Results 61 to 70 of about 631,469 (197)

ApoE plasma levels and risk of cardiovascular mortality in old age.

PLoS Medicine, 2006
BackgroundThe epsilon2, epsilon3, and epsilon4 alleles of the apolipoprotein E gene (APOE) encode three isoforms, apoE2, E3, and E4, respectively. The apoE isoforms circulate in different plasma concentrations, but plasma concentrations of the same ...
Simon P Mooijaart, Jimmy F P Berbée, Diana van Heemst, Louis M Havekes, Anton J M de Craen, P Eline Slagboom, Patrick C N Rensen, Rudi G J Westendorp   +7 more
doaj   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Serum Total SOD Activity and SOD1/2 Concentrations in Predicting All-Cause Mortality in Lung Cancer Patients

Pharmaceuticals, 2021
Redox status disturbances are known during carcinogenesis and may have influence on patients’ survival. However, the prediction of mortality in lung cancer patients based on serum total SOD activity, and concentrations of its isoforms, has not been ...
Katarzyna Beata Skórska, Sylwia Płaczkowska, Anna Prescha, Irena Porębska, Monika Kosacka, Konrad Pawełczyk, Katarzyna Zabłocka-Słowińska   +6 more
doaj   +1 more source

Bisphenol A and Its Analogs: Toxicity Analysis in Mouse and Rat Liver—A Review

Journal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA) and its analogs are widely recognized for their use in industry and plastic manufacturing. Consequently, humans and animals are continually exposed to various substances in their daily lives. This review evaluates the hepatic toxicity of BPA and its analogs in mice and rats, with particular emphasis on molecular mechanisms ...
Sevda Bagdatli, Muhammed Canik, Gizem Gencay, Nurbanu Zengin, Tarık Dinc, Nazan Deniz Yön   +5 more
wiley   +1 more source

The effects of c-reactive protein (CRP) isoforms on inflammation and wound healing processes [PDF]

, 2017
C-reactive protein (CRP) is a homopentameric acute-phase inflammatory protein that exhibits elevated expression during inflammation. CRP can be found in its pentameric form (nCRP) or monomeric form (mCRP).
Hall, Nicola, Rachel
core  

Mean textural characters, size and ground attribution of volcanic clasts in sediment core CRP-3 (Table 4.2)

, 2006
Mean textural characters, size and ground attribution of volcanic clasts in sediment core CRP-3 (Table 4 ...
CRP Science Team (6968168), CRP Science Team   +1 more
core   +1 more source

The effect of immunomodulatory drugs on aortic stenosis: a Mendelian randomisation analysis

Scientific Reports, 2023
There are currently no approved pharmacological treatment options for aortic stenosis (AS), and there are limited identified drug targets for this chronic condition.
Jonathan L. Ciofani, Daniel Han, Milad Nazarzadeh, Usaid K. Allahwala, Giovanni Luigi De Maria, Adrian P. Banning, Ravinay Bhindi, Kazem Rahimi   +7 more
doaj   +1 more source

Small apolipoprotein(a) isoforms may predict primary patency following peripheral arterial revascularization

JVS: Vascular Science
Background High lipoprotein (a) [Lp(a)] is associated with adverse limb events in patients undergoing lower extremity revascularization. Lp(a) levels are genetically pre-determined, with LPA gene encoding for two apolipoprotein (a) [apo(a)] isoforms ...
Marianna Pavlyha, M. Hunter, Roman Nowygrod, Virenda I. Patel, Nicholas J. Morrissey, D. Bajakian, Yi-Hao Li, Gissette Reyes-Soffer   +7 more
semanticscholar   +1 more source

Natural Products Exhibit Therapeutic Potential in Treating Rheumatoid Arthritis by Targeting the PI3K/Akt Signaling Pathway

Phytotherapy Research, EarlyView.
This review summarizes how natural products, mainly including flavonoids, terpenoids, alkaloids, and polyphenols alleviate RA via PI3K/Akt pathway, regulating inflammation, proliferation, apoptosis, angiogenesis, and osteoclast differentiation. The figure was created by Figdraw (https://www.figdraw.com/#/).
Haishuo Ren, Yige Wang, Wenjing Ma, Omachi Daniel Ogaji, Shujing Chen, Kunze Du, Xuemi Zhang, Bo Xu, Shanxing Zhai, Shiming Fang, Yanxu Chang   +10 more
wiley   +1 more source

C-reactive protein haplotypes and dispositional optimism in obese and nonobese elderly subjects [PDF]

, 2011
Background Chronic low-grade inflammation, characterized by elevated plasma levels of C-reactive protein (CRP), has been inversely associated with dispositional optimism.
Craen, A.J.M., Westendorp, R.G., P. Eline Slagboom, Anton J. M. de Craen, Kromhout, D., Johanna M. Geleijnse, Craen, A.J.M. de, Erik J. Giltay, Rius-Ottenheim, N., Rudi G. Westendorp, Geleijnse, J.M., Giltay, E.J., Slagboom, P.E., Mast, R.C. van der, Nathaly Rius-Ottenheim, Daan Kromhout, Frans G. Zitman, Roos C. van der Mast, Zitman, F.G., Rius Ottenheim, N.   +19 more
core   +1 more source