Results 41 to 50 of about 35,250 (189)

Biochemical comparison of venoms from young Colombian Crotalus durissus cumanensis and their parents

Journal of Venomous Animals and Toxins including Tropical Diseases, 2010
Crotalus durissus cumanensis, a rattlesnake endemic to Colombia and Venezuela, is considered one of the most lethal snake species in Latin America. The aim of the present study was to compare the protein content and biological activity of the venom ...
N Céspedes, F Castro, E Jiménez, L Montealegre, A Castellanos, CA Cañas, M Arévalo-Herrera, S Herrera   +7 more
doaj   +1 more source

The First Anti-Snakebite and Hepatoprotective Characterization of a Trypsin Kunitz-like Inhibitor (EcTI) from the Plant Enterolobium contortisiliquum; A Case of Two Soul Mates Meeting

Pharmaceuticals, 2023
Snake venom serine protease (SVSP) interferes with the regulation and control of important biological reactions in homeostasis and can be classified as an activator of the fibrinolytic system and platelet aggregation.
Caroline R. C. Costa, Mariana N. Belchor, Airam Roggero, Laila L. Moraes, Ricardo Samelo, Isabelly Annunciato, Camila R. Bonturi, Maria L. V. Oliva, Sergio F. Sousa, Marcos A. de Oliveira, Marcos H. Toyama   +10 more
doaj   +1 more source

Avaliação em camundongo da eficácia do antiveneno administrado no local da inoculação intramuscular do veneno de Crotalus durissus terrificus Evaluation in mice, of the antivenom efficacy injected at the same place of the intramuscular inoculation of the Crotalus durissus terrificus venom

Revista do Instituto de Medicina Tropical de São Paulo, 1993
A eficácia do antiveneno crotálico por via intramuscular (im) no local da inoculação, também im, do veneno de Crotalus durissus terrificus foi avaliada em camundongos.
Lindioneza Adriano Ribeiro, Carla Lilian Agostini Utescher, Silvia Lucia Paro Vieira, Sara Fensterseifer, Helena Mukuno, Miguel Tanús Jorge   +5 more
doaj   +1 more source

Preliminary Insights of Brazilian Snake Venom Metalloproteomics

Toxins, 2023
Snakebite envenoming is one of the most significantly neglected tropical diseases in the world. The lack of diagnosis/prognosis methods for snakebite is one of our motivations to develop innovative technological solutions for Brazilian health.
Bruna Cavecci-Mendonça, Karen Monique Luciano, Tauane Vaccas, Laudicéia Alves de Oliveira, Eloisa Fornaro Clemente, Bruno Cesar Rossini, José Cavalcante Souza Vieira, Luciana Curtolo de Barros, Ilka Biondi, Pedro de Magalhães Padilha, Lucilene Delazari dos Santos   +10 more
doaj   +1 more source

Lipases and proteases inhibition by Averrhoa carambola L. fruit extracts

Phytomedicine Plus, 2021
Background: Proteases and phospholipases A2 are involved in processes related to hemostasis. Medicinal plants which contain bioactive phytochemicals, can act as enzymatic modulators.
Daniela Aparecida Oliveira, Marcus Vinicius Cardoso Trento, Pedro Henrique Souza Cesar, Mariana Aparecida Braga, Silvana Marcussi   +4 more
doaj   +1 more source

Autologous platelet‐rich plasma for healing chronic venous leg ulcers: Clinical efficacy and potential mechanisms

International Wound Journal, Volume 16, Issue 3, Page 788-792, June 2019., 2019
The overall quality of evidence of autologous platelet‐rich plasma (PRP) for treating chronic wounds remains low. While further well‐designed clinical studies are clearly required to convincingly demonstrate the efficacy of autologous PRP in improved healing of venous leg ulcers (VLUs) and other chronic wounds, there is also an increasing need to ...
Carolina D. Weller, Elizabeth E. Gardiner, Jane F. Arthur, Melissa Southey, Robert K. Andrews   +4 more
wiley   +1 more source

Clinical, Laboratory, and Therapeutic Aspects of Crotalus durissus (South American Rattlesnake) Victims: A Literature Review

BioMed Research International, Volume 2019, Issue 1, 2019., 2019
Snakebite envenoming is a neglected public health issue in many tropical and subtropical countries. To diagnosis and treat snakebites may be challenging to health care personnel since sufficient information has not been yet provided. This review presents the clinical, therapeutic, and laboratory aspects of Crotalus durissus (South American rattlesnakes)
Bruno Tumang Frare, Yann Keller Silva Resende, Bruno de Carvalho Dornelas, Miguel Tannus Jorge, Valter Augusto Souza Ricarte, Lívia Maria Alves, Luiz Fernando Moreira Izidoro, Giuseppe Piccione   +7 more
wiley   +1 more source

Spatial Structure Explains Morphological Variation Better Than Climatic Gradients in the South American Rattlesnake (Crotalus durissus)

Ecology and Evolution, Volume 16, Issue 3, March 2026.
We evaluated whether climatic gradients or spatial structure better explain body size variation in the South American rattlesnake (Crotalus durissus) across its wide geographic range. After explicitly accounting for spatial autocorrelation, climatic variables were not significant predictors of body size in either sex, whereas sex‐specific spatial ...
Mileny Otani, Henrique Caldeira Costa, Cláudio Henrique Zawadzki, Diego J. Santana   +3 more
wiley   +1 more source

Crotalus durissus ruruima Snake Venom and a Phospholipase A2 Isolated from This Venom Elicit Macrophages to Form Lipid Droplets and Synthesize Inflammatory Lipid Mediators

Journal of Immunology Research, Volume 2019, Issue 1, 2019., 2019
Viper snake Crotalus durissus ruruima (Cdr) is a subspecies found in northern area of Brazil. Among the snakes of Crotalus genus subspecies, the venom of Cdr presents highest level of crotoxin, which is the major component of Crotalus snake venoms, formed by two subunits (crotapotin and a phospholipase A2 named CBr) and presents potent neurotoxic ...
Ana Eduarda Zulim de Carvalho, Karina Giannotti, Elbio Leiguez Junior, Márcio Matsubara, Maria Cristina Dos Santos, Consuelo Latorre Fortes-Dias, Catarina Teixeira, Benoit Stijlemans   +7 more
wiley   +1 more source

Antivenomics as a tool to improve the neutralizing capacity of the crotalic antivenom: a study with crotamine

Journal of Venomous Animals and Toxins including Tropical Diseases, 2017
Background Snakebite treatment requires administration of an appropriate antivenom that should contain antibodies capable of neutralizing the venom. To achieve this goal, antivenom production must start from a suitable immunization protocol and proper ...
Ricardo Teixeira-Araújo, Patrícia Castanheira, Leonora Brazil-Más, Francisco Pontes, Moema Leitão de Araújo, Maria Lucia Machado Alves, Russolina Benedeta Zingali, Carlos Correa-Netto   +7 more
doaj   +1 more source