Results 71 to 80 of about 166,403 (367)

A Vascular Microphysiological Model of Lung Fibrosis Reveals That Myofibroblasts and IPF Patient‐Derived Fibroblasts Impair Angiogenesis and Vasculogenesis

open access: yesAdvanced Functional Materials, EarlyView.
A microphysiological lung fibrosis model recapitulates myofibroblast–vascular interactions. Induced myofibroblasts and patient‐derived IPF fibroblasts impair angiogenesis and increase vascular permeability via TGF‐β1–driven signaling. Pharmacological interventions with SB 431542 and VEGF supplementation restore vascular morphology and barrier function.
Elena Cambria   +7 more
wiley   +1 more source

A Bayesian Approach to Optimizing Stem Cell Cryopreservation protocols

open access: yes, 2014
Cryopreservation is beset with the challenge of protocol alignment across a wide range of cell types and process variables. By taking a cross-sectional assessment of previously published cryopreservation data (sample means and standard errors) as ...
Sambu, S
core   +1 more source

Coconut Cryopreservation: Present Status and Future Prospects

open access: yesCORD, 2017
Coconut is one of the most important small holder crops worldwide. Conservation of coconut as seeds or field gene banks is not effective due to a range of limitations.
Iroshini Welewanni, Dharshani Bandupriya
doaj   +1 more source

Oocyte Cryopreservation in Domestic Animals and Humans: Principles, Techniques and Updated Outcomes

open access: yesAnimals, 2021
Simple Summary Oocyte cryopreservation is the most powerful technique for preserving the genetic potential of individual females. However, the recent outcomes of this technology in terms of viability, fertilizing ability, embryo development and pregnancy
T. Tharasanit, P. Thuwanut
semanticscholar   +1 more source

Progressive Insights into 3D Bioprinting for Corneal Tissue Restoration

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores the potential of 3D bioprinting to replicate the complex structure and function of the human cornea. It highlights key advances in bioink development, printing modalities, and in vivo performance, while addressing current challenges and emerging strategies. The review emphasizes bioprinting's promise to overcome donor shortages and
Ilayda Namli   +6 more
wiley   +1 more source

Implications of storage and handling conditions on glass transition and potential devitrification of oocytes and embryos [PDF]

open access: yes, 2014
Devitrification, the process of crystallization of a formerly crystal-free, amorphous glass state, can lead to damage during the warming of cells.
Sansinena, Marina Julia   +3 more
core   +1 more source

Oocyte, embryo and blastocyst cryopreservation in ART: systematic review and meta-analysis comparing slow-freezing versus vitrification to produce evidence for the development of global guidance

open access: yesHuman Reproduction Update, 2016
BACKGROUND Successful cryopreservation of oocytes and embryos is essential not only to maximize the safety and efficacy of ovarian stimulation cycles in an IVF treatment, but also to enable fertility preservation.
L. Rienzi   +7 more
semanticscholar   +1 more source

The Future of Cryopreservation in Assisted Reproductive Technologies

open access: yesFrontiers in Endocrinology, 2020
Societal changes and the increasing desire and opportunity to preserve fertility have increased the demand for effective assisted reproductive technologies (ART) and have increased the range of scenarios in which ART is now used.
E. Bosch, M. De Vos, P. Humaidan
semanticscholar   +1 more source

Photosensitizing Lipid Nanoparticles for Ferroptosis‐Enhanced Photodynamic Cancer Therapy via GPX4 Silencing

open access: yesAdvanced Healthcare Materials, EarlyView.
Photosensitizing lipid nanoparticles (PLNPs) are engineered by incorporating cholesterol–PEG–pheophorbide a into MC3‐based LNPs and encapsulating GPX4‐targeting siRNA. Upon light activation, PLNPs generate reactive oxygen species (ROS) while silencing GPX4 to induce ferroptosis.
Ga‐Hyun Bae   +9 more
wiley   +1 more source

Single-wall carbon nanotubes improve cell survival rate and reduce oxidative injury in cryopreservation of Agapanthus praecox embryogenic callus

open access: yesPlant Methods, 2020
Background Cryopreservation is the best way for long-term in vitro preservation of plant germplasm resources. The preliminary studies found that reactive oxygen species (ROS) induced oxidative stress and ice-induced membrane damage are the fundamental ...
Li Ren   +6 more
doaj   +1 more source

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