Results 21 to 30 of about 35,250 (189)

Phenotypic dichotomy in Crotalus durissus ruruima venom and potential consequences for clinical management of snakebite envenomations. [PDF]

PLoS Neglected Tropical Diseases
BackgroundPhenotypic polymorphism in rattlesnake venoms is well-documented, with a dichotomy between hemorrhagic (Type I) and neurotoxic (Type II) venoms.
Mônica Colombini, Anderson M Rocha, Luciana A Freitas-de-Sousa, Alison F A Chaves, Solange M T Serrano, Vinicius C Souza, Vincent L Viala, Inácio L M Junqueira-Azevedo, Felipe A Cerni, Marco A Sartim, Jacqueline A G Sachett, Wuelton M Monteiro, Felipe G Grazziotin, Fan Hui Wen, Manuela B Pucca, Ana M Moura-da-Silva   +15 more
doaj   +2 more sources

Decoding Severity in Crotalic Snakebite Cases: Findings From a Decade of Cohort Analysis in Brazil. [PDF]

Biomed Res Int
Background Crotalic snakebite accidents are a common cause of admission into toxicology units in Brazil, and are associated with substantial morbidity and mortality. Our aim was to analyze clinical and laboratory findings, outcomes, and variables associated with the severity of patients treated for crotalic accidents at a reference center in Brazil ...
Silveira LRD, Ribeiro AJF, Chagas VS, Rosa PMDS, Silva JAC, Neves VFB, Andrade Filho A, Marcolino MS.   +7 more
europepmc   +2 more sources

Age-related biological activity of South American rattlesnake (Crotalus durissus terrificus) venom

Journal of Venomous Animals and Toxins including Tropical Diseases, 2003
An in vitro and in vivo comparative study was performed on the effects of Crotalus durissus terrificus venoms from a mother and its 15 newborns. The venoms were tested for protein content, lethality, proteolytic, myotoxic, hemorrhagic, and phospholipase ...
M. F. D. Furtado, M. C. Santos, A. S. Kamiguti   +2 more
doaj   +2 more sources

Single-step purification of crotapotin and crotactine from Crotalus durissus terrificus venom using preparative isoelectric focusing

Brazilian Journal of Medical and Biological Research, 1997
We describe the isolation of crotoxin, a presynaptic B-neurotoxin, as well as its subunits B (crotactine) and A (crotapotin) from lyophilized Crotalus durissus terrificus venom by a single-step preparative isoelectric focusing procedure.
A.S. Aguiar, A.R. Melgarejo, C.R. Alves, S. Giovanni-De-Simone   +3 more
doaj   +2 more sources

Acute hepatotoxicity of Crotalus durissus terrificus (South American rattlesnake) venom in rats

Journal of Venomous Animals and Toxins Including Tropical Diseases, 2009
Venom of the South American rattlesnake, Crotalus durissus terrificus (Cdt), presents myotoxic and neurotoxic outcomes, but reports on its effects on the liver are scarce.
RF França, RP Vieira, EF Ferrari, RA Souza, RAL Osorio, ACG Prianti-Jr, S Hyslop, SR Zamuner, JC Cogo, W Ribeiro   +9 more
exaly   +3 more sources

Bioprospection of rattlesnake venom peptide fractions with anti-adipose and anti-insulin resistance activity in vitro [PDF]

Toxicon: X
Animal venoms are natural products that have served as a source of novel molecules that have inspired novel drugs for several diseases, including for metabolic diseases such as type-2 diabetes and obesity. From venoms, toxins such as exendin-4 (Heloderma
David Meléndez-Martínez, Erika Ortega-Hernández, Edwin Estefan Reza-Zaldívar, Alejandro Carbajal-Saucedo, Gustavo Arnaud-Franco, Ana Gatica-Colima, Luis Fernando Plenge-Tellechea, Marilena Antunes-Ricardo, Daniel A. Jacobo-Velázquez, Karla Mayolo-Deloisa, Omar Lozano, Marco Rito-Palomares, Jorge Benavides   +12 more
doaj   +2 more sources

Biochemical and biological evaluation of gyroxin isolated from Crotalus durissus terrificus venom

Journal of Venomous Animals and Toxins Including Tropical Diseases, 2011
Gyroxin, a thrombin-like enzyme isolated from Crotalus durissus terrificus venom and capable of converting fibrinogen into fibrin, presents coagulant and neurotoxic activities.
Benedito Barraviera, Luciana Barros
exaly   +3 more sources

Crotalus durissus terrificus venom interferes with morphological, functional, and biochemical changes in murine macrophage. [PDF]

Mediators Inflamm, 2005
Crotalus durissus terrificus venom (Cdt) is toxic for a variety of eukaryotic cells, especially at high concentrations. However its effects on host immune cells are not well known. The purpose of this study was to determine the effect of Cdt on functional status and the mediators production in peritoneal macrophages. The effects of Cdt were analyzed in
Cruz AH, Mendonça RZ, Petricevich VL.
europepmc   +5 more sources

In vivo and in vitro prospection of the anti-ophidic properties exercised by the extracts of Jacaranda decurrens L.

Acta Scientiarum: Biological Sciences, 2021
The research and development of alternative treatments for snakebites (e.g., medicinal plants) is necessary due to the high costs of the existing ones.
Marcus Vinícius Cardoso Trento, Mateus Santos Carapiá, Pedro Henrique Souza César, Mariana Aparecida Braga, Andreimar Martins Soares, Silvana Marcussi   +5 more
doaj   +1 more source

The origin of the diversity of crotoxin isoforms in the venom of Crotalus durissus terrificus [PDF]

European Journal of Biochemistry, 1994
Crotoxin, the main toxin from the venom of the South American rattlesnake Crotalus durissus terrificus, is a β‐neurotoxin which consists of the non‐covalent association of two subunits: a phospholipase A2 subunit B (CB), and a non‐enzymic subunit A (CA).
G, Faure, V, Choumet, C, Bouchier, L, Camoin, J L, Guillaume, B, Monegier, M, Vuilhorgne, C, Bon   +7 more
openaire   +2 more sources