Results 131 to 140 of about 686 (159)

Systemic skeletal muscle necrosis induced by crotoxin

Toxicon, 2001
Systemic skeletal muscle necrosis induced by crotoxin, the major component of the venom of Crotalus durissus terrificus, was investigated. Mice received an intramuscular injection of crotoxin (0.35mg/kg body weight) into the right tibialis anterior (TA) muscles, which were evaluated 3h, 24h and 3 days later.
T F, Salvini, A C, Amaral, E H, Miyabara, J A, Turri, P M, Danella, H S, Selistre de Araújo   +5 more
openaire   +2 more sources

Effects of crotoxin on the isolated guinea pig heart

Toxicon, 1990
The effects of crotoxin, isolated from the venom of the South American rattlesnake, Crotalus durissus terrificus, were investigated on isolated guinea pig hearts, perfused with Locke solution, by the Langendorff method. The cardiac beats and the electrocardiogram were simultaneously registered and the creatine kinase (CK) activity of the perfusate ...
P E, Santos, S D, Souza, L, Freire-Maia, A P, Almeida   +3 more
openaire   +2 more sources

Muscle necrosis caused by the sub-units of crotoxin

Toxicon, 1986
The effects of the basic (CB) and acidic (CA) subunits of crotoxin on rat skeletal muscle in vivo have been studied. CB caused muscle necrosis, with damage limited to an outer rim of muscle fibres in rat soleus. The inflammatory response was relatively small.
J A, Kouyoumdjian, J B, Harris, M A, Johnson   +2 more
openaire   +2 more sources

Effects of subunit cross-linking on the properties of crotoxin

Toxicon, 1990
Crotoxin was cross-linked using 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride. Cross-linked crotoxin had the expected amino-terminal amino acids, amino acid composition, behavior on SDS-PAGE and an 80% reduction of reactable lysine residues.
B W, Lennon, D, Plummer, I I, Kaiser
openaire   +2 more sources

Postsynaptic Effects of Crotoxin and of Its Isolated Subunits

European Journal of Biochemistry, 1979
Crotoxin is a potent neurotoxin from the venom of Crotalus durissus terrificus. It is composed of two subunits: a basic phospholipase A2 with low toxicity (component B) and an acidic protein seemingly devoid of intrinsic biological activity (component A).
C, Bon, J P, Changeux, T W, Jeng, H, Fraenkel-Conrat   +3 more
openaire   +2 more sources

Crotoxin induces aggregation of human washed platelets

Toxicon, 1994
Crotoxin, the main toxic component isolated from the venom of the South American rattlesnake Crotalus durissus terrificus, is a reversible protein complex composed of a non-toxic non-enzymatic acidic polypeptide (crotapotin) and a toxic basic phospholipase A2 (PLA2).
E C, Landucci, A, Condino-Neto, A C, Perez, S, Hyslop, A P, Corrado, J C, Novello, S, Marangoni, B, Oliveira, E, Antunes, G, de Nucci   +9 more
openaire   +2 more sources

Crotoxin

Nature, 1939
K. H. SLOTTA, H. FRAENKEL-CONRAT
openaire   +1 more source

BIOLOGICAL ACTIVITIES OF CROTOXIN AND AMINO ACID SEQUENCE OF CROTOXIN B

1980
H. Fraenkel-Conrat, T-W. Jeng, M. Hsiang
openaire   +1 more source

Neutralization of crotoxin by the specific crotoxin inhibitor from Crotalus durissus terrificus serum

Toxicon, 1996
G. Faure, J. Perales, C. Villela, V. Choumet, B. Saliou, G.B. Domont, H. Moussatché, C. Bon   +7 more
openaire   +1 more source

Crotoxin: a diaphragm-specific myotoxin?

Toxicon, 1995
G.A. Canziani, M. Langford, L. Viskatis, J.C. Vidal, I. Kaiser   +4 more
openaire   +1 more source