Results 41 to 50 of about 631,469 (197)

A Conformational Change in C-Reactive Protein Enhances Leukocyte Recruitment and Reactive Oxygen Species Generation in Ischemia/Reperfusion Injury

Frontiers in Immunology, 2018
IntroductionC-reactive protein circulates as a pentameric protein (pCRP). pCRP is a well-established diagnostic marker as plasma levels rise in response to tissue injury and inflammation.
Jan R. Thiele, Johannes Zeller, Jurij Kiefer, David Braig, Sheena Kreuzaler, Yvonne Lenz, Lawrence A. Potempa, Florian Grahammer, Florian Grahammer, Tobias B. Huber, Tobias B. Huber, Tobias B. Huber, M. Huber-Lang, Holger Bannasch, G. Björn Stark, Karlheinz Peter, Steffen U. Eisenhardt   +16 more
doaj   +1 more source

Modulation of the Tissue Expression Pattern of Zebrafish CRP-Like Molecules Suggests a Relevant Antiviral Role in Fish Skin

Biology, 2021
Recent studies suggest that short pentraxins in fish might serve as biomarkers for not only bacterial infections, as in higher vertebrates including humans, but also for viral ones.
Melissa Bello-Perez, Mikolaj Adamek, Julio Coll, Antonio Figueras, Beatriz Novoa, Alberto Falco   +5 more
doaj   +1 more source

Human Fcγ-receptors selectively respond to C-reactive protein (CRP) isoforms

bioRxiv
The pentameric C-reactive protein (pCRP), an acute-phase protein, binds to lysophosphatidylcholine (LPC) displayed on the surface of dying cells and microorganisms to activate the complement system and to opsonize immune cells via Fcγ-receptors (FcγRs ...
Anna Henning, Johanna Seer, J. Zeller, K. Peter, Julia Thomé, P. Kolb, S. U. Eisenhardt, Katja Hoffmann, Hartmut Hengel   +8 more
semanticscholar   +1 more source

Zebrafish C-reactive protein isoforms inhibit SVCV replication by blocking autophagy through interactions with cell membrane cholesterol

Scientific Reports, 2020
In the present work, the mechanisms involved in the recently reported antiviral activity of zebrafish C-reactive protein-like protein (CRP1-7) against the spring viraemia of carp rhabdovirus (SVCV) in fish are explored.
M. Bello-Pérez, P. Pereiro, J. Coll, B. Novoa, L. Perez, A. Falcó   +5 more
semanticscholar   +1 more source

Role of C-Reactive Protein at Sites of Inflammation and Infection

Frontiers in Immunology, 2018
C-reactive protein (CRP) is an acute inflammatory protein that increases up to 1,000-fold at sites of infection or inflammation. CRP is produced as a homopentameric protein, termed native CRP (nCRP), which can irreversibly dissociate at sites of ...
Nicola R. Sproston, Jason J. Ashworth
doaj   +1 more source

Minimal Collagen-Binding Epitope of Glycoprotein VI in Human and Mouse Platelets

Biomedicines, 2023
Glycoprotein VI (GPVI) is a platelet-specific receptor for collagen and fibrin, regulating important platelet functions such as platelet adhesion and thrombus growth. Although the blockade of GPVI function is widely recognized as a potent anti-thrombotic
Chao Han, Pengxuan Ren, Medina Mamtimin, Linus Kruk, Edita Sarukhanyan, Chenyu Li, Hans-Joachim Anders, Thomas Dandekar, Irena Krueger, Margitta Elvers, Silvia Goebel, Kristin Adler, Götz Münch, Thomas Gudermann, Attila Braun, Elmina Mammadova-Bach   +15 more
doaj   +1 more source

Description of sediment core CRP-1

, 1998
Description of sediment core CRP-
CRP Science Team (6968168), CRP Science Team   +1 more
core   +1 more source

From Homeostasis To Inflammation To Autoimmunity: The Potential Impact of CRP

Inflammation
C-reactive protein (CRP) is a highly conserved pentraxin, synthesized primarily in the liver, and is widely recognized as a highly sensitive biomarker for inflammation and tissue damage.
Mustafa Ahmed, Ping Yuan, Jia-Geng Lei, Zhao-Ming Tang, Ze-Rui Yang, L. Potempa, Hui-Ying Wang, Hai-Yun Li   +7 more
semanticscholar   +1 more source

14‐3‐3γ Protects Against Postoperative Cognitive Dysfunction by Regulating Tau Thr205 Phosphorylation and Synaptic Integrity

Advanced Science, EarlyView.
Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu, Xue Han, Heng Zhang, Chang Ye, Tianjiao Xia, Xiaoping Gu   +5 more
wiley   +1 more source

Biostratigraphical datum events in sediment core CRP-2/2A (Table 7.1)

, 2000
Biostratigraphical datum events in sediment core CRP-2/2A (Table 7 ...
CRP Science Team (6968168), CRP Science Team   +1 more
core   +1 more source