Results 161 to 170 of about 526,765 (304)

Molecular Characteristics, Functional Definitions, and Regulatory Mechanisms for Cross-Presentation Mediated by the Major Histocompatibility Complex: A Comprehensive Review. [PDF]

Int J Mol Sci, 2023
Liu S, Wei S, Sun Y, Xu G, Zhang S, Li J.   +5 more
europepmc   +1 more source

Combined killing of cancer cells and cross presentation of tumor antigen by Vγ9Vδ2 T cells [PDF]

, 2015

core   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Proteomic Analysis of Regulated Dendritic Cell Endosomes Reveals Dynamic Adaptation to Antigen Uptake and Cross-Presentation. [PDF]

Eur J Immunol
Senni A, Grumbach L, Ceccacci S, Frechin M, Goudin N, Guerrera IC, Bertocci B, van Endert P.   +7 more
europepmc   +1 more source

Enhancement of Immune Responses Elicited by Nanovaccines through a Cross-Presentation Pathway. [PDF]

Tissue Eng Regen Med, 2023
Kim CG, Lee JC, Ju DB, Kim SK, Yun CH, Cho CS.   +5 more
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

WDFY4-dependent cross-presentation proceeds via a vacuolar antigen-processing route. [PDF]

Proc Natl Acad Sci U S A
Postoak JL, Koch A, Shan S, Ohara RA, Jo S, Chen J, Desai P, Ou F, Kraft M, Diamond MS, Kim S, Murphy TL, Murphy KM.   +12 more
europepmc   +1 more source

Recent progress in type 1 classical dendritic cell cross-presentation - cytosolic, vacuolar, or both? [PDF]

Curr Opin Immunol, 2023
Ohara RA, Murphy KM.
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Cross-presentation of dead cell-associated antigens shapes the neoantigenic landscape of tumor immunity. [PDF]

Nat Immunol
Lim KHJ, Schulz O, Lobon I, Castro-Dopico T, Zapata L, Giampazolias E, Frederico B, Castellanos CA, Buck MD, Stainier W, Chakravarty P, Kelly G, Rogers NC, Cardoso A, Lee S, Vash B, Maiocco S, Mehta R, Strid J, Turajlić S, Reis E Sousa C.   +20 more
europepmc   +1 more source