Results 51 to 60 of about 904 (174)

Decoding Severity in Crotalic Snakebite Cases: Findings From a Decade of Cohort Analysis in Brazil

BioMed Research International, Volume 2026, Issue 1, 2026.
Background Crotalic snakebite accidents are a common cause of admission into toxicology units in Brazil, and are associated with substantial morbidity and mortality. Our aim was to analyze clinical and laboratory findings, outcomes, and variables associated with the severity of patients treated for crotalic accidents at a reference center in Brazil ...
Luciana Reis da Silveira, Aloisio Joaquim Freitas Ribeiro, Victor Schulthais Chagas, Patryk Marques da Silva Rosa, Julia Alpino de Castro Silva, Victoria Fialho Baroni Neves, Adebal de Andrade Filho, Milena Soriano Marcolino, Poorani Gurumallesh Prabu   +8 more
wiley   +1 more source

Jabuticaba (Plinia jaboticaba) skin extracts as inhibitors of phospholipases A2 and proteases

Anais da Academia Brasileira de Ciências
: The phenolic extracts of jabuticaba skin flour (JSF) were characterized by HPLC, and evaluated for their modulating action upon phospholipases A2 and proteases of snake venom, aiming at their possible use in the treatment of the various diseases ...
TAMARA R. MARQUES, MARIANA A. BRAGA, PEDRO H.S. CESAR, SILVANA MARCUSSI, ANGELITA D. CORRÊA   +4 more
doaj   +1 more source

Comparison of wildlife and captivity rattlesnakes (Crotalus durissus terrificus) microbiota Comparação da microbiota de cascavéis (Crotalus durissus terrificus) de vida-livre e cativeiro

Pesquisa Veterinária Brasileira, 2009
The study evaluated and compared the aerobic microbiota from the oral cavity, cloaca and venom of Crotalus durissus terrificus snakes, recently caught from the wild and kept under quarantine (WQ), individual captivity (IC) and collective captivity (CC ...
Rui S. Ferreira Junior, Amanda K. Siqueira, Michelle V. Campagner, Tatiana Salerno, Taíssa C.S. Soares, Simone B. Lucheis, Antonio C. Paes, Benedito Barraviera   +7 more
doaj   +1 more source

Animal Venoms as Peptide Libraries for the Discovery of Antiglioblastoma Agents

Biochemistry Research International, Volume 2026, Issue 1, 2026.
Glioblastoma is one of the most aggressive and widely recognized types of brain tumors, characterized by significant cellular and molecular diversity and an inherently aggressive nature. The treatment remains highly challenging, with limited effectiveness and persistently low survival rates.
Livia Ramos Santiago, Edgar Alejandro Pinos Tamayo, Daniel Moreira dos Santos, Bonglee Kim, José R. Almeida, Rosy Iara Maciel de Azambuja Ribeiro, Marco Eigenfeld   +6 more
wiley   +1 more source

Age-related biological activity of South American rattlesnake (Crotalus durissus terrificus) venom

Journal of Venomous Animals and Toxins including Tropical Diseases, 2003
An in vitro and in vivo comparative study was performed on the effects of Crotalus durissus terrificus venoms from a mother and its 15 newborns. The venoms were tested for protein content, lethality, proteolytic, myotoxic, hemorrhagic, and phospholipase ...
M. F. D. Furtado, M. C. Santos, A. S. Kamiguti   +2 more
doaj   +1 more source

The Proteome of African Spitting and Non‐Spitting Cobra Venoms and Cytotoxicity Against Pancreatic Cancer Cells

Journal of Applied Toxicology, Volume 45, Issue 10, Page 2055-2067, October 2025.
ABSTRACT African cobra (Naja spp.) venom contains toxins dominated by proteins and peptides with inter‐ and intra‐specific variations. There are several FDA‐approved drugs from snake venom toxins from other regions, including South America and Asia. Profiling the proteomes of medically important African cobra venoms from different locations will aid in
Benedict C. Offor, Beric Muller, Lesetja R. Motadi, Lizelle A. Piater   +3 more
wiley   +1 more source

Effects of 60Co gamma radiation on crotamine

Brazilian Journal of Medical and Biological Research, 2001
Ionizing radiation can change the molecular structure and affect the biological properties of biomolecules. This has been employed to attenuate animal toxins.
M. Boni-Mitake, H. Costa, P.J. Spencer, V.S. Vassilieff, J.R. Rogero   +4 more
doaj   +1 more source

Prey specificity of predatory venoms

Biological Reviews, Volume 99, Issue 6, Page 2253-2273, December 2024.
ABSTRACT Venom represents a key adaptation of many venomous predators, allowing them to immobilise prey quickly through chemical rather than physical warfare. Evolutionary arms races between prey and a predator are believed to be the main factor influencing the potency and composition of predatory venoms.
Ondřej Michálek, Glenn F. King, Stano Pekár   +2 more
wiley   +1 more source

Identification, description and structural analysis of beta phospholipase A2 inhibitors (sbβPLIs) from Latin American pit vipers indicate a binding site region for basic snake venom phospholipases A2

Toxicon: X, 2019
Several snake species possess, in their circulating blood, endogenous PLA2 inhibitors (sbPLIs) with the primary function of natural protection against toxic enzymes from homologous and heterologous venoms.
Consuelo Latorre Fortes-Dias, Carlos Alexandre H. Fernandes, Paula Ladeira Ortolani, Patrícia Cota Campos, L.A. Melo, Liza Figueiredo Felicori, Marcos Roberto M. Fontes   +6 more
doaj   +1 more source

Snake venom toxins: Potential anticancer therapeutics

Journal of Applied Toxicology, Volume 44, Issue 5, Page 666-685, May 2024.
Abstract Snake venom contains a cocktail of compounds dominated by proteins and peptides, which make up the toxin. The toxin components of snake venom attack several targets in the human body including the neuromuscular system, kidney and blood coagulation system and cause pathologies. As such, the venom toxins can be managed and used for the treatment
Benedict C. Offor, Lizelle A. Piater
wiley   +1 more source