Results 201 to 210 of about 2,441,948 (283)

From Unsupervised to Zero-Shot: 3D Domain Adaptation for Cryo-Electron Tomography Segmentation. [PDF]

Int J Comput Vis
Li H, Li X, Wang H, Shi J, Chen H, Du B, Barthelemy J, Kihara D, Shen J, Xu M.   +9 more
europepmc   +1 more source

Magnetic Resonance Reveals Radical Stability in Native Biofilms and Its Role in Bacterial Resistance

Angewandte Chemie, EarlyView.
The complex biofilm environment consists of planktonic bacterial cells and cells embedded in an extracellular matrix (ECM). Through an integrated magnetic resonance approach, we show that nitroxide radicals primarily interact with the polysaccharides and lipids in the ECM.
Alysia Mandato, Hannah Hunter, Sadhana Srinivasa, Chang‐Hyeock Byeon, Abdulkadir Tunc, Meghan K. Wells, Faith J. Scott, Frederic Mentink‐Vigier, Wook Kim, Sunil Saxena, Ümit Akbey   +10 more
wiley   +2 more sources

Preparation of Vitrified Mammalian Cells for In Situ Cryo-Electron Tomography. [PDF]

Curr Protoc
Martin-Solana E, Frendi S, Ning J, Banks-Tibbs T, Vockley J, Freyberg Z.   +5 more
europepmc   +1 more source

Direct Observation of Radical‐Mediated Oxide‐to‐Alloy Transformation in Solution Under Pulsed Laser Irradiation

Angewandte Chemie, EarlyView.
Time‐resolved in situ x‐ray absorption spectroscopy and DFTB‐based molecular dynamics simulations identify direct hydrogen atom transfer from ethanol to lattice oxygen as the elementary step of laser‐driven reduction in NiCo2O4. While this transfer is facile, the subsequent release of lattice oxygen is entropy‐driven and becomes accessible only at ...
Woo Hyeok Kim, Sieon Jung, Ahreum Min, Raja Arumugam Senthil, Juhyeon Park, Wonil Seo, Seung Yeon Choi, Junu Bae, Cheolhee Yang, In‐hui Hwang, Joonghan Kim, Tae Wu Kim, Myong Yong Choi   +12 more
wiley   +2 more sources

Cryo-electron tomography reveals coupled flavivirus replication, budding and maturation. [PDF]

Nat Commun
Dahmane S, Schexnaydre E, Zhang J, Singh BK, Rosendal E, Chotiwan N, Sharma KB, Nilsson E, Peters MBA, Yau WL, Rönfeldt S, Lundmark R, Barad BA, Grotjahn DA, Liese S, Carlson A, Överby AK, Carlson LA.   +17 more
europepmc   +1 more source

A DNA G‐Quadruplex‐Targeting Ligand Suppresses c‐MYC Expression: Implications for Gemcitabine‑Resistant Pancreatic Cancer

Angewandte Chemie, EarlyView.
PQB‐4, a fluorescent small‐molecule ligand that targets c‐MYC DNA G‐quadruplexes (G4s), showed marked synergy with gemcitabine in resistant PANC‐1 cells (CI = 0.027). In vivo, the ligand reduced tumor weight by 44% in a PANC‐1 xenograft model. These results highlight the therapeutic potential of c‐MYC DNA G4‐targeting ligands for treating gemcitabine ...
Bo‐Xin Zheng, Ya‐Kun Wang, Ze‐Xin Chen, Yi‐Wen Meng, Meng‐Ting She, Jia‐Peng Dong, Yingying Zheng, Yao‐Xun Zeng, Wen‐De Zheng, Wei Long, Wing‐Leung Wong   +10 more
wiley   +2 more sources

In-cell cryo-electron tomography reveals differential effects of type I and type II kinase inhibitors on LRRK2 filament formation and microtubule association. [PDF]

Elife
Basiashvili T, Hutchings J, Chen S, Karasmanis EP, Flaherty WA, Leschziner AE, Villa E.   +6 more
europepmc   +1 more source

Visualizing influenza A virus assembly by in situ cryo-electron tomography. [PDF]

Nat Commun
Wachsmuth-Melm M, Peterl S, O'Riain A, Makroczyová J, Fischer K, Krischuns T, Vale-Costa S, Amorim MJ, Chlanda P.   +8 more
europepmc   +1 more source

Strategies for studying discrete heterogeneity in situ using cryo-electron tomography. [PDF]

Curr Opin Struct Biol
Bartesaghi A.
europepmc   +1 more source

Cryo-electron tomography reveals the microtubule-bound form of inactive LRRK2. [PDF]

Elife
Chen S, Basiashvili T, Hutchings J, Sanz Murillo M, Villagran Suarez A, Xiong E, Alegrio Louro J, Leschziner AE, Villa E.   +8 more
europepmc   +1 more source