Results 61 to 70 of about 169,324 (244)

Aberrant GRP78 Phase Transition Sustains Endothelial IRE1α Signaling and Drives Blood–Brain Barrier Failure in Cerebral Amyloid Angiopathy

Advanced Science, EarlyView.
Vascular Aβ40 corrupts GRP78 phase behavior in brain endothelial cells, sustaining IRE1α–TRAF2–JNK signaling and driving apoptosis, tight junction loss, and blood–brain barrier failure in cerebral amyloid angiopathy. Pharmacological IRE1α inhibition restores vascular integrity, reduces leakage, and improves functional outcomes, revealing a targetable ...
Honglin Zheng, Qiang Li, Haiyang Luo, Yapei Yuan, Na Zhang, Yongting Lu, Suying Duan, Jieshi Zhong, Hang Zhang, Chenyang Liu, Yaochong Zhang, Wenzhuo Zhao, Yaxuan Song, Tuo Wang, Si Yan, Yapeng Li, Han Liu, Yuan Gao, Zongping Xia, Yuming Xu   +19 more
wiley   +1 more source

Covalently Integrated Selenoviologen–N‐Heterocyclic Carbene–Pt Nanoparticles for Visible‐Light‐Driven Hydrogen Evolution

Advanced Science, EarlyView.
A covalently integrated single‐component photocatalyst is constructed by anchoring selenoviologen to platinum nanoparticles via robust N‐heterocyclic carbene ligands. The resulting Pt─C covalent bonds function dually as protective structural scaffolds and direct channels for ultrafast intramolecular electron transfer This precise interfacial ...
Wenxi He, Guoping Li, Chenjing Liu, Yu Liu, Yawen Li, Wenxin Wei, Hairui Lei, Ni Yan, Gang He   +8 more
wiley   +1 more source

A Multi-Species Artificial Bee Colony Algorithm and Its Application for Crowd Simulation

IEEE Access, 2019
The artificial bee colony (ABC) algorithm has the problem of slow convergence and may be trapped into local optimum. In this paper, a multi-species ABC (MABC) algorithm is proposed based on the multi-swarm model.
Shouna Wang, Hong Liu, Kaizhou Gao, Jianxin Zhang   +3 more
doaj   +1 more source

Partial Phase‐Separation in the Initial Growth Stage of Exsolution‐Active SrTi0.95‐xNi0.05NbxO3‐δ Thin Films

Advanced Science, EarlyView.
Phase separation emerges during the initial growth of heavily Ni‐ and Ni,Nb‐co‐doped STO thin films, leading to preferential accumulation of Ni and embedded NiOx nanoinclusions in thicker films. Nb co‐doping partially suppresses the ordering of these embedded structures, comprising about 20% of all Ni ions.
Yen‐Po Liu, Moritz L. Weber, Dylan Jennings, Leonid L. Rusevich, Eugene Kotomin, Rainer Timm, Felix Gunkel, Regina Dittmann   +7 more
wiley   +1 more source

Crowd Evacuation Behaviour Modeling and Simulation in 3D Platform [PDF]

, 2020
Crowd simulation is an active research domain and is crucial for simulating crowd behaviour in certain condition such as normal or panic situation. The simulation is to show the interaction between the individual in a crowd.
Azlina, Binti Ahmadi Julaihi, Chiu, Po Chan, Hamizan, Binti Sharbini, Tan, Ping Ping   +3 more
core   +1 more source

Innovative Test Strip‐Based Colorimetric Sensors Integrated With Affinity Chromatography: Acetylcholinesterase Inhibitor Screening Breakthrough in Lycium Barbarum Leaves

Advanced Science, EarlyView.
Schematic diagrams illustrating the breakthrough in the screening of AChE inhibitors from LBL, and the research process of the pharmacodynamics of the NCP are presented. ABSTRACT Current Alzheimer's drugs exhibit limited effectiveness, highlighting the necessity for multi‐target treatments.
Yuping Sa, Hui Yuan, Jingui Ma, Zhigang Yang, Mei Wang, Weibiao Wang, Lingling Yang, Fen Ma, Weiman Zhang, Gidion Wilson Mening'oo, Guoning Chen, Xueqin Ma   +11 more
wiley   +1 more source

Study of Split-Flow Wall Located at Exit

Advances in Civil Engineering, 2017
Congestion is the major cause of crowd stampede-trampling and crushing incidents. To alleviate the phenomenon of congestion in the process of evacuation, theory of split-flow wall is put forward to optimize the evacuation and the principle of it is ...
Guomin Zhao, Min Li, Yunfeng Zhao, Qingsong Zhng, Zhongxian Liu   +4 more
doaj   +1 more source

An Overview of Crowd Evacuation Simulation [PDF]

, 2017
Emergency scenario is an unforeseen situation that threated human life. Emergency action plans comprising crowd evacuation is essential to prevent the occurrence of human injury and death.
Mazlina, Abdul Majid, Noor Akma, Abu Bakar, Khalid, Adam   +2 more
core   +1 more source

Stacking Pressure‐Driven Interfacial Dynamics in Anode‐Free Solid‐State Lithium Batteries

Advanced Science, EarlyView.
Using a three‐electrode setup, it is found that stacking pressure improves both anode and cathode interfaces but more effectively stabilizes the anode. Under low pressure, a sudden anode resistance rise indicates contact loss. Higher pressure delays this via Li creep and plastic deformation, maintaining interfacial contact.
Jianneng Liang, Matthias Bohnen, Ralf Müller, Robert Leiter, Simon Fleischmann, Shuya Gong, Mervyn Rohit Soans, Stefano Passerini, Alberto Varzi   +8 more
wiley   +1 more source

Cellular automaton model of crowd evacuation inspired by slime mould

, 2015
© 2015 Taylor & Francis. In all the living organisms, the self-preservation behaviour is almost universal. Even the most simple of living organisms, like slime mould, is typically under intense selective pressure to evolve a response to ensure their ...
Georgilas, Ioannis, Papadopoulos, D. P., Sirakoulis, G. Ch, Kalogeiton, Vicky, Sirakoulis, Georgios, Adamatzky, Andrew, Kalogeiton, V. S., Papadopoulos, Dim, Georgilas, I. P., Adamatzky, A. I.   +9 more
core   +1 more source