Results 71 to 80 of about 10,077,982 (396)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Comparison of silver and molybdenum microfocus X-ray sources for single-crystal structure determination

Journal of Applied Crystallography, 2015
A detailed comparison of single-crystal diffraction data collected with Ag Kα and Mo Kα microsources (IµS) indicates that the Ag Kα data are better when absorption is significant. Empirical corrections intended to correct for absorption also correct well
L. Krause, R. Herbst‐Irmer, G. Sheldrick, D. Stalke   +3 more
semanticscholar   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Branch-Chain-Rich Diisopropyl Ether with Steric Hindrance Facilitates Stable Cycling of Lithium Batteries at − 20 °C

Nano-Micro Letters
Highlights Branch chain-rich diisopropyl ether (DIPE) was selected as co-solvent of low-temperature electrolyte for lithium metal battery. The introduction of DIPE improved the disorder of electrolyte and the branch chains from DIPE exclude other ...
Houzhen Li, Yongchao Kang, Wangran Wei, Chuncheng Yan, Xinrui Ma, Hao Chen, Yuanhua Sang, Hong Liu, Shuhua Wang   +8 more
doaj   +1 more source

1D versus 2D cocrystals growth via microspacing in-air sublimation

Nature Communications, 2019
Organic cocrystals have interesting properties owing to synergistic effects of the individual components but development of effective growth methods for molecular cocrystals is still in its primary stage. Here the authors demonstrate a sublimation method
Xin Ye, Yang Liu, Qing Guo, Quanxiang Han, Chao Ge, Shuangyue Cui, Leilei Zhang, Xutang Tao   +7 more
doaj   +1 more source

Ribbon Crystals

PLoS ONE, 2013
A repetitive crystal-like pattern is spontaneously formed upon the twisting of straight ribbons. The pattern is akin to a tessellation with isosceles triangles, and it can easily be demonstrated with ribbons cut from an overhead transparency. We give a general description of developable ribbons using a ruled procedure where ribbons are uniquely ...
Bohr, Jakob, Markvorsen, Steen
openaire   +5 more sources

Optimization of crystal extraction experiment [PDF]

, 1996
Using a computer model for the crystal extraction, we investigate the bent-crystal parameters optimal for the extraction experiment. The optimal crystal curvature is found to be near 1 GeV/cm (for pv/R), i.e.
Akbari, Akbari, Altuna, Asseev, Asseev, Biryukov, Biryukov, Biryukov, Biryukov, Biryukov, Biryukov, Biryukov, Biryukov, Carrigan, Chesnokov, Ferroni, Murphy, Shih, Taratin, Taratin, Tsyganov, Valery Biryukov   +21 more
core   +3 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Soliton walls paired by polar surface interactions in a ferroelectric nematic liquid crystal

Nature Communications, 2022
Surface interactions are usually polar along the normal to the interface and apolar within the interface. Here, the authors find that polar in-plane surface interactions produce domain structures in the bulk of a ferroelectric nematic liquid crystal.
Bijaya Basnet, Mojtaba Rajabi, Hao Wang, Priyanka Kumari, Kamal Thapa, Sanjoy Paul, Maxim O. Lavrentovich, Oleg D. Lavrentovich   +7 more
doaj   +1 more source

Once Upon a Time...When a Revolution Evolved to a Civil War in Syria [PDF]

, 2019
This paper gives an overview of how the conflict in Syria has evolved from a revolution into a sectarian civil war. Power is maintained by the ruling Assad family through promotion of the Alawite minority within the government and military.
Myers, Crystal M
core   +1 more source