Results 51 to 60 of about 9,352,293 (347)

Oropharyngeal Crohn’s disease

open access: yesClinical and Experimental Gastroenterology, 2008
Rachid Mohamed, Robert Schultz, Richard N FedorakDivision of Gastroenterology, University of Alberta, Edmonton, AlbertaAbstract: Crohn’s disease is a chronic inflammatory disease that can affect any part of the gastrointestinal tract ...
Rachid Mohamed   +2 more
doaj  

Computed tomography enterography and magnetic resonance enterography in small intestine of Crohn's disease

open access: yesJournal of Coloproctology, 2017
Crohn disease is defined as a chronic inflammatory and idiopathic process that can affect any portion of the gastrointestinal tract. The small intestine is the most frequently affected place, so small bowel morphology investigation is often mandatory.For
Aida Cristina Correia Oliveira Azevedo   +1 more
doaj   +1 more source

Fermented Lacticaseibacillus Paracasei Cultures Ameliorate Colitis by Modulating Microbiota‐Derived Tryptophan Metabolism and Macrophage Polarization

open access: yesAdvanced Science, EarlyView.
A solid‐state fermented probiotic (PYW) is developed using wheat bran as substrate, containing high viable Lacticaseibacillus paracasei and bioactive metabolites. PYW alleviates intestinal inflammation by gut microbiota composition, enriching indole derivatives, activating aryl hydrocarbon receptor signaling, and regulating macrophage polarization. PYW
Heng Zhang   +11 more
wiley   +1 more source

Mild Clinical Behaviour of Crohn Disease in Elderly Patients in a Latin American Country: A Case-Control Study

open access: yesCanadian Journal of Gastroenterology and Hepatology, 2015
BACKGROUND: Crohn disease is characterized by fluctuating clinical behaviour, which is influenced by various factors. There are no data from Latin America that evaluate the clinical behaviour of Crohn disease in elderly patients.
Jesús K Yamamoto-Furusho   +1 more
doaj   +1 more source

Tobacco Smoke Exposure From Prenatal To Adolescent Periods Drives IBD Pathogenesis: Dynamic DNA Methylation Signatures Across Lifespan Stages

open access: yesAdvanced Science, EarlyView.
This study illustrates that maternal smoking during pregnancy (MSDP) is an independent risk factor for IBD in offspring, and DNA methylation serves as a key mechanistic pathway connecting early‐life smoking exposure with IBD risk in offspring. That highlights the urgent need for preventive interventions targeting prospective parents and minors to ...
Han Zhang   +11 more
wiley   +1 more source

Metastatic Crohn′s disease

open access: yesIndian Journal of Medical Research, 2015
A 51 year old man presented to the department of Dermatology, Regional University Hospital of Málaga, Málaga, Spain, in May 2013, with remarkable lesions on the perineal, perianal and gluteal regions reaching the top of the lower limbs, which he had first noted two years earlier.
Pérez-Belmonte, Luis-Miguel   +1 more
openaire   +3 more sources

Perianal Crohn's Disease [PDF]

open access: yesClinics in Colon and Rectal Surgery, 2007
Crohn's disease is commonly complicated by perianal manifestations. The surgeon plays a pivotal role in caring for these patients; a detailed history along with a thorough clinical exam provides the treating physician with invaluable information upon which to base further investigations and management decisions.
Bashar, Safar, Dana, Sands
openaire   +2 more sources

Phocaeicola coprophilus‐Derived 6‐Methyluracil Attenuates Radiation‐Induced Intestinal Fibrosis by Suppressing the IDO1‐Kynurenine‐AHR Axis

open access: yesAdvanced Science, EarlyView.
IR‐induced dysbiosis depletes P. coprophilus and its metabolite 6‐methyluracil, leading to disinhibition of the IDO1‐Kyn‐AHR axis. This results in sustained fibroblast activation and collagen deposition, driving radiation induced intestinal fibrosis. ABSTRACT Therapeutic options for radiation‐induced intestinal fibrosis (RIF) remain limited. This study
Jiaxin Zhang   +11 more
wiley   +1 more source

The impact of exclusive enteral nutrition on the intestinal microbiota in inflammatory bowel disease

open access: yesAIMS Microbiology, 2018
It is increasingly clear that the intestinal microbiota plays key roles in the pathogenesis of the conditions known as Crohn disease and ulcerative colitis (jointly known as the inflammatory bowel diseases).
Andrew S Day
doaj   +1 more source

Fistulizing Crohn's Disease

open access: yesClinical and Translational Gastroenterology, 2017
Fistulas still represent one of the most important complications in patients with Crohn's disease (CD). At least one third of CD patients suffer from fistulas during their disease course and amongst them longstanding remission of complex fistulas occurs only in about one third. So far, fistula pathogenesis is only partially understood.
Scharl, Michael   +2 more
openaire   +3 more sources

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