Results 111 to 120 of about 132,225 (219)

Evidence supporting a catalytic pentad mechanism for the proteasome and other N-terminal nucleophile enzymes

Nature Communications
Proteases are defined by their nucleophile but require additional residues to regulate their active sites, most often arranged as catalytic triads that control the generation and resolution of acyl-enzyme intermediates.
Darlene Fung, Aida Razi, Michael Pandos, Benjamin Velez, Erignacio Fermin Perez, Lea Adams, Shaun Rawson, Richard M. Walsh, John Hanna   +8 more
doaj   +1 more source

Stoichiometry‐Programmed MXenes via Precursor Engineering for High‐Performance EMI Shielding and Energy Storage

Advanced Materials, EarlyView.
Precursor carbon stoichiometry programs internal strain and oxygen substitution in Ti3AlCxO2‐x, deterministically switching Ti3CxO2‐xTz MXenes between highly aligned 2D nanosheets and spontaneous 1D nanoscrolls. This synthesis‐stage architecture control enables ultrathin X/W‐band EMI shielding with outstanding mass‐normalized performance and bending ...
Jaeeun Park, Ju‐Hyoung Han, Yujin Chae, Mincheal Kim, Juwon Han, Younggeun Jang, Young Ho Jin, Jaewon Wang, Shi‐Hyun Seok, Yeoseon Sim, Zonghoon Lee, EunMi Choi, Soon‐Yong Kwon   +12 more
wiley   +1 more source

Cryo-CLXEM introduces cryo-SXT to bridge the resolution gap in cryo-CLEM

Communications Biology
Cryo-imaging in cellular biology provides the means to visualize the cellular interior at close-to-native conditions. A cornerstone in the field has been cryo-correlative light and electron microscopy (cryo-CLEM), with cryo-visible light fluorescent ...
Johannes Groen, Anastasia Gazi, Sergey Kapishnikov, Anne Brelot, Matthijn Vos, Jost Enninga, Eva Pereiro, Anna Sartori-Rupp   +7 more
doaj   +1 more source

Field‐Effect Transistors from Artificial Charged Domain Walls in Stacked Van der Waals Ferroelectric α‐In2Se3

Advanced Materials, EarlyView.
This study utilizes the van der Waals stacking of ferroelectric α$\alpha$‐In2Se3 to fabricate in‐plane artificial charged domain walls. These charged domain walls are electrically accessible, gate‐tunable, and show 2–9 orders of magnitude higher conductance than charged domain walls from thin film ferroelectrics, allowing their integration in field ...
Shahriar Muhammad Nahid, Haiyue Dong, Gillian M. Nolan, SungWoo Nam, Nadya Mason, Pinshane Y. Huang, Arend M. van der Zande   +6 more
wiley   +1 more source

Three-dimensional interaction between Cinnamomum camphora and a sap-sucking psyllid insect (Trioza camphorae) revealed by nano-resolution volume electron microscopy

Communications Biology
Phloem-feeding insects present significant economic threats worldwide and remain challenging to understand due to their specialized feeding strategies. Significant advances in genetics, genomics, and biochemistry have greatly enriched our comprehension ...
Guan Wang, Jian-Sheng Guo, Hai-Jian Huang, Zeng-Rong Zhu, Chuan-Xi Zhang   +4 more
doaj   +1 more source

Dielectric and Gate Metal Engineering for Threshold Voltage Modulation in Enhancement Mode Monolayer MoS2 Field Effect Transistors

Advanced Materials, EarlyView.
Enhancement‐mode monolayer MoS2 FETs with low threshold voltage are essential for low‐power electronics. The threshold voltage can be tuned by the gate metal work function when the semiconductor/dielectric interface is clean. Interfaces between monolayer MoS2 and ZrO2 or hBN allow effective work‐function modulation of the threshold voltage, in contrast
Lixin Liu, Han Yan, Leyi Loh, Kamal Kumar Paul, Soumya Sarkar, Deepnarayan Biswas, Tien‐Lin Lee, Takashi Taniguchi, Kenji Watanabe, Manish Chhowalla, Yan Wang   +10 more
wiley   +1 more source

Structure and Antigenicity of Kaposi's Sarcoma‐Associated Herpesvirus Glycoprotein B

Advanced Science
Kaposi's sarcoma‐associated herpesvirus (KSHV), a member of the human γ‐herpesviruses family, exhibits extensive cellular tropism and is associated with Kaposi's sarcoma and various B‐cell malignancies.
Xin‐Yan Fang, Cong Sun, Chu Xie, Bing‐Zhen Cheng, Zheng‐Zhou Lu, Ge‐Xin Zhao, Sen‐Fang Sui, Mu‐Sheng Zeng, Zheng Liu   +8 more
doaj   +1 more source

Radiotherapy Enhancement by Gold Nanocluster‐functionalized Nanoliposomes Using Polychromatic Orthovoltage X‐ray Irradiation

Advanced Materials Interfaces, EarlyView.
Lipid drug carriers to which ultra‐small gold nanoparticles were added enabled more efficient radiotherapy of cultured pancreatic cancer tumors. These nanoparticles boosted radiation‐induced damage to tumors by generating more reactive molecules, though higher gold levels are needed for strong benefits.
Nazareth Milagros Carigga Gutierrez, Eaazhisai Kandiah, Sofia Leo, Erwan Dupont, Fabrizio Johnson‐Corrales, Marc‐André Hograindleur, Sarvenaz Keshmiri, Hélène Elleaume, Benoit Busser, Romain Haudecoeur, Véronique Jacob, Anthony Vella, Véronique Josserand, Maxime Henry, Jean‐Luc Coll, Amandine Hurbin, Xavier Le Guével, Mans Broekgaarden   +17 more
wiley   +1 more source

Hydrogel‐Based 3D‐Printable Stretchable Pressure Sensor

Advanced Materials Technologies, EarlyView.
We present a carbon‐black‐functionalized double‐network granular hydrogel (DNGH) pressure sensor capable of detecting pressures from 200 Pa, equivalent to a light finger touch, up to 500 kPa. The sensor exhibits signal drifts below 3.5% after 800 cycles and response times around 80 ms. Leveraging this broad sensing range, we 3D print this material into
Tianyu Yuan, Chenzhuo Li, Antonia Georgopoulou, John M. Kolinski, Esther Amstad   +4 more
wiley   +1 more source

Microfluidic Engineering of Chitosan‐Coated Nanoemulsions for Controlled Release and Stability in Space Pharmaceutics

Advanced Materials Technologies, EarlyView.
Microfluidic engineering enables the fabrication of chitosan‐coated, melatonin‐loaded nanoemulsions with controlled release and enhanced physicochemical stability for space pharmaceutics. Interfacial biopolymer coating modulates droplet behavior under accelerated thermal stress and simulated microgravity.
Modupe Adebowale, Nguyen Van Duc Long, Philip M Williams, Volker Hessel   +3 more
wiley   +1 more source