Results 61 to 70 of about 904 (174)
A mionecrose é um dos efeitos causados pelo veneno de Bothrops jararacussu. Uma miotoxina com homologia estrutural à fosfolipase A2 (PLA2), mas sem atividade enzimática, foi isolada desse veneno.
Maria Cristina dos-Santos +5 more
doaj +1 more source
Kinetic characterization of gyroxin, a serine protease from Crotalus durissus terrificus venom
This work describes for the first time the characterization of the enzymatic features of gyroxin, a serine protease from Crotalus durissus terrificus venom, capable to induce barrel rotation syndrome in rodents. Measuring the hydrolysis of the substrate ZFR-MCA, the optimal pH for proteolytic cleavage of gyroxin was found to be at pH 8.4.
Yonamine, Camila Miyagui UNIFESP +10 more
openaire +3 more sources
Envenomations by snakes represent a neglected health problem in tropical and subtropical countries. In South America, Lachesis muta occasionally causes severe human envenomation, with treatment being conditioned to an unspecific antivenom. In this work, we examined the neutralizing ability of Coutarea hexandra stem bark hydroalcoholic extract (Ch‐E ...
Grazielle D. Pilon +11 more
wiley +1 more source
Bilateral posterior circulation stroke secondary to a crotalid envenomation: case report
Snake bite envenoming is a disease with potential serious neurological complications. We report a case of an adolescent who was bitten by a rattlesnake and developed bilateral posterior circulation stroke.
Thiago Cardoso Vale +5 more
doaj +3 more sources
Crotacetin, a novel snake venom C-type lectin, is homolog of convulxin
Snake venom (sv) C-type lectins encompass a group of hemorrhagic toxins, which are able to interfere with hemostasis. They share significant similarity in their primary structures with C-type lectins of other animals, and also present a conserved ...
G. Rádis-Baptista +8 more
doaj +1 more source
Neutralization of the effect of Crotalus durissus terrificus venom by gangliosides.
We determined the ability of a mixture of gangliosides (16% GD1b, 19% GT1b, 21% GM1, 40% GD1a) to neutralize the effect of Crotalus durissus terrificus (Cdt) venom in vitro and in vivo. Protection was indicated by the absence of muscular contractions, hind limb paralysis or death of BALB/c mice (16-18 g) after receiving Cdt venom (1 microgram Cdt venom
M D, Vancetto, L C, Curi, C A, Pereira
openaire +1 more source
Background Classically, Crotalus durissus terrificus (Cdt) venom can be described, according to chromatographic criteria, as a simple venom, composed of four major toxins, namely: gyroxin, crotamine, crotoxin and convulxin.
Laudicéia Alves de Oliveira +6 more
doaj +1 more source
We describe the isolation of crotoxin, a presynaptic B-neurotoxin, as well as its subunits B (crotactine) and A (crotapotin) from lyophilized Crotalus durissus terrificus venom by a single-step preparative isoelectric focusing procedure.
A.S. Aguiar +3 more
doaj +1 more source
The venom of Crotalus durissus terrificus produces a neurotoxic and myotoxic syndrome that can lead to the death. Specific antivenom is the only treatment to neutralize the toxicity of the venom and the precocity in applying the antivenom is crucial for the efficiency of the treatment.
Baudou, F. G. +6 more
openaire +4 more sources
The present work aimed to evaluate the clinical and hematological aspects during experimental envenomation by Crotalus durissus terrificus in dogs treated with different antiophidic serum doses.
R. M. B. Nogueira, M. Sakate
doaj +1 more source

