Results 51 to 60 of about 2,439,094 (286)
Study of protein structure by electron microscopy and single particle image processing [PDF]
, 2015 The molecular assemblies form an important role in the understanding the machinery of living cells. These assemblies with thickness less than 1000nm and exhibiting different shapes, size and biochemical states are studied using Transmission Electron ...
Dandey, Venkata Prasad
core +1 more source
Cryo-EM structural determination of PfFNT–MMV007839.
, 2021 (A) A representative cryo-EM micrograph of PfFNT- MMV007839. (B) A representative 2D classification average. (C) Flowchart for EM data processing of datasets. Details can be found in the Methods. cryo-EM, cryo-electron microscopy; EM, electron microscopy;
Yanxia Zhou (1447465) +17 more
core +1 more source
Cryo-electron microscopy of vitrified specimens [PDF]
Quarterly Reviews of Biophysics, 1988 Cryo-electron microscopy of vitrified specimens was just emerging as a practical method when Richard Henderson proposed that we should teach an EMBO course on the new technique. The request seemed to come too early because at that moment the method looked more like a laboratory game than a useful tool.
Dubochet, Jacques +6 more
openaire +3 more sources
Cryo-EM data collection and refinement statistics of PfFNT.
, 2021 cryo-EM, cryo-electron microscopy; PfFNT, P. falciparum formate–nitrite transporter. (DOCX)
Yanxia Zhou (1447465) +17 more
core +1 more source
A Frame-by-Frame Glance at Membrane Fusion Mechanisms: From Viral Infections to Fertilization
Biomolecules, 2023 Viral entry and fertilization are distinct biological processes that share a common mechanism: membrane fusion. In viral entry, enveloped viruses attach to the host cell membrane, triggering a series of conformational changes in the viral fusion proteins.
Farshad C. Azimi +5 more
doaj +1 more source
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Transfer of tilted sample information in transmission electron microscopy [PDF]
, 2010 When a transmission electron microscope is used in imaging mode, information carried by the sample function is transformed by the optics of the instrument during the imaging process.
Mariani, Valerio
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Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Structural Insights into Cell Wall-Related Vesicle Secretion with Different Mechanisms
PlantsExocytosis is a fundamental biological process in all eukaryotes involving the vesicular transport of cellular cargo to the plasma membrane or extracellular space.
Jiawen Yang +6 more
doaj +1 more source
eLife, 2023 Allosteric modulation of G protein-coupled receptors (GPCRs) is a major paradigm in drug discovery. Despite decades of research, a molecular-level understanding of the general principles that govern the myriad pharmacological effects exerted by GPCR ...
Ziva Vuckovic +23 more
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