Results 61 to 70 of about 10,390 (133)

Plasmatic Profiling of Individuals With Combinations of Type 2 Diabetes Mellitus, Dyslipidemia and Periodontitis: A Cross‐Sectional Study

Oral Diseases, EarlyView.
ABSTRACT Aim The objective of this study was to investigate the global profile of plasmatic proteins of individuals affected simultaneously or not by type 2 diabetes mellitus (T2DM, well/poorly‐controlled), Dyslipidemia (DL), and Periodontitis (P). Methods Besides periodontal examination, plasma was collected for glycemic, and lipid analyses from 150 ...
François Isnaldo Dias Caldeira, Sâmia Cruz Tfaile Corbi, Alliny de Souza Bastos, Silvana Regina Perez Orrico, Cristiane Ribeiro Salmon, Yizhi Xiao, Walter Luiz Siqueira, Raquel Mantuaneli Scarel‐Caminaga   +7 more
wiley   +1 more source

Heat thermotherapy to improve cardiovascular function and cardiometabolic health: A systematic review and meta‐analysis

Experimental Physiology, EarlyView.
Abstract Heat thermotherapy (HT) is reported to promote cardiovascular (CV) and cardiometabolic health benefits. This systematic review and meta‐analysis (CRD42020193669) empirically investigated the efficacy of HT in improving CV and cardiometabolic parameters by assessing responses to single versus multiple HT bouts.
Ben S. Price, Samuel J. E. Lucas, Ashley P. Akerman, Rachel E. Gilworth, Rebekah A. I. Lucas   +4 more
wiley   +1 more source

Early identification of vascular cognitive impairment from a multimodal perspective: a combined diagnosis from targeted cognitive assessments, imaging biomarkers, and molecular fluid biomarkers to ecological behavioral characteristics

Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract Vascular cognitive impairment (VCI), the second leading cause of dementia, is characterized by heterogeneous pathophysiology and a potentially reversible early phase, underscoring the need for timely identification. This review synthesizes advances across four complementary domains – targeted cognitive assessments, imaging biomarkers ...
Wenqi Song, Xiaoqun Liu, Tianrui Yu, Yuanyuan Xiang, Peijie Fu, Moxin Wu, Xiaoping Yin, Xiaorong Zhang, Zhiying Chen   +8 more
wiley   +1 more source

Vitamin E‐Related Molecular Signatures in Adolescent Idiopathic Scoliosis: A Hypothesis‐Generating Multi‐Omics Analysis

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Integrative analysis of plasma miRNA data (GSE235203) and BM‐MSC transcriptomic data (GSE110359), combined with database‐derived VE/tocopherol target mapping, prioritized SOD1, GCLC, PTGS1, PTGS2, and KDR. Single‐cell localization, CellChat analysis, structural simulation, NHANES contextualization, and GSE286204 supported hypothesis‐generating links to
Ying Ma, Yuankun Han, Zhizhong Geng, Sitong Fang, Jun Ren, Shoujian Wang, Tianxiang He, Lingjun Kong, Min Fang   +8 more
wiley   +1 more source

Obstructive Sleep Apnea: Epidemiology, Pathophysiology, Complications, Diagnosis, Management, and Emerging Fibrosis‐Linked Remodeling

MedComm, Volume 7, Issue 8, August 2026.
Obstructive sleep apnea (OSA) is characterized by recurrent upper‐airway collapse, which generates key nocturnal stressors including intermittent hypoxia, sleep fragmentation, intrathoracic pressure stress, and sympathetic activation. These physiological disturbances converge on shared biological mechanisms, including oxidative stress, inflammation ...
Nhi Ho Thi Thuy, Thị Hằng Giang Phan, Ali Hussein Eid, Paola Maccioccu, Stefania Camboni, Gavino Casu, Anna Maria Posadino, Roberta Giordo, Gianfranco Pintus   +8 more
wiley   +1 more source

Haemostatic changes and bleeding with anti‐IL‐6 directed therapy in autoimmune diseases

British Journal of Pharmacology, Volume 183, Issue 15, Page 4111-4125, August 2026.
Abstract Anti‐IL‐6 directed therapy, especially tocilizumab (TCZ), is widely used for the treatment of autoimmune diseases such as rheumatoid arthritis, giant cell arteritis and systemic juvenile idiopathic arthritis. Next to being a master regulator of inflammation, IL‐6 also is an important regulator of haemostasis. Although generally well tolerated,
Charlotte D. C. C. van der Heijden, Loes C. Oskam, Lenny van Bon, Chantal P. Rovers   +3 more
wiley   +1 more source

Evaluate the Association Between IL-37 Isoform-C and D Gene Expression with the Severity and Activity of Rheumatoid Arthritis

مجلة الكوفة الطبية
Background: Rheumatoid arthritis (RA) is a systemic, chronic autoimmune condition characterized by joint inflammation and pain, leading to the degeneration of the joints and bones, which may develop into deformities.
Furqan Hasan Razzaq, Rana Fadhil Obaid
doaj   +1 more source

Positive correlation of airway resistance and serum asymmetric dimethylarginine (ADMA) in bronchial asthma patients lacking evidence for systemic inflammation

Allergy, Asthma & Clinical Immunology, 2018
Background Contribution of nitric-oxide (NO) pathway to the pathogenesis of bronchial asthma (asthma) is ambiguous as NO may confer both protective and detrimental effects depending on the NO synthase (NOS) isoforms, tissue compartments and underlying ...
Gabor Tajti, Csaba Papp, Laszlo Kardos, Sandor Keki, Krisztian Pak, Magdolna Emma Szilasi, Rudolf Gesztelyi, Angela Mikaczo, Andrea Fodor, Maria Szilasi, Judit Zsuga   +10 more
doaj   +1 more source

The effects of c-reactive protein (CRP) isoforms on inflammation and wound healing processes

C-reactive protein (CRP) is a homopentameric acute-phase inflammatory protein that exhibits elevated expression during inflammation. CRP can be found in its pentameric form (nCRP) or monomeric form (mCRP). To date there has been little research investigating the effects of these CRP isoforms in wound healing processes and age-related impaired healing ...
openaire   +2 more sources

An aptamer specifically targeting mCRP ameliorates experimental arthritis

Journal of Orthopaedic Translation
Background: Recent evidence highlights the important role of the liver–bone axis in the development of arthritis, particularly rheumatoid arthritis (RA) and osteoarthritis (OA). The liver secretes various factors that impact joint health, one of which is
Zhuqian Wang, Duoli Xie, Peixi Zhu, Jianmin Guo, Chunhao Cao, Yu Du, Aiping Lu, Chao Liang   +7 more
doaj   +1 more source