Results 61 to 70 of about 904 (174)

A eficácia do antiveneno botrópico-crotálico na neutralização das principais atividades do veneno de Bothrops jararacussu The efficacy of the bothropic/crotalic antivenom on the neutralization of the main Bothrops jararacussu venom activities

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 1992
A mionecrose é um dos efeitos causados pelo veneno de Bothrops jararacussu. Uma miotoxina com homologia estrutural à fosfolipase A2 (PLA2), mas sem atividade enzimática, foi isolada desse veneno.
Maria Cristina dos-Santos   +5 more
doaj   +1 more source

Kinetic characterization of gyroxin, a serine protease from Crotalus durissus terrificus venom

open access: yesBiochimie, 2012
This work describes for the first time the characterization of the enzymatic features of gyroxin, a serine protease from Crotalus durissus terrificus venom, capable to induce barrel rotation syndrome in rodents. Measuring the hydrolysis of the substrate ZFR-MCA, the optimal pH for proteolytic cleavage of gyroxin was found to be at pH 8.4.
Yonamine, Camila Miyagui UNIFESP   +10 more
openaire   +3 more sources

The Protective Action of Coutarea hexandra (Rubiaceae) on the Neuromuscular Blockade Induced by Lachesis muta muta (Viperidae: Crotalinae) Venom

open access: yesBioMed Research International, Volume 2024, Issue 1, 2024.
Envenomations by snakes represent a neglected health problem in tropical and subtropical countries. In South America, Lachesis muta occasionally causes severe human envenomation, with treatment being conditioned to an unspecific antivenom. In this work, we examined the neutralizing ability of Coutarea hexandra stem bark hydroalcoholic extract (Ch‐E ...
Grazielle D. Pilon   +11 more
wiley   +1 more source

Bilateral posterior circulation stroke secondary to a crotalid envenomation: case report

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2013
Snake bite envenoming is a disease with potential serious neurological complications. We report a case of an adolescent who was bitten by a rattlesnake and developed bilateral posterior circulation stroke.
Thiago Cardoso Vale   +5 more
doaj   +3 more sources

Crotacetin, a novel snake venom C-type lectin, is homolog of convulxin

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2005
Snake venom (sv) C-type lectins encompass a group of hemorrhagic toxins, which are able to interfere with hemostasis. They share significant similarity in their primary structures with C-type lectins of other animals, and also present a conserved ...
G. Rádis-Baptista   +8 more
doaj   +1 more source

Neutralization of the effect of Crotalus durissus terrificus venom by gangliosides.

open access: yesBrazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica, 1996
We determined the ability of a mixture of gangliosides (16% GD1b, 19% GT1b, 21% GM1, 40% GD1a) to neutralize the effect of Crotalus durissus terrificus (Cdt) venom in vitro and in vivo. Protection was indicated by the absence of muscular contractions, hind limb paralysis or death of BALB/c mice (16-18 g) after receiving Cdt venom (1 microgram Cdt venom
M D, Vancetto, L C, Curi, C A, Pereira
openaire   +1 more source

Crotalus durissus terrificus crotapotin naturally displays preferred positions for amino acid substitutions

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2017
Background Classically, Crotalus durissus terrificus (Cdt) venom can be described, according to chromatographic criteria, as a simple venom, composed of four major toxins, namely: gyroxin, crotamine, crotoxin and convulxin.
Laudicéia Alves de Oliveira   +6 more
doaj   +1 more source

Single-step purification of crotapotin and crotactine from Crotalus durissus terrificus venom using preparative isoelectric focusing

open access: yesBrazilian Journal of Medical and Biological Research, 1997
We describe the isolation of crotoxin, a presynaptic B-neurotoxin, as well as its subunits B (crotactine) and A (crotapotin) from lyophilized Crotalus durissus terrificus venom by a single-step preparative isoelectric focusing procedure.
A.S. Aguiar   +3 more
doaj   +1 more source

Antivenom against Crotalus durissus terrificus venom: Immunochemical reactivity and experimental neutralizing capacity

open access: yesToxicon, 2017
The venom of Crotalus durissus terrificus produces a neurotoxic and myotoxic syndrome that can lead to the death. Specific antivenom is the only treatment to neutralize the toxicity of the venom and the precocity in applying the antivenom is crucial for the efficiency of the treatment.
Baudou, F. G.   +6 more
openaire   +4 more sources

Clinical and hematological alterations in dogs during experimental envenomation with Crotalus durissus terrificus venom and treated with antiophidic serum

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2006
The present work aimed to evaluate the clinical and hematological aspects during experimental envenomation by Crotalus durissus terrificus in dogs treated with different antiophidic serum doses.
R. M. B. Nogueira, M. Sakate
doaj   +1 more source

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