Results 101 to 110 of about 8,769 (230)

Post-translationally modified human lens crystallin fragments show aggregation in vitro

open access: yesBiochemistry and Biophysics Reports, 2017
Background: Crystallin fragments are known to aggregate and cross-link that lead to cataract development. This study has been focused on determination of post-translational modifications (PTMs) of human lens crystallin fragments, and their aggregation ...
O.P. Srivastava   +3 more
doaj   +1 more source

Engineered Elastin‐Like Polypeptides: Intelligent Self‐Assembling Platforms for Biomedical Application

open access: yesSmall Structures, Volume 7, Issue 3, March 2026.
Armed with unique structural and functional properties, elastin‐like polypeptides attract their attentions as programmable materials in biomedical applications, including fusion tags for protein and nucleic acid purification; nanocarriers for protein, chemotherapeutics, and imaging agent delivery; hydrogels for tissue regeneration, 3D model ...
Yang Yuan   +9 more
wiley   +1 more source

Introns as Protective Buffers Against Transposable Elements Invasion During Genome Gigantism in a Newt

open access: yesGenes to Cells, Volume 31, Issue 2, March 2026.
In the giant Pleurodeles waltl genome, introns serve as “structural buffers,” absorbing transposable elements (TEs) to protect coding exons. While this enables “gene body inflation,” persistent TE accumulation eventually leads to transcriptional silencing and functional collapse, or “burst,” of the gene architecture.
Kazuto Bou, Kiyokazu Agata
wiley   +1 more source

Genotype‐Dependent Transcriptome Divergence Associated With Variation at vgll3 in Juvenile Gilthead Seabream (Sparus aurata)

open access: yesMolecular Ecology, Volume 35, Issue 6, March 2026.
ABSTRACT Early developmental processes significantly influence growth and maturation patterns, aquaculture traits that are critical for physiological adaptation and productivity. The vestigial‐like family member 3 gene (vgll3) plays a key role in growth and maturation across diverse taxa, including mammals and teleost fishes.
Aristotelis Moulistanos   +6 more
wiley   +1 more source

Protein refractive index increment is determined by conformation as well as composition. [PDF]

open access: yes, 2018
The refractive index gradient of the eye lens is controlled by the concentration and distribution of its component crystallin proteins, which are highly enriched in polarizable amino acids.
Bierma, Jan C   +4 more
core  

Sugarcane Small Heat Shock Proteins Facilitate Sugarcane Mosaic Virus Replication via Interaction With the Movement Protein P3N‐PIPO

open access: yesMolecular Plant Pathology, Volume 27, Issue 3, March 2026.
SCMV targets small heat shock proteins (ScHSP17.5 and ScHSP17.9A) via P3N‐PIPO to evade sugarcane immunity and enhance replication, revealing key host–virus interactions for breeding strategies. ABSTRACT Sugarcane mosaic virus (SCMV) causes substantial yield losses worldwide, yet the molecular basis underlying resistance and susceptibility in sugarcane
Yuan Yuan   +5 more
wiley   +1 more source

Elucidating the mechanism of anti-apoptotic activity of α-crystallin and its therapeutic potential [PDF]

open access: yesJournal of Stress Physiology & Biochemistry
α- Crystallins are the structural proteins of the eye lens which possess anti-apoptotic activity. Both αA- and αB- crystallins are distinct antiapoptotic regulators which can interact with Bax and Bcl-XS, proapoptotic members of the Bcl-2 family in order
Aparajita Chakraborty   +2 more
doaj  

Influence of Thermal Perturbation of the Oligomeric Size of -Crystallin on its Chaperone Function – A Biophysical Study [PDF]

open access: yes, 2010
-Crystallin is the major protein component of the vertebrate eye lens and is composed of two subunits A- and B-, 20 kDa each having 57% sequence homology between them. Both subunits associate to form large oligomer of 800 kDa average molecular weight. It
Laha, B
core  

An Exploration of Human D-Crystallin Affinity for Potential Aggregation Inhibitors: A Molecular Docking Investigation

open access: yesStudia Universitatis Babes-Bolyai Chemia
Cataract, the leading cause of blindness worldwide, is characterized by the presence of a cloudy area in the eye lens resulting in a loss of transparency.
Călin G. FLOARE   +3 more
doaj   +1 more source

Phase Behavior of Short Range Square Well Model

open access: yes, 2004
Various Monte Carlo techniques are used to determine the complete phase diagrams of the square well model for the attractive ranges $\lambda = 1.15$ and $\lambda = 1.25$.
Allen M. P.   +3 more
core   +1 more source

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