Results 101 to 110 of about 8,769 (230)
Post-translationally modified human lens crystallin fragments show aggregation in vitro
Background: Crystallin fragments are known to aggregate and cross-link that lead to cataract development. This study has been focused on determination of post-translational modifications (PTMs) of human lens crystallin fragments, and their aggregation ...
O.P. Srivastava +3 more
doaj +1 more source
Armed with unique structural and functional properties, elastin‐like polypeptides attract their attentions as programmable materials in biomedical applications, including fusion tags for protein and nucleic acid purification; nanocarriers for protein, chemotherapeutics, and imaging agent delivery; hydrogels for tissue regeneration, 3D model ...
Yang Yuan +9 more
wiley +1 more source
In the giant Pleurodeles waltl genome, introns serve as “structural buffers,” absorbing transposable elements (TEs) to protect coding exons. While this enables “gene body inflation,” persistent TE accumulation eventually leads to transcriptional silencing and functional collapse, or “burst,” of the gene architecture.
Kazuto Bou, Kiyokazu Agata
wiley +1 more source
ABSTRACT Early developmental processes significantly influence growth and maturation patterns, aquaculture traits that are critical for physiological adaptation and productivity. The vestigial‐like family member 3 gene (vgll3) plays a key role in growth and maturation across diverse taxa, including mammals and teleost fishes.
Aristotelis Moulistanos +6 more
wiley +1 more source
Protein refractive index increment is determined by conformation as well as composition. [PDF]
The refractive index gradient of the eye lens is controlled by the concentration and distribution of its component crystallin proteins, which are highly enriched in polarizable amino acids.
Bierma, Jan C +4 more
core
SCMV targets small heat shock proteins (ScHSP17.5 and ScHSP17.9A) via P3N‐PIPO to evade sugarcane immunity and enhance replication, revealing key host–virus interactions for breeding strategies. ABSTRACT Sugarcane mosaic virus (SCMV) causes substantial yield losses worldwide, yet the molecular basis underlying resistance and susceptibility in sugarcane
Yuan Yuan +5 more
wiley +1 more source
Elucidating the mechanism of anti-apoptotic activity of α-crystallin and its therapeutic potential [PDF]
α- Crystallins are the structural proteins of the eye lens which possess anti-apoptotic activity. Both αA- and αB- crystallins are distinct antiapoptotic regulators which can interact with Bax and Bcl-XS, proapoptotic members of the Bcl-2 family in order
Aparajita Chakraborty +2 more
doaj
Influence of Thermal Perturbation of the Oligomeric Size of -Crystallin on its Chaperone Function – A Biophysical Study [PDF]
-Crystallin is the major protein component of the vertebrate eye lens and is composed of two subunits A- and B-, 20 kDa each having 57% sequence homology between them. Both subunits associate to form large oligomer of 800 kDa average molecular weight. It
Laha, B
core
Cataract, the leading cause of blindness worldwide, is characterized by the presence of a cloudy area in the eye lens resulting in a loss of transparency.
Călin G. FLOARE +3 more
doaj +1 more source
Phase Behavior of Short Range Square Well Model
Various Monte Carlo techniques are used to determine the complete phase diagrams of the square well model for the attractive ranges $\lambda = 1.15$ and $\lambda = 1.25$.
Allen M. P. +3 more
core +1 more source

