Constitutively active orphan G protein-coupled receptors through the lenses of cryo-electron microscopy. [PDF]
Argerich J +3 more
europepmc +1 more source
Organic solvent‐free lipid nanoparticles featuring PEtOx‐based stealth lipids enable efficient mRNA and CRISPR‐Cas9 delivery while exhibiting markedly improved biocompatibility compared with PEG‐based analogues. Their successful ex vivo and in vivo performance, combined with data‐driven formulation optimization, establishes a versatile platform that ...
Michael Streiber +21 more
wiley +1 more source
Purification of the Active-State G Protein-Coupled Receptor ADGRL4 for Cryo-Electron Microscopy Using a Modular Tag System and a Tethered mini-G<sub>q</sub>. [PDF]
Favara DM, Tate CG.
europepmc +1 more source
Native state structural and chemical characterisation of Pickering emulsions: A cryo-electron microscopy study. [PDF]
Fernandez Ainaga DL +7 more
europepmc +1 more source
Decoys Reveal Multiple Basins of Attraction for Cryo-Electron-Microscopy Flexible Fitting. [PDF]
Alshammari M, He J, Wriggers W.
europepmc +1 more source
Cryo‐FIB‐SEM is used to mill and image the interfaces of ice droplets frozen on PDMS coatings damaged by abrasion and cutting. Both high‐ and low‐real contact areas are revealed for the first time, with interpenetration dependent on the shape of asperities on the damaged surface.
Catherine M. Megregian +3 more
wiley +1 more source
“Dead Lithium” Formation and Mitigation Strategies in Anode‐Free Li‐Metal Batteries
Anode‐free lithium metal batteries, though promising due to their high energy density, face challenges from dead lithium formation. “Dead lithium”, disconnected from the anode, causes capacity loss, increased resistance, and safety risks. This review explores the origins of dead lithium, its impact on battery performance, and potential strategies for ...
Mozaffar Abdollahifar, Andrea Paolella
wiley +1 more source
Simultaneous polyclonal antibody sequencing and epitope mapping by cryo electron microscopy and mass spectrometry. [PDF]
Schulte D +3 more
europepmc +1 more source
ABSTRACT Single‐stranded DNA (ssDNA) solutions are promising innovations shaping the future of genetic research and medical therapies. In principle, biotechnological mass production of ssDNA can be achieved using Escherichia coli in a high‐cell density fed‐batch process by secreting phagemid particles derived from the filamentous M13 bacteriophages ...
Nathalie Hafner +4 more
wiley +1 more source
Cryo-Electron Microscopy Studies of Biomolecular Structure and Dynamics. [PDF]
Kulczyk AW.
europepmc +1 more source

