Results 41 to 50 of about 4,084 (213)

Drug and dye binding induced folding of the intrinsically disordered antimicrobial peptide CM15 [PDF]

, 2017
The rapid increase of antimicrobial resistance against conventional antibiotics has resulted in a significant focus on the use of peptides as antimicrobial agents.
Beke-Somfai, Tamás, Bősze, Szilvia, Horváti, Kata, Szigyártó, Imola, Zsila, Ferenc   +4 more
core   +1 more source

Mast Cell Deficiency Protects Mice from Surgery-Induced Neuroinflammation

Mediators of Inflammation, 2020
Neuroinflammation plays a key role in the occurrence and development of neurodegenerative diseases. Microglia, the resident immune cells in the brain, have been recognized to contribute to neuroinflammation.
Xiang Zhang, Hongquan Dong, Fei Wang, Jun Zhang   +3 more
doaj   +1 more source

G protein-coupled receptor 35: an emerging target in inflammatory and cardiovascular disease [PDF]

, 2015
G protein-coupled receptor 35 (GPR35) is an orphan receptor, discovered in 1998, that has garnered interest as a potential therapeutic target through its association with a range of diseases.
Amanda E Mackenzie, Graeme eMilligan, Nina eDivorty, Nina eDivorty, Stuart A. Nicklin   +4 more
core   +3 more sources

Distinct mast cell subpopulations within and around lymphatic vessels regulate lymph flow and progression of inflammatory-erosive arthritis in TNF-transgenic mice

Frontiers in Immunology, 2023
ObjectiveInflammatory-erosive arthritis is exacerbated by dysfunction of joint-draining popliteal lymphatic vessels (PLVs). Synovial mast cells are known to be pro-inflammatory in rheumatoid arthritis (RA).
Yue Peng, Yue Peng, H. Mark Kenney, H. Mark Kenney, Karen L. de Mesy Bentley, Karen L. de Mesy Bentley, Lianping Xing, Lianping Xing, Christopher T. Ritchlin, Christopher T. Ritchlin, Edward M. Schwarz, Edward M. Schwarz   +11 more
doaj   +1 more source

Mast cell targeting hampers prostate adenocarcinoma development but promotes the occurrence of highly malignant neuroendocrine cancers [PDF]

, 2011
Mast cells (MC) are c-Kit-expressing cells, best known for their primary involvement in allergic reactions, but recently reappraised as important players in either cancer promotion or inhibition.
Colombo, M., Mauri, G., Parenza, M., Piconese, S., Pittoni, P., Rigoni, A., Sangaletti, S., TRIPODO, Claudio   +7 more
core   +1 more source

The efficacy of adding oral sodium cromoglycate to stable treatment for controlling bullous pemphigoid-related pruritus: A retrospective study

Frontiers in Medicine, 2022
IntroductionBullous pemphigoid (BP) is the most common autoimmune subepidermal blistering disease which mainly affects the elderly. It manifests as severe pruritus, urticarial plaques, and tense bullae and is associated with significant mortality ...
Noy Keller Rosenthal, Darby Boucher, Dedee F. Murrell, Dedee F. Murrell   +3 more
doaj   +1 more source

Diffuse cutaneous mastocytosis with novel somatic KIT mutation K509I and association with tuberous sclerosis. [PDF]

, 2018
Diffuse cutaneous mastocytosis (DCM) is a rare but potentially fatal condition when diagnosis and targeted treatments are delayed. This case illustrates the life-threatening complications in DCM and reviews the currently available treatments.
Akin, Alvarez-Twose, Bankova, Bodemer, Brockow, Brockow, Caughey, Chan, Edwards, Escribano, Escribano, Flageul, Fried, Galli, Garg, Hannaford, Hartmann, Has, Heide, Huang, Lange, Melo, Murphy, Orkin, Polk, Poterack, Prieto-García, Smith, Tolar, Valent, Wolff, Zhang, Álvarez-Twose   +32 more
core   +1 more source

A double-masked study to compare the efficacy and safety of topical cromolyn for the treatment of allergic conjunctivitis

Journal of the Formosan Medical Association, 2011
To compare the efficacy and safety of topical cromolyn between with and without preservative for the treatment of allergic conjunctivitis. Methods: A double-masked study was performed in patients with allergic conjunctivitis.
Yao-lin Liu, Fung-Rong Hu, I-Jong Wang, Wei-Li Chen, Yu-Chih Hou   +4 more
doaj   +1 more source

Mast cell activation in the acupoint is important for the electroacupuncture effect against pituitrin-induced bradycardia in rabbits

Scientific Reports, 2017
This research was conducted to verify the structural and functional characteristics of mast cells in the electroacupuncture (EA) effects on bradycardia. First, we examined the mast cell density at PC 6, adjacent acupoint LU 7, and a non-acupoint.
Haining Zhu, Xuezhi Wang, Meng Huang, Yi Jing, Di Zhang, Guanghong Ding   +5 more
doaj   +1 more source

Protective Effects of Albuterol, Epinephrine and Cromolyn Against Ovalbumine-Induced Immunotoxicity in the Rat Lungs [PDF]

Journal of Advanced Biomedical Sciences, 2020
Background & Objective: Asthma is a condition in which the respiratory tract is tight and swollen and is associated with increased levels of mucus and inflammatory cells in the airways.
Raham Armand, Mohhamad kazem koohi, Goodarz Sadeghi Hashtchin, Vahhab Babapour, Nasim khankhajeh   +4 more
doaj