Results 31 to 40 of about 904 (174)

The venom of South American rattlesnakes inhibits macrophage functions and is endowed with anti-inflammatory properties

Mediators of Inflammation, 1996
The injection of Crotalus durissus terrificus venom into the foot pad of mice did not induce a significant inflammatory response as evaluated by oedema formation, increased vascular permeability and cell migration. The subcutaneous injection of the venom,
Maria C. C. de Sousa e Silva, Luis R. C. Gonçalves, Mario Mariano   +2 more
doaj   +1 more source

Laboratory evaluation of young ovines inoculated with natural or 60co-irradiated Crotalus durissus terrificus venom during hyperimmunization process

Journal of Venomous Animals and Toxins including Tropical Diseases, 2006
Laboratory profile of young ovines was studied in order to evaluate and compare their antiserum production from natural and Cobalt-60 irradiated Crotalus durissus terrificus (C.d.t.) venoms. The parameters analyzed included complete blood count, and urea,
R. S. Ferreira Junior, N. Nascimento, R. Couto, J. B. Alves, D. A. Meira, B. Barraviera   +5 more
doaj   +1 more source

EVALUATION OF THE ANTIBACTERIAL ACTIVITY OF Crotalus durissus terrificus CRUDE VENOM [PDF]

Ciência Animal Brasileira, 2018
Abstract Snake venoms are recognized as a promising source of pharmacologically active substances and are potentially useful for the development of new antimicrobial drugs. This study aimed to investigate the antimicrobial activity of the venom from the rattlesnake Crotalus durissus terrificus against several bacteria.
Dietz, Jefferson do Carmo, Almeida, Daniela Andrade de, Cintra, Lorena Cardoso, Oliveira, Bruno Francesco Rodrigues de, Magalhães, Marta Regina, Jesuíno, Rosália Santos Amorim   +5 more
openaire   +3 more sources

Biochemical comparison of venoms from young Colombian Crotalus durissus cumanensis and their parents

Journal of Venomous Animals and Toxins including Tropical Diseases, 2010
Crotalus durissus cumanensis, a rattlesnake endemic to Colombia and Venezuela, is considered one of the most lethal snake species in Latin America. The aim of the present study was to compare the protein content and biological activity of the venom ...
N Céspedes, F Castro, E Jiménez, L Montealegre, A Castellanos, CA Cañas, M Arévalo-Herrera, S Herrera   +7 more
doaj   +1 more source

Cytoskeleton, endoplasmic reticulum and nucleus alterations in CHO-K1 cell line after Crotalus durissus terrificus (South American rattlesnake) venom treatment

Journal of Venomous Animals and Toxins including Tropical Diseases, 2007
Snake venoms are toxic to a variety of cell types. However, the intracellular damages and the cell death fate induced by venom are unclear. In the present work, the action of the South American rattlesnake Crotalus durissus terrificus venom on CHO-K1 ...
B. P. Tamieti, R. A. Damatta, J. C. Cogo, N. S. Da Silva, J. Mittmann, C. Pacheco-Soares   +5 more
doaj   +1 more source

The First Anti-Snakebite and Hepatoprotective Characterization of a Trypsin Kunitz-like Inhibitor (EcTI) from the Plant Enterolobium contortisiliquum; A Case of Two Soul Mates Meeting

Pharmaceuticals, 2023
Snake venom serine protease (SVSP) interferes with the regulation and control of important biological reactions in homeostasis and can be classified as an activator of the fibrinolytic system and platelet aggregation.
Caroline R. C. Costa, Mariana N. Belchor, Airam Roggero, Laila L. Moraes, Ricardo Samelo, Isabelly Annunciato, Camila R. Bonturi, Maria L. V. Oliva, Sergio F. Sousa, Marcos A. de Oliveira, Marcos H. Toyama   +10 more
doaj   +1 more source

Role of crotoxin, a phospholipase A2 isolated from Crotalus durissus terrificus snake venom, on inflammatory and immune reactions

Mediators of Inflammation, 2001
Background: Crotoxin (CTX) is a potent neurotoxin from Crotalus durissus terrificus snake venom (CdtV) composed of two subunits: one without catalytic activity (crotapotin), and a basic phospolipase A2.
Diva F. Cardoso, Monica Lopes-Ferreira, Eliana L. Faquim-Mauro, Mahasti S. Macedo, Sandra H. P. Farsky   +4 more
doaj   +1 more source

Avaliação em camundongo da eficácia do antiveneno administrado no local da inoculação intramuscular do veneno de Crotalus durissus terrificus Evaluation in mice, of the antivenom efficacy injected at the same place of the intramuscular inoculation of the Crotalus durissus terrificus venom

Revista do Instituto de Medicina Tropical de São Paulo, 1993
A eficácia do antiveneno crotálico por via intramuscular (im) no local da inoculação, também im, do veneno de Crotalus durissus terrificus foi avaliada em camundongos.
Lindioneza Adriano Ribeiro, Carla Lilian Agostini Utescher, Silvia Lucia Paro Vieira, Sara Fensterseifer, Helena Mukuno, Miguel Tanús Jorge   +5 more
doaj   +1 more source

Preliminary Insights of Brazilian Snake Venom Metalloproteomics

Toxins, 2023
Snakebite envenoming is one of the most significantly neglected tropical diseases in the world. The lack of diagnosis/prognosis methods for snakebite is one of our motivations to develop innovative technological solutions for Brazilian health.
Bruna Cavecci-Mendonça, Karen Monique Luciano, Tauane Vaccas, Laudicéia Alves de Oliveira, Eloisa Fornaro Clemente, Bruno Cesar Rossini, José Cavalcante Souza Vieira, Luciana Curtolo de Barros, Ilka Biondi, Pedro de Magalhães Padilha, Lucilene Delazari dos Santos   +10 more
doaj   +1 more source

Autologous platelet‐rich plasma for healing chronic venous leg ulcers: Clinical efficacy and potential mechanisms

International Wound Journal, Volume 16, Issue 3, Page 788-792, June 2019., 2019
The overall quality of evidence of autologous platelet‐rich plasma (PRP) for treating chronic wounds remains low. While further well‐designed clinical studies are clearly required to convincingly demonstrate the efficacy of autologous PRP in improved healing of venous leg ulcers (VLUs) and other chronic wounds, there is also an increasing need to ...
Carolina D. Weller, Elizabeth E. Gardiner, Jane F. Arthur, Melissa Southey, Robert K. Andrews   +4 more
wiley   +1 more source