian, Arthur, Bostwick, Boursi, Buti, Cheng, Cimadamore, Cockburn, Costello, Cuevas-Ramos, Daniels, De Marzo, De Marzo, Dennis, Dominguez-Bello, Eckburg, Elkahwaji, Elkrief, Figueiredo, Gill, Golombos, Goodman, Graessler, Haller, Hamada, Hatakeyama, Hunter, Iida, Kamps, Lampe, Lara-Tejero, Lenoir, Liss, Masood, Meldrum, Miquel, Miyake, Montassier, Mosca, Mouraviev, Musso, Nakai, O'Hara, Olsson, Paulos, Plottel, Porter, Poutahidis, Punnen, Qin, Redman, Ridlon, Roberts, Roy, Russell, Sfanos, Siegel, Smith, Sokol, Sokol, Sonn, The Global Cancer Observatory, Tulstrup, Vande Voorde, Viaud, Vivarelli, Vétizou, Wilson   +70 more
core   +1 more source

Real-world utilization of top-down and step-up therapy and initial costs in Crohn disease [PDF]

, 2022
Kanya Shah, Aisling R. Caffrey, Andy Szczotka, Dea Belazi, Stephen Kogut   +4 more
openalex   +1 more source

Telocytes in Crohn's disease [PDF]

Journal of Cellular and Molecular Medicine, 2013
AbstractCrohn's disease (CD) is a relapsing chronic inflammatory disorder that may involve all the gastrointestinal tract with a prevalence of terminal ileum. Intestinal lesions have a characteristic discontinuous and segmental distribution and may affect all layers of the gut wall.
A. F. Milia, RUFFO, MARTINA, MANETTI, MIRKO, ROSA, IRENE, D. Conte, FAZI, MARILENA, MESSERINI, LUCA, IBBA, LIDIA   +7 more
openaire   +3 more sources

Intrinsic MicroRNA‐10a Restricts Regulatory T Cell Suppressive Function and Intestinal Repair by Coordinating Transcriptional, Metabolic, and Epithelial Repair Pathways

Advanced Science, EarlyView.
This study identifies microRNA‐10a (miR‐10a) as a key brake on regulatory T cell (Treg) suppressive function and intestinal repair. By targeting Blimp‐1, Uqcrq, and amphiregulin, miR‐10a restrains transcriptional, metabolic, and epithelial programs essential for Treg activity.
Wenjing Yang, Tianming Yu, Hui Yang, Suxia Yao, Ruihua Ma, Elizabeth M Steinert, Karen M Ridge, Weiguo Cui, Navdeep S Chandel, Yingzi Cong   +9 more
wiley   +1 more source