Results 41 to 50 of about 904 (174)

Lipases and proteases inhibition by Averrhoa carambola L. fruit extracts

Phytomedicine Plus, 2021
Background: Proteases and phospholipases A2 are involved in processes related to hemostasis. Medicinal plants which contain bioactive phytochemicals, can act as enzymatic modulators.
Daniela Aparecida Oliveira, Marcus Vinicius Cardoso Trento, Pedro Henrique Souza Cesar, Mariana Aparecida Braga, Silvana Marcussi   +4 more
doaj   +1 more source

Clinical, Laboratory, and Therapeutic Aspects of Crotalus durissus (South American Rattlesnake) Victims: A Literature Review

BioMed Research International, Volume 2019, Issue 1, 2019., 2019
Snakebite envenoming is a neglected public health issue in many tropical and subtropical countries. To diagnosis and treat snakebites may be challenging to health care personnel since sufficient information has not been yet provided. This review presents the clinical, therapeutic, and laboratory aspects of Crotalus durissus (South American rattlesnakes)
Bruno Tumang Frare, Yann Keller Silva Resende, Bruno de Carvalho Dornelas, Miguel Tannus Jorge, Valter Augusto Souza Ricarte, Lívia Maria Alves, Luiz Fernando Moreira Izidoro, Giuseppe Piccione   +7 more
wiley   +1 more source

Antivenomics as a tool to improve the neutralizing capacity of the crotalic antivenom: a study with crotamine

Journal of Venomous Animals and Toxins including Tropical Diseases, 2017
Background Snakebite treatment requires administration of an appropriate antivenom that should contain antibodies capable of neutralizing the venom. To achieve this goal, antivenom production must start from a suitable immunization protocol and proper ...
Ricardo Teixeira-Araújo, Patrícia Castanheira, Leonora Brazil-Más, Francisco Pontes, Moema Leitão de Araújo, Maria Lucia Machado Alves, Russolina Benedeta Zingali, Carlos Correa-Netto   +7 more
doaj   +1 more source

Spatial Structure Explains Morphological Variation Better Than Climatic Gradients in the South American Rattlesnake (Crotalus durissus)

Ecology and Evolution, Volume 16, Issue 3, March 2026.
We evaluated whether climatic gradients or spatial structure better explain body size variation in the South American rattlesnake (Crotalus durissus) across its wide geographic range. After explicitly accounting for spatial autocorrelation, climatic variables were not significant predictors of body size in either sex, whereas sex‐specific spatial ...
Mileny Otani, Henrique Caldeira Costa, Cláudio Henrique Zawadzki, Diego J. Santana   +3 more
wiley   +1 more source

Crotalus durissus ruruima Snake Venom and a Phospholipase A2 Isolated from This Venom Elicit Macrophages to Form Lipid Droplets and Synthesize Inflammatory Lipid Mediators

Journal of Immunology Research, Volume 2019, Issue 1, 2019., 2019
Viper snake Crotalus durissus ruruima (Cdr) is a subspecies found in northern area of Brazil. Among the snakes of Crotalus genus subspecies, the venom of Cdr presents highest level of crotoxin, which is the major component of Crotalus snake venoms, formed by two subunits (crotapotin and a phospholipase A2 named CBr) and presents potent neurotoxic ...
Ana Eduarda Zulim de Carvalho, Karina Giannotti, Elbio Leiguez Junior, Márcio Matsubara, Maria Cristina Dos Santos, Consuelo Latorre Fortes-Dias, Catarina Teixeira, Benoit Stijlemans   +7 more
wiley   +1 more source

Experimental envenomation with Crotalus durissus terrificus venom in dogs treated with antiophidic serum - part II: laboratory aspects, electrocardiogram and histopathology

Journal of Venomous Animals and Toxins including Tropical Diseases, 2007
The present work shows laboratory aspects, electrocardiogram and histopathology results during experimental envenomation by Crotalus durissus terrificus in dogs treated with antiophidic serum.
R. M. B. Nogueira, M. Sakate, F. Sangiorgio, C. B. Laposy, R. A. Tostes   +4 more
doaj   +1 more source

Combined Neuroprotective Effects of N,N‐Dimethyltryptamine and Ventral Root Reimplantation Following Spinal Root Avulsion in Rats

Journal of Neurochemistry, Volume 170, Issue 2, February 2026.
The ventral root avulsion (VRA) model provides an excellent experimental paradigm for studying injuries at the Central/Peripheral Nervous Systems (CNS/PNS) interface. By physically disconnecting motoneurons (MNs) from the spinal cord surface, VRA induces profound cellular, molecular, and functional deficits with limited spontaneous recovery.
Paola Andrea Caro Aponte, Edison Huertas Montoya, Italo O. Mazali, Alessandra Sussulini, Benedito Barraviera, Rui Seabra Ferreira Jr., Luciana Politti Cartarozzi, Alexandre Leite Rodrigues de Oliveira   +7 more
wiley   +1 more source

A rare case report of Russell's viper snakebite with ischemic stroke

Hong Kong Journal of Emergency Medicine, Volume 25, Issue 2, Page 95-97, March 2018., 2018
Ischemic stroke following snakebite is rare. We report a case of a 55‐year‐old male who developed headache with expressive aphasia following a Russell's viper bite. Computed tomography scan of the brain revealed infarcts in bilateral frontal lobes.
VK Pothukuchi, VR Chepuri, Kalyani Natta, Nagaraju Madigani, Alok Kumar   +4 more
wiley   +1 more source

Polymeric Nanoparticles for the Diagnosis and Treatment of Snakebite

Macromolecular Chemistry and Physics, Volume 227, Issue 1, 15 January 2026.
Snakebite envenomation affects between 1.8 and 5.5 million people annually, many of whom suffer disabilities or even death. Current antivenoms are composed of plasma‐derived antibodies. However, there remains an underexplored opportunity to utilise polymer‐based nanoparticles.
Neil Prabhakar, Thomas Oliver, Alexander N. Baker   +2 more
wiley   +1 more source

Natural Antispasmodics: Source, Stereochemical Configuration, and Biological Activity

BioMed Research International, Volume 2018, Issue 1, 2018., 2018
Natural products with antispasmodic activity have been used in traditional medicine to alleviate different illnesses since the remote past. We searched the literature and compiled the antispasmodic activity of 248 natural compounds isolated from terrestrial plants.
Edith Fabiola Martínez-Pérez, Zaida N. Juárez, Luis R. Hernández, Horacio Bach, Juergen Buenger   +4 more
wiley   +1 more source