Results 81 to 90 of about 98,488 (287)

A Mathematical Model for Determining Probabilistic Design Space in Mesenchymal Stem Cell Passage Culture

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT With their many therapeutic functions, mesenchymal stem cells (MSCs) are promising sources for regenerative medicine. However, in the manufacture of MSCs, without a method for exploring the effects of long‐term passage on cell proliferation potentials, the design of passage culture processes is challenging.
Keita Hirono   +4 more
wiley   +1 more source

A Bayesian Approach to Optimizing Stem Cell Cryopreservation protocols

open access: yes, 2014
Cryopreservation is beset with the challenge of protocol alignment across a wide range of cell types and process variables. By taking a cross-sectional assessment of previously published cryopreservation data (sample means and standard errors) as ...
Sambu, S
core   +1 more source

DNA fragmentation index (DFI) as a measure of sperm quality and fertility in mice. [PDF]

open access: yes, 2020
Although thousands of genetically modified mouse strains have been cryopreserved by sperm freezing, the likelihood of cryorecovery success cannot be accurately predicted using conventional sperm parameters.
Li, Ming-Wen, Lloyd, KC Kent
core   +1 more source

Fertility preservation in ovarian tumours [PDF]

open access: yes, 2018
A considerable number of patients with a cancer diagnosis are of childbearing age and have not satisfied their desire for a family. Despite ovarian cancer (OC) usually occurring in older patients, 3%–14% are diagnosed at a fertile age with the overall 5 ...
Bardhi, E.   +8 more
core   +1 more source

Optimizing biophysical properties of cellular niches to enhance stem cell‐derived extracellular vesicle function in musculoskeletal regeneration

open access: yesBMEMat, EarlyView.
Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu   +9 more
wiley   +1 more source

Endogenous luteinizing hormone concentration and IVF outcome during ovarian stimulation in fixed versus flexible GnRH antagonist protocols: An RCT

open access: yesInternational Journal of Reproductive BioMedicine, 2018
Background: Luteinizing hormone (LH) is essential for normal follicular development and oocyte maturation. In particular, fluctuations of LH during the follicular phase have a significant impact on morphological and functional changes of the oocyte and ...
Raffaella Depalo   +5 more
doaj  

Cryopreservation practices in clinical and preclinical iPSC‐based cell therapies: Current challenges and future directions

open access: yesBiotechnology Progress, EarlyView.
Abstract Induced pluripotent stem cells (iPSCs) offer significant therapeutic potential, but cryopreservation challenges, particularly the reliance on cytotoxic Dimethyl Sulfoxide (Me2SO), hinder their clinical application. This review examines current cryopreservation practices in clinical and preclinical iPSC‐based therapies, highlighting the ...
Michael Dobruskin   +2 more
wiley   +1 more source

Ice Inhibition for Cryopreservation: Materials, Strategies, and Challenges

open access: yesAdvanced Science, 2021
Cryopreservation technology has developed into a fundamental and important supporting method for biomedical applications such as cell‐based therapeutics, tissue engineering, assisted reproduction, and vaccine storage.
Tie Chang, Gang Zhao
doaj   +1 more source

Oocyte cryopreservation as an adjunct to the assisted reproductive technologies [PDF]

open access: yes, 2007
The document attached has been archived with permission from the editor of the Medical Journal of Australia. An external link to the publisher’s copy is included.
Esler, J.   +6 more
core   +2 more sources

MODELING OF THE KINETICS OF CRYOGENIC FREEZING OF LIMA BEAN SEEDS AS A FUNCTION OF INITIAL WATER CONTENT [PDF]

open access: yesEngenharia Agrícola
Cryopreservation is a technique used to preserve genetic material at ultra-low temperatures in cryogenic germplasm banks. In order to enable the cryopreservation of a seed, it is necessary to study its appropriate freezing temperature and its water ...
Karina M da F. Luciano   +3 more
doaj   +2 more sources

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