Results 11 to 20 of about 3,099 (216)

Crotoxin Isolated from Crotalus durissus terrificus Venom Modulates the Functional Activity of Dendritic Cells via Formyl Peptide Receptors. [PDF]

J Immunol Res, 2018
The Crotalus durissus terrificus rattlesnake venom, its main toxin, crotoxin (CTX), and its crotapotin (CA) and phospholipase A2 (CB) subunits modulate the immune system.
Freitas AP, Favoretto BC, Clissa PB, Sampaio SC, Faquim-Mauro EL.   +4 more
europepmc   +3 more sources

Allopurinol reduces the lethality associated with acute renal failure induced by Crotalus durissus terrificus snake venom: comparison with probenecid. [PDF]

PLoS Neglected Tropical Diseases, 2011
BACKGROUND: Acute renal failure is one of the most serious complications of envenoming resulting from Crotalus durissus terrificus bites. This study evaluated the relevance of hyperuricemia and oxidative stress and the effects of allopurinol and ...
Rodrigo Frezzatti, Paulo Flavio Silveira
doaj   +4 more sources

Inflammasome NLRP3 activation induced by Convulxin, a C-type lectin-like isolated from Crotalus durissus terrificus snake venom. [PDF]

Sci Rep, 2022
Convulxin (CVX), a C-type lectin-like protein isolated from the venom of the snake species, Crotalus durissus terrificus, stimulates platelet aggregation by acting as a collagen receptor agonist for glycoprotein VI found in the platelets.
Rego CMA, Francisco AF, Boeno CN, Paloschi MV, Lopes JA, Silva MDS, Santana HM, Serrath SN, Rodrigues JE, Lemos CTL, Dutra RSS, da Cruz JN, Dos Santos CBR, da S Setúbal S, Fontes MRM, Soares AM, Pires WL, Zuliani JP.   +17 more
europepmc   +2 more sources

Chikungunya virus entry is strongly inhibited by phospholipase A2 isolated from the venom of Crotalus durissus terrificus. [PDF]

Sci Rep, 2021
Chikungunya virus (CHIKV) is the etiologic agent of Chikungunya fever, a globally spreading mosquito-borne disease. There is no approved antiviral or vaccine against CHIKV, highlighting an urgent need for novel therapies.
Santos IA, Shimizu JF, de Oliveira DM, Martins DOS, Cardoso-Sousa L, Cintra ACO, Aquino VH, Sampaio SV, Nicolau-Junior N, Sabino-Silva R, Merits A, Harris M, Jardim ACG.   +12 more
europepmc   +2 more sources

Evaluation of Protection by Caffeic Acid, Chlorogenic Acid, Quercetin and Tannic Acid against the In Vitro Neurotoxicity and In Vivo Lethality of Crotalus durissus terrificus (South American Rattlesnake) Venom. [PDF]

Toxins (Basel), 2021
Systemic envenomation by Crotalus durissus terrificus (South American rattlesnake) can cause coagulopathy, rabdomyolysis, acute kidney injury, and peripheral neuromuscular blockade, the latter resulting in flaccid paralysis.
Oliveira ICF, Yoshida EH, Dini MMJ, Paschoal ABO, Cogo JC, da Cruz-Höfling MA, Hyslop S, Oshima-Franco Y.   +7 more
europepmc   +2 more sources

Cytotoxic effects of crotoxin from Crotalus durissus terrificus snake in canine mammary tumor cell lines. [PDF]

J Venom Anim Toxins Incl Trop Dis
Background: Mammary gland tumors are the most prevalent neoplasm in intact female dogs, and they are good natural models to study comparative oncology. Most canine mammary malignancies, as in women, are commonly refractory to conventional therapies and ...
Pedro G, Brasileiro FCDS, Macedo JM, Soares AM, Mafra GC, Alves CEF, Laufer-Amorim R.   +6 more
europepmc   +2 more sources

Liver dysfunction in patients bitten by Crotalus durissus terrificus (Laurenti, 1768) snakes in Botucatu (State of São Paulo, Brazil) Alterações hepáticas em doentes picados por serpentes Crotalus durissus terrificus (Laurenti, 1768) na região de Botucatu, Estado de São Paulo, Brasil [PDF]

Revista do Instituto de Medicina Tropical de São Paulo, 1995
Thirty-two patients bitten by venomous snakes sixteen by Bothrops spp. and sixteen by Crotalus durissus terrificus were studied. The group comprised thirty males and two females, aged eight to sixty-three years (mean 33±15).
Benedito Barra Viera, Kunie Yabuki Rabello Coelho, Paulo Roberto Curi, Domingos Alves Meira   +3 more
doaj   +2 more sources

Afibrinogenemia following snake bite (Crotalus durissus terrificus) [PDF]

Revista do Instituto de Medicina Tropical de São Paulo, 1988
This paper reports two cases of afibrinogenemia with normal platelet count following Crotalus durissus terrificus, snake bite Both patients presented high output acute renal failure and case two also had increased blood levels of CPK and LDH compatible ...
C. F. S. Amaral, N. A. Rezende, T. M. G. Pedrosa, O. A. da Silva, E. R. P. Pedroso   +4 more
doaj   +3 more sources

Multiple effects of toxins isolated from Crotalus durissus terrificus on the hepatitis C virus life cycle. [PDF]

PLoS One, 2017
Hepatitis C virus (HCV) is one of the main causes of liver disease and transplantation worldwide. Current therapy is expensive, presents additional side effects and viral resistance has been described.
Shimizu JF, Pereira CM, Bittar C, Batista MN, Campos GRF, da Silva S, Cintra ACO, Zothner C, Harris M, Sampaio SV, Aquino VH, Rahal P, Jardim ACG.   +12 more
europepmc   +2 more sources

Random amplified polymorphisms between two South American subspecies of rattlesnakes (Crotalus durissus collilineatus and Crotalus durissus terrificus) [PDF]

Brazilian Archives of Biology and Technology, 2001
The present work was made to determine the suitability of RAPD analysis for the identification of specimens of two subspecies of South American rattlesnakes (Crotalus durissus terrificus and Crotalus durissus collilineatus).
Sergio Echeverrigaray, Gilberto Grazziotin, Felipe Grazziotin, Gustavo Agostini   +3 more
doaj   +4 more sources