Results 51 to 60 of about 3,099 (216)

Crotoxin-Induced Mice Lung Impairment: Role of Nicotinic Acetylcholine Receptors and COX-Derived Prostanoids

Biomolecules, 2020
Respiratory compromise in Crotalus durissus terrificus (C.d.t.) snakebite is an important pathological condition. Considering that crotoxin (CTX), a phospholipase A2 from C.d.t. venom, is the main component of the venom, the present work investigated the
Marco Aurelio Sartim, Camila O. S. Souza, Cassiano Ricardo A. F. Diniz, Vanessa M. B. da Fonseca, Lucas O. Sousa, Ana Paula F. Peti, Tassia Rafaella Costa, Alan G. Lourenço, Marcos C. Borges, Carlos A. Sorgi, Lucia Helena Faccioli, Suely Vilela Sampaio   +11 more
doaj   +1 more source

Kinetics of venom and antivenom serum levels, clinical evaluation and therapeutic effectiveness in dogs inoculated with Crotalus durissus terrificus venom

Journal of Venomous Animals and Toxins including Tropical Diseases, 2008
This work evaluated the clinical and therapeutic aspects as well as serum levels of venom and antivenom IgG by enzyme-linked immunosorbent assay (ELISA) in experimental envenomation of dogs with Crotalus durissus terrificus venom.
F. Sangiorgio, M. Sakate, R. M. B. Nogueira, J. P. Araújo JR., C. Chavez-Olortegui   +4 more
doaj   +1 more source

The venom of South American rattlesnakes inhibits macrophage functions and is endowed with anti-inflammatory properties

Mediators of Inflammation, 1996
The injection of Crotalus durissus terrificus venom into the foot pad of mice did not induce a significant inflammatory response as evaluated by oedema formation, increased vascular permeability and cell migration. The subcutaneous injection of the venom,
Maria C. C. de Sousa e Silva, Luis R. C. Gonçalves, Mario Mariano   +2 more
doaj   +1 more source

Laboratory evaluation of young ovines inoculated with natural or 60co-irradiated Crotalus durissus terrificus venom during hyperimmunization process

Journal of Venomous Animals and Toxins including Tropical Diseases, 2006
Laboratory profile of young ovines was studied in order to evaluate and compare their antiserum production from natural and Cobalt-60 irradiated Crotalus durissus terrificus (C.d.t.) venoms. The parameters analyzed included complete blood count, and urea,
R. S. Ferreira Junior, N. Nascimento, R. Couto, J. B. Alves, D. A. Meira, B. Barraviera   +5 more
doaj   +1 more source

Amphibia and Reptilia, Quebrada de los Cuervos, Departamento de Treinta y Tres, Uruguay [PDF]

Check List, 2011
We present an annotated list of the herpetofauna at the Protected Area Quebrada de los Cuervos, Departamento de Treinta y Tres, Uruguay. We recorded 24 species of amphibians and 29 of reptiles, accounting for near half of the species already reported ...
Carlos Prigioni, Claudio Borteiro, Francisco Kolenc   +2 more
doaj   +3 more sources

Autologous platelet‐rich plasma for healing chronic venous leg ulcers: Clinical efficacy and potential mechanisms

International Wound Journal, Volume 16, Issue 3, Page 788-792, June 2019., 2019
The overall quality of evidence of autologous platelet‐rich plasma (PRP) for treating chronic wounds remains low. While further well‐designed clinical studies are clearly required to convincingly demonstrate the efficacy of autologous PRP in improved healing of venous leg ulcers (VLUs) and other chronic wounds, there is also an increasing need to ...
Carolina D. Weller, Elizabeth E. Gardiner, Jane F. Arthur, Melissa Southey, Robert K. Andrews   +4 more
wiley   +1 more source

Clinical, Laboratory, and Therapeutic Aspects of Crotalus durissus (South American Rattlesnake) Victims: A Literature Review

BioMed Research International, Volume 2019, Issue 1, 2019., 2019
Snakebite envenoming is a neglected public health issue in many tropical and subtropical countries. To diagnosis and treat snakebites may be challenging to health care personnel since sufficient information has not been yet provided. This review presents the clinical, therapeutic, and laboratory aspects of Crotalus durissus (South American rattlesnakes)
Bruno Tumang Frare, Yann Keller Silva Resende, Bruno de Carvalho Dornelas, Miguel Tannus Jorge, Valter Augusto Souza Ricarte, Lívia Maria Alves, Luiz Fernando Moreira Izidoro, Giuseppe Piccione   +7 more
wiley   +1 more source

Biochemical comparison of venoms from young Colombian Crotalus durissus cumanensis and their parents

Journal of Venomous Animals and Toxins including Tropical Diseases, 2010
Crotalus durissus cumanensis, a rattlesnake endemic to Colombia and Venezuela, is considered one of the most lethal snake species in Latin America. The aim of the present study was to compare the protein content and biological activity of the venom ...
N Céspedes, F Castro, E Jiménez, L Montealegre, A Castellanos, CA Cañas, M Arévalo-Herrera, S Herrera   +7 more
doaj   +1 more source

Crotalus durissus ruruima Snake Venom and a Phospholipase A2 Isolated from This Venom Elicit Macrophages to Form Lipid Droplets and Synthesize Inflammatory Lipid Mediators

Journal of Immunology Research, Volume 2019, Issue 1, 2019., 2019
Viper snake Crotalus durissus ruruima (Cdr) is a subspecies found in northern area of Brazil. Among the snakes of Crotalus genus subspecies, the venom of Cdr presents highest level of crotoxin, which is the major component of Crotalus snake venoms, formed by two subunits (crotapotin and a phospholipase A2 named CBr) and presents potent neurotoxic ...
Ana Eduarda Zulim de Carvalho, Karina Giannotti, Elbio Leiguez Junior, Márcio Matsubara, Maria Cristina Dos Santos, Consuelo Latorre Fortes-Dias, Catarina Teixeira, Benoit Stijlemans   +7 more
wiley   +1 more source

Polymeric Nanoparticles for the Diagnosis and Treatment of Snakebite

Macromolecular Chemistry and Physics, Volume 227, Issue 1, 15 January 2026.
Snakebite envenomation affects between 1.8 and 5.5 million people annually, many of whom suffer disabilities or even death. Current antivenoms are composed of plasma‐derived antibodies. However, there remains an underexplored opportunity to utilise polymer‐based nanoparticles.
Neil Prabhakar, Thomas Oliver, Alexander N. Baker   +2 more
wiley   +1 more source