Results 221 to 230 of about 133,701 (285)

Covalent Network Formation Rate Controls Depletion‐Induced Supramolecular Assembly in Hybrid Double Network Hydrogels

Angewandte Chemie, EarlyView.
Tuning the rate of covalent network formation in hybrid double network hydrogels regulates whether supramolecular filaments retain their low‐nm structures or depletion‐induced supramolecular assembly takes place forming bundles. This kinetic handle programs the mesoscale architecture and toughness of the hydrogels, establishing a link between ...
Mertcan Özel, Sebastian Novosedlik, Tingxian Liu, Lucía López‐Gandul, Heleen Duijs, Hari Veera Prasad Thelu, Ciqing Tong, Roxanne E. Kieltyka   +7 more
wiley   +2 more sources

Correction of preferred orientation-induced distortion in cryo-electron microscopy maps. [PDF]

Sci Adv
Zhu D, Cao W, Li J, Wu C, Cao D, Zhang X.   +5 more
europepmc   +1 more source

Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis

Advanced NanoBiomed Research, EarlyView.
Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia, Akshay Pandey, Raffaele Spanò, Bianca Martins Estevão, Roberto Palomba, Greta Avancini, Tamaghna Gupta, Ana Maria Lopez Estevez, Stuart B. Goodman, Nidhi Bhutani, Paolo Decuzzi   +10 more
wiley   +1 more source

Production and cryo-electron microscopy structure of an internally tagged SARS-CoV-2 spike ecto-domain construct. [PDF]

J Struct Biol X
Singh S, Liu Y, Burke M, Rayaprolu V, Stein SE, Hasan SS.   +5 more
europepmc   +1 more source

Purification and Cryo-Electron Microscopy Analysis of Bacterial Appendages. [PDF]

Bio Protoc
Sanchez JC, Baumgardt JK, Wright ER.
europepmc   +1 more source

Structural insight into the DNMT1 reaction cycle by cryo-electron microscopy. [PDF]

PLoS One
De I, Weidenhausen J, Concha N, Müller CW.   +3 more
europepmc   +1 more source

Ribozymes for RNA‐Catalyzed RNA Methylation and Labeling

Angewandte Chemie International Edition, EarlyView.
Ribozymes are powerful tools for site‐specific RNA modification. Their activities range from installing tags and fluorophores to generating natural RNA methylations, making them valuable tools to uncover the many functions that RNA plays in nature.
Carolin P. M. Scheitl, Claudia Höbartner   +1 more
wiley   +1 more source

A cryo-electron microscopy structure of yeast Pex5 in complex with a cargo uncovers a novel binding interface.

J Cell Sci
Peer L, Dym O, Elad N, Tirosh A, Jacobovitch J, Sivan E, Angel M, Albeck S, Schuldiner M, Peleg Y, Zalckvar E.   +10 more
europepmc   +1 more source

Integrating Cryo-Electron Microscopy and Molecular Dynamics Simulations to Investigate Membrane Binding of Influenza Virus Fusion Peptides. [PDF]

J Am Chem Soc
Setny P, Borkowska P, Worch R.
europepmc   +1 more source