Results 71 to 80 of about 4,566,251 (289)
(2S,3S)-3-Hydroxyleucine can be found in an increasing number of bioactive natural products. Within the context of our work regarding the total synthesis of muraymycin nucleoside antibiotics, we have developed a synthetic approach towards (2S,3S)-3 ...
Oliver Ries +4 more
doaj +1 more source
Concise Synthesis of Broussonone A
A concise and expeditious approach to the total synthesis of broussonone A, a p-quinol natural compound, has been developed. The key features of the synthesis include the Grubbs II catalyst mediated cross metathesis of two aromatic subunits, and a ...
Hyeju Jo +11 more
doaj +1 more source
Substituted Pyrroles via Olefin Cross-Metathesis
Olefin cross-metathesis (CM) provides a short and convenient entry to diverse trans-γ-aminoenones. When exposed to either acid or Heck arylation conditions, these intermediates are converted to mono-, di-, or trisubstituted pyrroles. The value of this chemistry is demonstrated by its application to the tetrasubstituted pyrrole subunit of Atorvastatin.
Donohoe, TJ +3 more
openaire +3 more sources
An alternate synthetic route to the important anticancer drug suberoylanilide hydroxamic acid (SAHA) from its α,ß-didehydro derivative is described. The didehydro derivative is obtained through a cross metathesis reaction between a suitable terminal ...
Shital K. Chattopadhyay +3 more
doaj +1 more source
A Relay Strategy Actuates Pre-Existing Trisubstituted Olefins in Monoterpenoids to Form New Trisubstituted Olefins by Cross Metathesis [PDF]
Karim A. Bahou +5 more
openalex +2 more sources
A hybrid of eugenol and a chalcone has been synthesized in good yield via cross olefin metathesis. The title compound (3) was characterized by spectroscopic data including NMR, infrared, and ESI-MS.
Muhamad S. Fareza +2 more
doaj +1 more source
MoO3 on zeolites MCM-22, MCM-56 and 2D-MFI as catalysts for 1-octene metathesis
Highly active olefin metathesis catalysts were prepared by thermal spreading MoO3 and/or MoO2(acac)2 on MWW zeolites (MCM-22, delaminated MCM-56) and on two-dimensional MFI (all in NH4+ form).
Hynek Balcar +3 more
doaj +1 more source
This account surveys the current progress on the application of intra- and intermolecular enyne metathesis as main key steps in the synthesis of challenging structural motifs and stereochemistries found in bioactive compounds.
Valerian Dragutan +3 more
doaj +1 more source
Why add another catalyst when the product itself holds the power to catalyze its own formation? Autocatalysis in synthetic chemistry enhances reaction efficiency and uncovers novel catalytic behavior across both closed‐shell and open‐shell systems, expanding reactivity and enabling innovative design strategies.
Jaspreet Kaur, Joshua P. Barham
wiley +1 more source

