Results 11 to 20 of about 2,439,094 (286)
4D Cryo-Electron Microscopy of Proteins [PDF]
Journal of the American Chemical Society, 2013 Cryo-electron microscopy is a form of transmission electron microscopy that has been used to determine the 3D structure of biological specimens in the hydrated state and with high resolution. We report the development of 4D cryo-electron microscopy by integrating the fourth dimension, time, into this powerful technique.
Fitzpatrick, AWP +3 more
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Recent Advances in Cryo Electron Microscopy and Tomography [PDF]
Structural DynamicsIn the recent years, cryo-electron microscopy (cryo-EM) single-particle analysis (SPA) has greatly benefited from a multitude of technological advances cumulating in breaking the atomic-resolution barrier for biological macromolecules.
Eliza Nieweglowska +2 more
doaj +5 more sources
Cryo‐electron microscopy of cholinesterases, present and future [PDF]
Journal of Neurochemistry, 2020 AbstractAcetylcholinesterase (AChE) and butyrylcholinesterase (BChE) exist in a variety of oligomeric forms, each with defined cellular and subcellular distributions. Although crystal structures of AChE and BChE have been available for many years, structures of the physiologically relevant ChE tetramer were only recently solved by cryo‐electron ...
Miguel Ricardo Leung +1 more
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Artificial Intelligence in Cryo-Electron Microscopy
Life, 2022 Cryo-electron microscopy (cryo-EM) has become an unrivaled tool for determining the structure of macromolecular complexes. The biological function of macromolecular complexes is inextricably tied to the flexibility of these complexes.
Jeong Min Chung +2 more
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Cryo-electron Microscopy of Membrane Proteins [PDF]
, 2013 Electron crystallography is used to study membrane proteins in the form of planar, two-dimensional (2D) crystals, or other crystalline arrays such as tubular crystals. This method has been used to determine the atomic resolution structures of bacteriorhodopsin, tubulin, aquaporins, and several other membrane proteins.
Goldie, Kenneth N +5 more
openaire +6 more sources
Cryo-electron microscopy in color
Nature MethodsCryo-electron microscopy with energy resolution, using the EELS-STEM method, allows researchers to identify the approximate locations of certain heavier atoms within single frozen, hydrated protein particles.
Stahlberg, Henning, Stahlberg, H.
openaire +4 more sources
Transmission electron microscopy in cell biology: sample preparation techniques and image information [PDF]
, 2012 Podeu consultar el llibre complet a: http://hdl.handle.net/2445/32166Transmission electron microscopy is a proven technique in the field of cell biology and a very useful tool in biomedical research. Innovation and improvements in equipment together with
Cortadellas i Raméntol, Núria +2 more
core +7 more sources
3D solutions in transmission electron (Cryo) -microscopy in biology [PDF]
, 2012 Podeu consultar el llibre complet a: http://hdl.handle.net/2445/32166One of the main problems in transmission electron microscopy in the biological field is the tri-dimensionality.
Muela, Yolanda +4 more
core +6 more sources
Microsecond time-resolved cryo-electron microscopy [PDF]
Current Opinion in Structural BiologyMicrosecond time-resolved cryo-electron microscopy has emerged as a novel approach for directly observing proteins dynamics. By providing microsecond temporal and near-atomic spatial resolution, it has the potential to elucidate a wide range of dynamics that were previously inaccessible and therefore, to significantly advance our understanding of ...
Harder, Oliver Florian
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Recent advances in retroviruses via cryo-electron microscopy [PDF]
Retrovirology, 2018 Cryo-electron microscopy has undergone a revolution in recent years and it has contributed significantly to a number of different areas in biological research.
Johnson Mak, Alex de Marco
doaj +2 more sources