Histopathological evaluation in experimental envenomation of dogs with Crotalus durissus terrificus venom [PDF]
Journal of Venomous Animals and Toxins including Tropical Diseases, 2008 The present work evaluated histopathological aspects in experimental envenomation of dogs with Crotalus durissus terrificus venom. Twenty-eight mixed breed adult dogs were divided into three groups of seven animals each: Group I - only venom; Group II ...
F. Sangiorgio +3 more
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Actions of Crotalus durissus terrificus venom and crotoxin on the isolated rat kidney [PDF]
Brazilian Journal of Medical and Biological Research, 2001 Many studies have reported the occurrence of lethal acute renal failure after snakebites. The aim of the present investigation was to determine alterations in renal function produced by Crotalus durissus terrificus venom and crotoxin as well as the ...
H.S.A. Monteiro +3 more
doaj +6 more sources
Revista da Sociedade Brasileira de Medicina Tropical, 2022 Snake toxins are widely studied owing to their importance in snakebite accidents, a serious public health issue in tropical countries, and their broad therapeutic potential.
Brunna Fernanda Arraez Alves +1 more
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Partial characterization of the venom of the Peruvian rattlesnake Crotalus durissus terrificus [PDF]
Revista Peruana de Biología, 2014 The venom of the rattlesnake Crotalus durissus terrificus from the region of Sandia, Puno, has been investigated for its protein content and some enzymatic activities, using for it the whole venom as well as the fractions obtained by gel filtration ...
César Remuzgo +3 more
doaj +5 more sources
Allopurinol Reduces the Lethality Associated with Acute Renal Failure Induced by Crotalus durissus terrificus Snake Venom: Comparison with Probenecid [PDF]
PLoS Neglected Tropical Diseases, 2011 BACKGROUND: Acute renal failure is one of the most serious complications of envenoming resulting from Crotalus durissus terrificus bites. This study evaluated the relevance of hyperuricemia and oxidative stress and the effects of allopurinol and ...
Paulo Flavio Silveira, Rodrigo Frezzatti
exaly +3 more sources
Local and systemic effects caused by Crotalus durissus terrificus, Crotalus durissus collilineatus, and Crotalus durissus cascavella snake venoms in swiss mice [PDF]
Revista da Sociedade Brasileira de Medicina Tropical, 2019 INTRODUCTION: Crotalus envenomations cause serious complications and can be fatal without appropriate treatment. Venom isoforms present and inter/intraspecific variations in the venom composition can result in different symptoms presented by bites by ...
Letícia Helena de Carvalho +13 more
doaj +7 more sources
Immunomodulatory properties of venom-derived crotamine [PDF]
Frontiers in PharmacologyCrotamine is a low-molecular-weight cationic polypeptide isolated from Crotalus durissus terrificus snake venom, classified as a non-enzymatic toxin with distinctive structural and functional properties. This toxin also exhibits characteristics of a cell-
Isadora Oliveira +5 more
doaj +2 more sources
Crotalus durissus terrificus venom as a source of antitumoral agents [PDF]
Journal of Venomous Animals and Toxins including Tropical Diseases, 2010 The basic knowledge on neoplasms is increasing quickly; however, few advances have been achieved in clinical therapy against tumors. For this reason, the development of alternative drugs is relevant in the attempt to improve prognosis and to increase ...
MA Soares +4 more
doaj +4 more sources
Crotoxin Isolated from Crotalus durissus terrificus Venom Modulates the Functional Activity of Dendritic Cells via Formyl Peptide Receptors. [PDF]
J Immunol Res, 2018 The Crotalus durissus terrificus rattlesnake venom, its main toxin, crotoxin (CTX), and its crotapotin (CA) and phospholipase A2 (CB) subunits modulate the immune system. Formyl peptide receptors (FPRs) and lipoxin A4 (LXA4) are involved in CTX’s effect on macrophages and neutrophils. Dendritic cells (DCs) are plasticity cells involved in the induction
Freitas AP +4 more
europepmc +2 more sources
In vitro activity of phospholipase A 2 and of peptides from Crotalus durissus terrificus venom against amastigote and promastigote forms of Leishmania (L.) infantum chagasi [PDF]
Journal of Venomous Animals and Toxins including Tropical Diseases, 2015 Background American visceral leishmaniasis is caused by the intracellular parasiteLeishmania (L.) infantum chagasi, and transmitted by the sand fly Lutzomyia longipalpis.
Gustavo A. C. Barros +7 more
doaj +2 more sources