Results 91 to 100 of about 15,579 (272)

Exploring the Universe within the Human Lens Through Raman Spectroscopy

Delhi Journal of Ophthalmology, 2017
Ever since the emergence of refined modalities of cataract surgery, the looming question has been the same - How to improve the technique, to minimize manipulation of biological components and optimize the end result? The most recent development has been,
Praveen K Malik, Taru Dewan, Ayasha Nishad, Pulkit Gupta   +3 more
doaj   +1 more source

Identification of hydrophobic sites on UV irradiated beta crystallins from bovine lenses [abstract] [PDF]

, 2004
only availableFaculty Mentor: Dr. Krishna Sharma, OphthalmologyThe lens of the eye is an avascular tissue of a complex network of proteins surrounded by a capsule.
Rednam, Rukmini
core  

Development of cataract caused by diabetes mellitus: Raman study [PDF]

, 2004
Diabetes mellitus succeeded by diabetic cataract was induced to experimental animals (Wistar rats) by applying an Alloxan injection. Eye properties deterioration were monitored from clinical standpoint and using Raman and infrared spectroscopies.
Furić, Krešimir, Hadžija, Mirko, Mohaček Grošev, Vlasta   +2 more
core   +1 more source

Winter Temperature Affects Fatty Acid Composition and Gene Expression, but Not Fat Content and Survival in a Northern Population of a Range‐Expanding Spider

Ecology and Evolution, Volume 15, Issue 12, December 2025.
This study provides insight into the performance of a range‐expanding species and the physiological and molecular mechanisms underlying thermal tolerance at its expanding edge. ABSTRACT Species expand their geographic distribution when environmental conditions are favorable or when mutations arise that allow them to live in previously unfavorable ...
Carolina Ortiz‐Movliav, Marina Wolz, Michael Klockmann, Andreas Walter Kuss, Lars Riff Jensen, Corinna Jensen, Alexander Wacker, Gabriele B. Uhl   +7 more
wiley   +1 more source

Association of High Myopia with Crystallin Beta A4 (CRYBA4) Gene Polymorphisms in the Linkage-Identified MYP6 Locus [PDF]

, 2012
Background: Myopia is the most common ocular disorder worldwide and imposes tremendous burden on the society. It is a complex disease. The MYP6 locus at 22 q12 is of particular interest because many studies have detected linkage signals at this interval.
Fung, WY, Ho, DWH, Ng, PW, Yap, MKH, Yip, SP   +4 more
core   +1 more source

Effects of geranylgeranylacetone on diastolic and microvascular function in patients with heart failure with a preserved ejection fraction: A phase 2, randomized, placebo‐controlled, crossover trial

European Journal of Heart Failure, Volume 27, Issue 12, Page 3304-3311, December 2025.
Abstract Aims Heart failure with preserved ejection fraction (HFpEF) is a major healthcare burden with limited treatment options. Geranylgeranylacetone (GGA) has been shown to improve myocardial compliance and endothelial function in preclinical models.
Soufiane Nassiri, Geert H.D. Voordes, Loek van Heerebeek, Daniël H. van Raalte, Marianne C. Verhaar, Daan J. Touw, Merle M. Krebber, Dirk J. Duncker, Etto C. Eringa, M. Louis Handoko, Adriaan A. Voors, on behalf of the RECONNEXT Consortium   +11 more
wiley   +1 more source

Unraveling the Role of Ensheathing Cells and Perineural Fibroblasts in Olfactory Neurogenesis

Glia, Volume 73, Issue 12, Page 2407-2426, December 2025.
Main Points DEOs are similar to satellite glial cells. DECs react to neuronal injury by promoting lipid metabolism, but do not proliferate. ECs reduce gap junctions upon neuronal injury. Perineural fibroblasts also contribute to the injury response. ABSTRACT During development and following injury‐induced neurogenesis, olfactory ensheathing cells (OECs)
Katja Senf, Sandor Nietzsche, Martin Westermann, Eva M. Neuhaus   +3 more
wiley   +1 more source

R405W Desmin Knock‐In Mice Highlight Alterations of Mitochondria, Protein Quality Control and Myofibrils in Myofibrillar Myopathy

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 6, December 2025.
ABSTRACT Background Mutations in the desmin gene cause skeletal myopathies and cardiomyopathies. The objective of this study was to elucidate the molecular pathology induced by the expression of R405W mutant desmin in murine skeletal muscle. Methods A comprehensive characterization of the skeletal muscle pathology in hetero‐ and homozygous R405W desmin
Sabrina Batonnet‐Pichon, Florence Delort, Alain Lilienbaum, Carolin Berwanger, Dorothea Schultheis, Ursula Schlötzer‐Schrehardt, Andreas Schmidt, Steffen Uebe, Yosra Baiche, Tom J. Eisenack, Débora Broch Trentini, Markus Mallek, Leonid Mill, Ana Ferreiro, Bettina Eberhard, Thomas Lücke, Markus Krüger, Christian Thiel, Rolf Schröder, Christoph S. Clemen   +19 more
wiley   +1 more source

Differentiation state-specific mitochondrial dynamic regulatory networks are revealed by global transcriptional analysis of the developing chicken lens. [PDF]

, 2014
The mature eye lens contains a surface layer of epithelial cells called the lens epithelium that requires a functional mitochondrial population to maintain the homeostasis and transparency of the entire lens.
Anastas, Sara, Basu, Subhasree, Brennan, Lisa A., Chauss, Daniel, Gau, Victoria, Hejtmancik, J. Fielding, Kantorow, Marc, Ma, Zhiwei, Menko, A. Sue, Rajakaruna, Suren   +9 more
core   +3 more sources

Small‐Molecule Targeting MuRF1 Protects Against Denervation‐Induced Diaphragmatic Dysfunction: Underlying Molecular Mechanisms

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 6, December 2025.
ABSTRACT Background Mechanical inactivity rapidly induces diaphragm muscle fibres' contractile dysfunction and atrophy. Diaphragm weakness can impair respiratory function, quality of life and increase risks of morbidity and mortality. Muscle RING‐finger protein‐1 (MuRF1) expression is upregulated during denervation and muscle inactivity and is known to
Fernando Ribeiro, Paulo R. Jannig, Siegfried Labeit, Anselmo S. Moriscot   +3 more
wiley   +1 more source