Results 61 to 70 of about 35,250 (189)

The Proteome of African Spitting and Non‐Spitting Cobra Venoms and Cytotoxicity Against Pancreatic Cancer Cells

Journal of Applied Toxicology, Volume 45, Issue 10, Page 2055-2067, October 2025.
ABSTRACT African cobra (Naja spp.) venom contains toxins dominated by proteins and peptides with inter‐ and intra‐specific variations. There are several FDA‐approved drugs from snake venom toxins from other regions, including South America and Asia. Profiling the proteomes of medically important African cobra venoms from different locations will aid in
Benedict C. Offor, Beric Muller, Lesetja R. Motadi, Lizelle A. Piater   +3 more
wiley   +1 more source

Prey specificity of predatory venoms

Biological Reviews, Volume 99, Issue 6, Page 2253-2273, December 2024.
ABSTRACT Venom represents a key adaptation of many venomous predators, allowing them to immobilise prey quickly through chemical rather than physical warfare. Evolutionary arms races between prey and a predator are believed to be the main factor influencing the potency and composition of predatory venoms.
Ondřej Michálek, Glenn F. King, Stano Pekár   +2 more
wiley   +1 more source

Effects of 60Co gamma radiation on crotamine

Brazilian Journal of Medical and Biological Research, 2001
Ionizing radiation can change the molecular structure and affect the biological properties of biomolecules. This has been employed to attenuate animal toxins.
M. Boni-Mitake, H. Costa, P.J. Spencer, V.S. Vassilieff, J.R. Rogero   +4 more
doaj   +1 more source

Snake venom toxins: Potential anticancer therapeutics

Journal of Applied Toxicology, Volume 44, Issue 5, Page 666-685, May 2024.
Abstract Snake venom contains a cocktail of compounds dominated by proteins and peptides, which make up the toxin. The toxin components of snake venom attack several targets in the human body including the neuromuscular system, kidney and blood coagulation system and cause pathologies. As such, the venom toxins can be managed and used for the treatment
Benedict C. Offor, Lizelle A. Piater
wiley   +1 more source

The Protective Action of Coutarea hexandra (Rubiaceae) on the Neuromuscular Blockade Induced by Lachesis muta muta (Viperidae: Crotalinae) Venom

BioMed Research International, Volume 2024, Issue 1, 2024.
Envenomations by snakes represent a neglected health problem in tropical and subtropical countries. In South America, Lachesis muta occasionally causes severe human envenomation, with treatment being conditioned to an unspecific antivenom. In this work, we examined the neutralizing ability of Coutarea hexandra stem bark hydroalcoholic extract (Ch‐E ...
Grazielle D. Pilon, Anna P. Farias-de-França, Nathalia M. Cantuária, Magali G. Silva, Aline G. Leão-Torres, Rafael S. Floriano, Marcio G. dos Santos, Nelson Jorge da Silva Jr., Otto M. S. Gerlach, Valdir Cechinel-Filho, Yoko Oshima-Franco, Samuele Maramai   +11 more
wiley   +1 more source

ACUTE HEPATOTOXICITY OF Crotalus durissus terrificus (SOUTH AMERICAN RATTLESNAKE) VENOM IN RATS [PDF]

, 2015
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Venom of the South American rattlesnake, Crotalus durissus terrificus (Cdt), presents myotoxic and neurotoxic outcomes, but reports on its effects on the liver are scarce.
Prianti-Jr, ACG, Hyslop, S, Ribeiro, W, Souza, RA, Franca, RF, Zamuner, SR, Cogo, JC, Osorio, RAL, Ferrari, EF, Vieira, RP   +9 more
core  

Crotacetin, a novel snake venom C-type lectin, is homolog of convulxin

Journal of Venomous Animals and Toxins including Tropical Diseases, 2005
Snake venom (sv) C-type lectins encompass a group of hemorrhagic toxins, which are able to interfere with hemostasis. They share significant similarity in their primary structures with C-type lectins of other animals, and also present a conserved ...
G. Rádis-Baptista, F. B. M. B. Moreno, L. L. Nogueira, A. M. C. Martins, D. O. Toyama, M. H. Toyama, W. F. Azevedo Jr, B. S. Cavada, T. Yamane   +8 more
doaj   +1 more source

Bilateral posterior circulation stroke secondary to a crotalid envenomation: case report

Revista da Sociedade Brasileira de Medicina Tropical, 2013
Snake bite envenoming is a disease with potential serious neurological complications. We report a case of an adolescent who was bitten by a rattlesnake and developed bilateral posterior circulation stroke.
Thiago Cardoso Vale, Alysson Ferreira Leite, Priscila Ribeiro da Hora, Marayra Inês França Coury, Ricardo Cipriano da Silva, Antônio Lúcio Teixeira   +5 more
doaj   +3 more sources

Identification, description and structural analysis of beta phospholipase A2 inhibitors (sbβPLIs) from Latin American pit vipers indicate a binding site region for basic snake venom phospholipases A2

Toxicon: X, 2019
Several snake species possess, in their circulating blood, endogenous PLA2 inhibitors (sbPLIs) with the primary function of natural protection against toxic enzymes from homologous and heterologous venoms.
Consuelo Latorre Fortes-Dias, Carlos Alexandre H. Fernandes, Paula Ladeira Ortolani, Patrícia Cota Campos, L.A. Melo, Liza Figueiredo Felicori, Marcos Roberto M. Fontes   +6 more
doaj   +1 more source

A eficácia do antiveneno botrópico-crotálico na neutralização das principais atividades do veneno de Bothrops jararacussu The efficacy of the bothropic/crotalic antivenom on the neutralization of the main Bothrops jararacussu venom activities

Revista do Instituto de Medicina Tropical de São Paulo, 1992
A mionecrose é um dos efeitos causados pelo veneno de Bothrops jararacussu. Uma miotoxina com homologia estrutural à fosfolipase A2 (PLA2), mas sem atividade enzimática, foi isolada desse veneno.
Maria Cristina dos-Santos, Luís Roberto de Camargo Gonçalves, Consuelo L. Fortes-Dias, Yara Cury, José Maria Gutiérrez, Maria de Fátima D. Furtado   +5 more
doaj   +1 more source